Literature DB >> 31123767

Plea for a standardized imaging approach to disorders of sex development in neonates: consensus proposal from European Society of Paediatric Radiology task force.

Fred E Avni1, Heloise Lerisson2, Maria-Luisa Lobo3, Maryse Cartigny4, Marcello Napolitano5, Hans-J Mentzel6, Michael Riccabona7, Magdalena Wozniak8, Damjana Kljucevsek9, Thomas A Augdal10, Bruno Constanza11, Donald Ibe12, Kassa Darge13, Samuel Stafrace14, Philippe Petit15, Lil-Sofie Ording Muller16.   

Abstract

This consensus article elaborated by the European Society for Paediatric Radiology task force on gastrointestinal and genitourinary imaging is intended to standardize the imaging approach in newborns with disorders of sex development. These newborns represent a difficult and stressful situation necessitating a multidisciplinary team approach. Imaging plays an important role in the work-up but needs to be optimized and customized to the patient. Ultrasound plays the central role in assessing the genital anatomy. The examination must be conducted in a detailed and systematic way. It must include transabdominal and transperineal approaches with adapted high-resolution transducers. The pelvic cavity, the genital folds, the inguinal areas and the adrenals must be evaluated as well as the rest of the abdominal cavity. A reporting template is proposed. The indications of magnetic resonance imaging and cysto- and genitography are discussed as well as they may provide additional information. Imaging findings must be reported cautiously using neutral wording as much as possible.

Entities:  

Keywords:  Adrenals; Congenital anomalies; Disorders of sex development; Genital tract; Magnetic resonance imaging; Neonates; Sexual differentiation; Ultrasound

Mesh:

Year:  2019        PMID: 31123767     DOI: 10.1007/s00247-019-04414-4

Source DB:  PubMed          Journal:  Pediatr Radiol        ISSN: 0301-0449


  24 in total

1.  Prenatal measurement of testicular diameter by ultrasonography: development of fetal male gender and evaluation of testicular descent.

Authors:  M Rotondi; F Valenzano; E Bilancioni; G Spanò; M Rotondi; C Giorlandino
Journal:  Prenat Diagn       Date:  2001-02       Impact factor: 3.050

Review 2.  Sonographic fetal sex determination.

Authors:  Marwan Odeh; Vatali Granin; Mohamed Kais; Ella Ophir; Jacob Bornstein
Journal:  Obstet Gynecol Surv       Date:  2009-01       Impact factor: 2.347

3.  Transperineal ultrasonography.

Authors:  Jennifer K Son; George A Taylor
Journal:  Pediatr Radiol       Date:  2013-11-08

Review 4.  Ovary and testicle and everything in between: lesions and imaging in the newborn.

Authors:  Hansel J Otero; Eva Rubio; Anna Blask
Journal:  Semin Ultrasound CT MR       Date:  2015-02-03       Impact factor: 1.875

Review 5.  Prenatal management of disorders of sex development.

Authors:  Lyn S Chitty; Pierre Chatelain; Katja P Wolffenbuttel; Yves Aigrain
Journal:  J Pediatr Urol       Date:  2012-11-04       Impact factor: 1.830

Review 6.  Management of disorders of sex development.

Authors:  Olaf Hiort; Wiebke Birnbaum; Louise Marshall; Lutz Wünsch; Ralf Werner; Tatjana Schröder; Ulla Döhnert; Paul-Martin Holterhus
Journal:  Nat Rev Endocrinol       Date:  2014-07-15       Impact factor: 43.330

7.  Fetal sex determination using NIPT and ultrasound as a method for diagnosing important fetal sex abnormalities.

Authors:  Tara A Lynch; Kathleen Ruzzo; Virginia Sack; Asha Rijhsinghani
Journal:  Prenat Diagn       Date:  2016-07-26       Impact factor: 3.050

8.  Size of testes, ovaries, uterus and breast buds by ultrasound in healthy full-term neonates ages 0-3 days.

Authors:  Summer L Kaplan; J Christopher Edgar; Eileen G Ford; Margaret A Adgent; Joan I Schall; Andrea Kelly; David M Umbach; Walter J Rogan; Virginia A Stallings; Kassa Darge
Journal:  Pediatr Radiol       Date:  2016-08-31

Review 9.  Imaging Techniques in the Diagnostic Journey of Disorders of Sex Development.

Authors:  Gil Guerra-Junior; Kleber C Andrade; Irene H K Barcelos; Andréa T Maciel-Guerra
Journal:  Sex Dev       Date:  2017-08-22       Impact factor: 1.824

Review 10.  Caring for individuals with a difference of sex development (DSD): a Consensus Statement.

Authors:  Martine Cools; Anna Nordenström; Ralitsa Robeva; Joanne Hall; Puck Westerveld; Christa Flück; Birgit Köhler; Marta Berra; Alexander Springer; Katinka Schweizer; Vickie Pasterski
Journal:  Nat Rev Endocrinol       Date:  2018-07       Impact factor: 43.330

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  3 in total

Review 1.  Intracavitary contrast-enhanced ultrasonography in children: review with procedural recommendations and clinical applications from the European Society of Paediatric Radiology abdominal imaging task force.

Authors:  Damjana Ključevšek; Michael Riccabona; Lil-Sofie Ording Müller; Magdalena Maria Woźniak; Stéphanie Franchi-Abella; Kassa Darge; Hans-Joachim Mentzel; Aikaterini Ntoulia; Fred Efraim Avni; Marcello Napolitano; Luisa Lobo; Annemieke Simone Littooij; Thomas Angell Augdal; Costanza Bruno; Beatrice Maria Damasio; Donald Ibe; Samuel Stafrace; Philippe Petit
Journal:  Pediatr Radiol       Date:  2020-02-13

Review 2.  Clinical spectrum of female genital malformations in prenatal diagnosis.

Authors:  Michael R Mallmann; Ulrich Gembruch
Journal:  Arch Gynecol Obstet       Date:  2022-02-27       Impact factor: 2.344

3.  Diagnosis of DSD in Children-Development of New Tools for a Structured Diagnostic and Information Management Program within the Empower-DSD Study.

Authors:  Katja Wechsung; Louise Marshall; Martina Jürgensen; Uta Neumann
Journal:  J Clin Med       Date:  2022-07-03       Impact factor: 4.964

  3 in total

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