Literature DB >> 31120515

Health Utility Values as an Outcome Measure in Patients Undergoing Functional Septorhinoplasty.

Shekhar K Gadkaree1, Jennifer C Fuller2, Natalie S Justicz1, Rachel E Weitzman1, Adeeb Derakhshan1, Suresh Mohan1, Robin W Lindsay1.   

Abstract

IMPORTANCE: By measuring health utility values (HUVs) for patients with nasal obstruction after septorhinoplasty, the association of nasal congestion with overall health can be measured and the functional outcomes of septorhinoplasty can be determined.
OBJECTIVE: To use the EuroQol 5-Dimension (EQ-5D) questionnaire to evaluate nasal obstruction outcomes after septorhinoplasty and to determine HUVs. DESIGN, SETTING, AND PARTICIPANTS: This prospective cohort study included patients who underwent septorhinoplasty for nasal obstruction at a single institution by a single surgeon from January 1, 2013, through December 31, 2017. Participants completed the EQ-5D questionnaire immediately before surgery and postoperatively at 2, 4, 6, and 12 months. The EQ-5D scores were converted to HUVs using population-based data for individuals with chronic diseases. Data were analyzed from May 1 through December 31, 2018. EXPOSURE: Functional septorhinoplasty. MAIN OUTCOMES AND MEASURES: Preoperative and postoperative EQ-5D scores were compared to evaluate improvement in overall health after septorhinoplasty.
RESULTS: A total of 463 patients (53.8% women; mean [SD] age, 36.8 [15.7] years) who underwent septorhinoplasty and completed EQ-5D surveys at baseline and postoperatively were included in the study population. Overall mean (SD) preoperative HUV was 0.872 (0.01), compared with 1.00 for those with a perfect state of health. On univariate analysis, female sex (mean [SD] HUV, 0.853 [0.01]; P = .004), previous nasal surgery (mean [SD] HUV, 0.85 [0.16]; P = .02), previous septoplasty (mean [SD] HUV, 0.88 [0.15]; P = .02), and previous sinus surgery (mean [SD] HUV, 0.79 [0.20]; P = .009) were associated with significantly lower baseline HUVs. On multivariate regression including these variables, only previous septoplasty was significantly associated with a positive change in mean (SD) HUV (0.88 [0.15] vs 0.85 [0.16]; P = .02). Mean (SD) HUV was significantly improved at 2 months postoperatively to 0.91 (0.14; P = .001) and remained significantly improved from baseline at 12 months, at 0.93 (0.13; P < .001). CONCLUSIONS AND RELEVANCE: Nasal obstruction is associated with significant detriment to overall health, in line with other chronic conditions affecting the US population. Functional septorhinoplasty appears to substantially improve overall health, as measured by HUV, in an immediate and sustained fashion. LEVEL OF EVIDENCE: 3.

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Year:  2019        PMID: 31120515      PMCID: PMC6547223          DOI: 10.1001/jamafacial.2019.0234

Source DB:  PubMed          Journal:  JAMA Facial Plast Surg        ISSN: 2168-6076            Impact factor:   4.611


  17 in total

Review 1.  Health outcomes in economic evaluation: the QALY and utilities.

Authors:  Sarah J Whitehead; Shehzad Ali
Journal:  Br Med Bull       Date:  2010-10-29       Impact factor: 4.291

Review 2.  Measurement of health state utilities for economic appraisal.

Authors:  G W Torrance
Journal:  J Health Econ       Date:  1986-03       Impact factor: 3.883

3.  US valuation of the EQ-5D health states: development and testing of the D1 valuation model.

Authors:  James W Shaw; Jeffrey A Johnson; Stephen Joel Coons
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4.  Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies.

Authors:  Erik von Elm; Douglas G Altman; Matthias Egger; Stuart J Pocock; Peter C Gøtzsche; Jan P Vandenbroucke
Journal:  BMJ       Date:  2007-10-20

5.  Generalizability of valuations on health states collected with the EuroQolc-questionnaire.

Authors:  M L Essink-Bot; M E Stouthard; G J Bonsel
Journal:  Health Econ       Date:  1993-10       Impact factor: 3.046

6.  US norms for six generic health-related quality-of-life indexes from the National Health Measurement study.

Authors:  Dennis G Fryback; Nancy Cross Dunham; Mari Palta; Janel Hanmer; Jennifer Buechner; Dasha Cherepanov; Shani A Herrington; Ron D Hays; Robert M Kaplan; Theodore G Ganiats; David Feeny; Paul Kind
Journal:  Med Care       Date:  2007-12       Impact factor: 2.983

7.  Assessment of the EuroQol 5-Dimension Questionnaire for Detection of Clinically Significant Global Health-Related Quality-of-Life Improvement Following Functional Septorhinoplasty.

Authors:  Jennifer C Fuller; Patricia A Levesque; Robin W Lindsay
Journal:  JAMA Facial Plast Surg       Date:  2017-03-01       Impact factor: 4.611

8.  Development and preliminary testing of the new five-level version of EQ-5D (EQ-5D-5L).

Authors:  M Herdman; C Gudex; A Lloyd; Mf Janssen; P Kind; D Parkin; G Bonsel; X Badia
Journal:  Qual Life Res       Date:  2011-04-09       Impact factor: 4.147

9.  The health impact of chronic sinusitis in patients seeking otolaryngologic care.

Authors:  R E Gliklich; R Metson
Journal:  Otolaryngol Head Neck Surg       Date:  1995-07       Impact factor: 5.591

10.  What is the proper way to apply the multiple comparison test?

Authors:  Sangseok Lee; Dong Kyu Lee
Journal:  Korean J Anesthesiol       Date:  2018-08-28
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  1 in total

1.  A Systematic Review of Health State Utility Values in the Plastic Surgery Literature.

Authors:  Adrienne N Christopher; Martin P Morris; Viren Patel; Kevin Klifto; John P Fischer
Journal:  Plast Reconstr Surg Glob Open       Date:  2021-11-29
  1 in total

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