Literature DB >> 31097980

A Medicinal Chemist's Perspective on Transitioning from Industry to Academic Drug Discovery.

James C Barrow1,2.   

Abstract

Medicinal chemists have increasing opportunities to transition from the pharmaceutical industry to academic medical centers interested in translational research. This Viewpoint highlights some of the differences between these two cultures and strategies to succeed in academic drug discovery.

Year:  2019        PMID： 31097980      PMCID： PMC6511952          DOI： 10.1021/acsmedchemlett.9b00107

Source DB:  PubMed          Journal:  ACS Med Chem Lett        ISSN： 1948-5875            Impact factor:   4.345


  6 in total

Review 1.  Diagnosing the decline in pharmaceutical R&D efficiency.

Authors:  Jack W Scannell; Alex Blanckley; Helen Boldon; Brian Warrington
Journal:  Nat Rev Drug Discov       Date:  2012-03-01       Impact factor: 84.694

Review 2.  Academic drug discovery: current status and prospects.

Authors:  Jeremy R Everett
Journal:  Expert Opin Drug Discov       Date:  2015-06-19       Impact factor: 6.098

3.  Drug discovery in an academic setting: playing to the strengths.

Authors:  Donna M Huryn
Journal:  ACS Med Chem Lett       Date:  2013-01-17       Impact factor: 4.345

Review 4.  Mitigating risk in academic preclinical drug discovery.

Authors:  Jayme L Dahlin; James Inglese; Michael A Walters
Journal:  Nat Rev Drug Discov       Date:  2015-04       Impact factor: 84.694

Review 5.  Contributions of academic laboratories to the discovery and development of chemical biology tools.

Authors:  Donna M Huryn; Lynn O Resnick; Peter Wipf
Journal:  J Med Chem       Date:  2013-05-31       Impact factor: 7.446

6.  The promise and peril of chemical probes.

Authors:  Cheryl H Arrowsmith; James E Audia; Christopher Austin; Jonathan Baell; Jonathan Bennett; Julian Blagg; Chas Bountra; Paul E Brennan; Peter J Brown; Mark E Bunnage; Carolyn Buser-Doepner; Robert M Campbell; Adrian J Carter; Philip Cohen; Robert A Copeland; Ben Cravatt; Jayme L Dahlin; Dashyant Dhanak; Aled M Edwards; Mathias Frederiksen; Stephen V Frye; Nathanael Gray; Charles E Grimshaw; David Hepworth; Trevor Howe; Kilian V M Huber; Jian Jin; Stefan Knapp; Joanne D Kotz; Ryan G Kruger; Derek Lowe; Mary M Mader; Brian Marsden; Anke Mueller-Fahrnow; Susanne Müller; Ronan C O'Hagan; John P Overington; Dafydd R Owen; Saul H Rosenberg; Bryan Roth; Brian Roth; Ruth Ross; Matthieu Schapira; Stuart L Schreiber; Brian Shoichet; Michael Sundström; Giulio Superti-Furga; Jack Taunton; Leticia Toledo-Sherman; Chris Walpole; Michael A Walters; Timothy M Willson; Paul Workman; Robert N Young; William J Zuercher
Journal:  Nat Chem Biol       Date:  2015-08       Impact factor: 15.040
  6 in total
  1 in total

1.  The Resurrection of Phenotypic Drug Discovery.

Authors:  Wayne E Childers; Khaled M Elokely; Magid Abou-Gharbia
Journal:  ACS Med Chem Lett       Date:  2020-03-06       Impact factor: 4.345
  1 in total

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