Claudio Vergari1, Laurent Gajny2, Isabelle Courtois3, Eric Ebermeyer3, Kariman Abelin-Genevois4, Youngwoo Kim2, Tristan Langlais5, Raphael Vialle5, Ayman Assi6, Ismat Ghanem6, Jean Dubousset2, Wafa Skalli2. 1. LBM/Institut de Biomécanique Humaine Georges Charpak, Arts et Métiers ParisTech, 151 bd de l'Hôpital, 75013, Paris, France. c.vergari@gmail.com. 2. LBM/Institut de Biomécanique Humaine Georges Charpak, Arts et Métiers ParisTech, 151 bd de l'Hôpital, 75013, Paris, France. 3. Unite Rachis, CHU - Hospital Bellevue, Saint-Étienne, France. 4. Department of Orthopaedic Surgery, Centre médico-chirurgical et de réadaptation des Massues, Lyon, France. 5. Department of Paediatric Orthopaedics, Armand Trousseau Hospital, APHP, Sorbonne University, 26, avenue du Docteur Arnold-Netter, 75012, Paris, France. 6. Laboratory of Biomechanics and Medical Imaging, Faculty of Medicine, University of Saint-Joseph, Beirut, Lebanon.
Abstract
PURPOSE: To validate the predictive power and reliability of a novel quasi-automatic method to calculate the severity index of adolescent idiopathic scoliosis (AIS). METHODS: Fifty-five AIS patients were prospectively included (age 10-15, Cobb 16° ± 4°). Patients underwent low-dose biplanar X-rays, and a novel fast method for 3D reconstruction of the spine was performed. They were followed until skeletal maturity (stable patients) or brace prescription (progressive patients). The severity index was calculated at the first examination, based on 3D parameters of the scoliotic curve, and it was compared with the patient's final outcome (progressive or stable). Three operators have repeated the 3D reconstruction twice for a subset of 30 patients to assess reproducibility (through Cohen's kappa and intra-class correlation coefficient). RESULTS: Eighty-five percentage of the patients were correctly classified as stable or progressive by the severity index, with a sensitivity of 92% and specificity of 74%. Substantial intra-operator agreement and good inter-operator agreement were observed, with 80% of the progressive patients correctly detected at the first examination. The novel severity index assessment took less than 4 min of operator time. CONCLUSIONS: The fast and semiautomatic method for 3D reconstruction developed in this work allowed for a fast and reliable calculation of the severity index. The method is fast and user friendly. Once extensively validated, this severity index could allow very early initiation of conservative treatment for progressive patients, thus increasing treatment efficacy and therefore reducing the need for corrective surgery. These slides can be retrieved under Electronic Supplementary Material.
PURPOSE: To validate the predictive power and reliability of a novel quasi-automatic method to calculate the severity index of adolescent idiopathic scoliosis (AIS). METHODS: Fifty-five AISpatients were prospectively included (age 10-15, Cobb 16° ± 4°). Patients underwent low-dose biplanar X-rays, and a novel fast method for 3D reconstruction of the spine was performed. They were followed until skeletal maturity (stable patients) or brace prescription (progressive patients). The severity index was calculated at the first examination, based on 3D parameters of the scoliotic curve, and it was compared with the patient's final outcome (progressive or stable). Three operators have repeated the 3D reconstruction twice for a subset of 30 patients to assess reproducibility (through Cohen's kappa and intra-class correlation coefficient). RESULTS: Eighty-five percentage of the patients were correctly classified as stable or progressive by the severity index, with a sensitivity of 92% and specificity of 74%. Substantial intra-operator agreement and good inter-operator agreement were observed, with 80% of the progressive patients correctly detected at the first examination. The novel severity index assessment took less than 4 min of operator time. CONCLUSIONS: The fast and semiautomatic method for 3D reconstruction developed in this work allowed for a fast and reliable calculation of the severity index. The method is fast and user friendly. Once extensively validated, this severity index could allow very early initiation of conservative treatment for progressive patients, thus increasing treatment efficacy and therefore reducing the need for corrective surgery. These slides can be retrieved under Electronic Supplementary Material.
Entities:
Keywords:
3D reconstruction; Adolescent idiopathic scoliosis; Feature extraction; Reliability; Severity index
Authors: Vincent Pomero; David Mitton; Sébastien Laporte; Jacques A de Guise; Wafa Skalli Journal: Clin Biomech (Bristol, Avon) Date: 2004-03 Impact factor: 2.063
Authors: Zongshan Hu; Claudio Vergari; Laurent Gajny; Zhen Liu; Tsz-Ping Lam; Zezhang Zhu; Yong Qiu; Gene C W Man; Kwong-Hang Yeung; Winnie C W Chu; Jack C Y Cheng; Wafa Skalli Journal: Quant Imaging Med Surg Date: 2021-07