Literature DB >> 3106983

Nonrandom allele associations between unlinked protein loci: are the polymorphisms of the immunoglobulin constant regions adaptive?

W van der Loo, C P Arthur, B J Richardson, M Wallage-Drees, R Hamers.   

Abstract

Consistent linkage disequilibrium was observed between independently segregating protein loci. In natural populations of the European rabbit Oryctolagus cuniculus, highly significant, nonrandom associations between alleles of the constant regions of the immunoglobulin light and heavy chains were found, both within localities and between localities. We suggest that the population genetic data presented here are relevant to the adaptive significance of the genetic polymorphisms of the antibody constant regions.

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Year:  1987        PMID： 3106983      PMCID： PMC304806          DOI： 10.1073/pnas.84.9.3075

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  22 in total

1.  Ig gamma restriction fragment length polymorphisms indicate an ancient separation of Caucasian haplotypes.

Authors:  M J Johnson; G de Lange; L L Cavalli-Sforza
Journal:  Am J Hum Genet       Date:  1986-05       Impact factor: 11.025

2.  Linkage disequilibrium in subdivided populations.

Authors:  M Nei; W H Li
Journal:  Genetics       Date:  1973-09       Impact factor: 4.562

Review 3.  The organization, expression, and evolution of antibody genes and other multigene families.

Authors:  L Hood; J H Campbell; S C Elgin
Journal:  Annu Rev Genet       Date:  1975       Impact factor: 16.830

4.  Proceedings: Phylogeny of the rabbit immunoglobulin light-chain markers: Distribution of determinants associated with rabbit b-locus in different lagomorph families.

Authors:  W van der Loo; C Hamers-Casterman; R Hamers
Journal:  Arch Int Physiol Biochim       Date:  1976-02

5.  Allelic and nonallelic homology of a supergene family.

Authors:  T Ohta
Journal:  Proc Natl Acad Sci U S A       Date:  1982-05       Impact factor: 11.205

6.  Disequilibrium, selection, and recombination: limits in two-locus, two-allele models.

Authors:  A Hastings
Journal:  Genetics       Date:  1981-07       Impact factor: 4.562

7.  Allelic exclusion and control of endogenous immunoglobulin gene rearrangement in kappa transgenic mice.

Authors:  K A Ritchie; R L Brinster; U Storb
Journal:  Nature       Date:  1984 Dec 6-12       Impact factor: 49.962

8.  Double line phenotypes in rabbit IgG allotypes and their relation to the cis/trans configuration of the IgG markers.

Authors:  C Hamers-Casterman; E Wittouck; G Florent; W Van der Loo; P De Baetselier; R Hamers
Journal:  J Immunogenet       Date:  1977-10

9.  Structural basis of the A14 and A15 allotypic specificities in rabbit immunoglobulin G.

Authors:  E Appella; A Chersi; R G Mage; S Dubiski
Journal:  Proc Natl Acad Sci U S A       Date:  1971-06       Impact factor: 11.205

10.  Allotypy of rabbit serum proteins. I. Immuno-chemical analysis leading to the individualization of seven main allotypes.

Authors:  J OUDIN
Journal:  J Exp Med       Date:  1960-07-01       Impact factor: 14.307
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  8 in total

1.  Symbiont survival and host-symbiont disequilibria under differential vertical transmission.

Authors:  M S Sánchez; J Arnold; M A Asmussen
Journal:  Genetics       Date:  2000-03       Impact factor: 4.562

2.  Linkage disequilibrium in natural and experimental populations of Drosophila melanogaster.

Authors:  Z Smit-McBride; A Moya; F J Ayala
Journal:  Genetics       Date:  1988-12       Impact factor: 4.562

Review 3.  An overview of the lagomorph immune system and its genetic diversity.

Authors:  Ana Pinheiro; Fabiana Neves; Ana Lemos de Matos; Joana Abrantes; Wessel van der Loo; Rose Mage; Pedro José Esteves
Journal:  Immunogenetics       Date:  2015-09-23       Impact factor: 2.846

Review 4.  Molecular bases of genetic diversity and evolution of the immunoglobulin heavy chain variable region (IGHV) gene locus in leporids.

Authors:  Ana Pinheiro; Dennis Lanning; Paulo C Alves; Rose G Mage; Katherine L Knight; Wessel van der Loo; Pedro J Esteves
Journal:  Immunogenetics       Date:  2011-05-20       Impact factor: 2.846

5.  Compensatory aspects of allele diversity at immunoglobulin loci: gene correlations in rabbit populations devoid of light chain diversity (Oryctolagus cuniculus L.; Kerguelen Islands).

Authors:  W Van der Loo; P Boussès; C P Arthur; J L Chapuis
Journal:  Genetics       Date:  1996-11       Impact factor: 4.562

6.  Estimation of gene diversity at the b locus of the constant region of the immunoglobulin light chain in natural populations of European rabbit (Oryctolagus cuniculus) in Portugal, Andalusia and on the Azorean Islands.

Authors:  W van der Loo; N Ferrand; R C Soriguer
Journal:  Genetics       Date:  1991-04       Impact factor: 4.562

7.  Variance analysis of immunoglobulin alleles in natural populations of rabbit (Oryctolagus cuniculus): the extensive interallelic divergence at the b locus could be the outcome of overdominance-type selection.

Authors:  W van der Loo
Journal:  Genetics       Date:  1993-09       Impact factor: 4.562

8.  Evidence for contrasting modes of selection at interacting globin genes in the European rabbit (Oryctolagus cuniculus).

Authors:  R Campos; J F Storz; N Ferrand
Journal:  Heredity (Edinb)       Date:  2008-04-30       Impact factor: 3.821
  8 in total

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