Literature DB >> 31057680

Current Status and Growth of Nuclear Theranostics in Singapore.

Hian Liang Huang1,2, Aaron Kian Ti Tong1,2, Sue Ping Thang1,2, Sean Xuexian Yan1,2, Winnie Wing Chuen Lam1,2, Kelvin Siu Hoong Loke1,2, Charlene Yu Lin Tang1, Lenith Tai Jit Cheng1, Gideon Su Kai Ooi1, Han Chung Low1, Butch Maulion Magsombol1, Wei Ying Tham1,2, Charles Xian Yang Goh1,2, Colin Jingxian Tan1, Yiu Ming Khor1,2, Sumbul Zaheer1,2, Pushan Bharadwaj1,2, Wanying Xie1,2, David Chee Eng Ng1,2.   

Abstract

The concept of theranostics, where individual patient-level biological information is used to choose the optimal therapy for that individual, has become more popular in the modern era of 'personalised' medicine. With the growth of theranostics, nuclear medicine as a specialty is uniquely poised to grow along with the ever-increasing number of concepts combining imaging and therapy. This special report summarises the status and growth of Theranostic Nuclear Medicine in Singapore. We will cover our experience with the use of radioiodine, radioiodinated metaiodobenzylguanidine, peptide receptor radionuclide therapy, prostate specific membrane antigen radioligand therapy, radium-223 and yttrium-90 selective internal radiation therapy. We also include a section on our radiopharmacy laboratory, crucial to our implementation of theranostic principles. Radionuclide theranostics has seen tremendous growth and we hope to be able to grow alongside to continue to serve the patients in Singapore and in the region.

Entities:  

Keywords:  Lutetium; Radioiodine; Radium; Singapore; Theranostic; Yttrium

Year:  2019        PMID: 31057680      PMCID: PMC6473098          DOI: 10.1007/s13139-019-00580-3

Source DB:  PubMed          Journal:  Nucl Med Mol Imaging        ISSN: 1869-3474


  29 in total

1.  Nothing new under the nuclear sun: towards 80 years of theranostics in nuclear medicine.

Authors:  Frederik A Verburg; Alexander Heinzel; Heribert Hänscheid; Felix M Mottaghy; Markus Luster; Luca Giovanella
Journal:  Eur J Nucl Med Mol Imaging       Date:  2013-11-06       Impact factor: 9.236

2.  Image-guided personalized predictive dosimetry by artery-specific SPECT/CT partition modeling for safe and effective 90Y radioembolization.

Authors:  Yung Hsiang Kao; Andrew Eik Hock Tan; Mark Christiaan Burgmans; Farah Gillian Irani; Li Ser Khoo; Richard Hoau Gong Lo; Kiang Hiong Tay; Bien Soo Tan; Pierce Kah Hoe Chow; David Chee Eng Ng; Anthony Soon Whatt Goh
Journal:  J Nucl Med       Date:  2012-02-17       Impact factor: 10.057

3.  Increased survival with enzalutamide in prostate cancer after chemotherapy.

Authors:  Howard I Scher; Karim Fizazi; Fred Saad; Mary-Ellen Taplin; Cora N Sternberg; Kurt Miller; Ronald de Wit; Peter Mulders; Kim N Chi; Neal D Shore; Andrew J Armstrong; Thomas W Flaig; Aude Fléchon; Paul Mainwaring; Mark Fleming; John D Hainsworth; Mohammad Hirmand; Bryan Selby; Lynn Seely; Johann S de Bono
Journal:  N Engl J Med       Date:  2012-08-15       Impact factor: 91.245

4.  Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial.

Authors:  Johann Sebastian de Bono; Stephane Oudard; Mustafa Ozguroglu; Steinbjørn Hansen; Jean-Pascal Machiels; Ivo Kocak; Gwenaëlle Gravis; Istvan Bodrogi; Mary J Mackenzie; Liji Shen; Martin Roessner; Sunil Gupta; A Oliver Sartor
Journal:  Lancet       Date:  2010-10-02       Impact factor: 79.321

Review 5.  The pathologic classification of neuroendocrine tumors: a review of nomenclature, grading, and staging systems.

Authors:  David S Klimstra; Irvin R Modlin; Domenico Coppola; Ricardo V Lloyd; Saul Suster
Journal:  Pancreas       Date:  2010-08       Impact factor: 3.327

6.  The joint IAEA, EANM, and SNMMI practical guidance on peptide receptor radionuclide therapy (PRRNT) in neuroendocrine tumours.

Authors:  L Bodei; J Mueller-Brand; R P Baum; M E Pavel; D Hörsch; M S O'Dorisio; T M O'Dorisio; T M O'Dorisiol; J R Howe; M Cremonesi; D J Kwekkeboom; John J Zaknun
Journal:  Eur J Nucl Med Mol Imaging       Date:  2013-05       Impact factor: 9.236

7.  ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors: peptide receptor radionuclide therapy with radiolabeled somatostatin analogs.

Authors:  Dik J Kwekkeboom; Eric P Krenning; Rachida Lebtahi; Paul Komminoth; Beata Kos-Kudła; Wouter W de Herder; Ursula Plöckinger
Journal:  Neuroendocrinology       Date:  2009-08-28       Impact factor: 4.914

8.  Alpha emitter radium-223 and survival in metastatic prostate cancer.

Authors:  C Parker; S Nilsson; D Heinrich; S I Helle; J M O'Sullivan; S D Fosså; A Chodacki; P Wiechno; J Logue; M Seke; A Widmark; D C Johannessen; P Hoskin; D Bottomley; N D James; A Solberg; I Syndikus; J Kliment; S Wedel; S Boehmer; M Dall'Oglio; L Franzén; R Coleman; N J Vogelzang; C G O'Bryan-Tear; K Staudacher; J Garcia-Vargas; M Shan; Ø S Bruland; O Sartor
Journal:  N Engl J Med       Date:  2013-07-18       Impact factor: 91.245

9.  Post-radioembolization yttrium-90 PET/CT - part 2: dose-response and tumor predictive dosimetry for resin microspheres.

Authors:  Yung-Hsiang Kao; Jeffrey D Steinberg; Young-Soon Tay; Gabriel Ky Lim; Jianhua Yan; David W Townsend; Charley A Budgeon; Jan A Boucek; Roslyn J Francis; Timothy St Cheo; Mark C Burgmans; Farah G Irani; Richard Hg Lo; Kiang-Hiong Tay; Bien-Soo Tan; Pierce Kh Chow; Somanesan Satchithanantham; Andrew Eh Tan; David Ce Ng; Anthony Sw Goh
Journal:  EJNMMI Res       Date:  2013-07-25       Impact factor: 3.138

10.  Post-radioembolization yttrium-90 PET/CT - part 1: diagnostic reporting.

Authors:  Yung-Hsiang Kao; Jeffrey D Steinberg; Young-Soon Tay; Gabriel Ky Lim; Jianhua Yan; David W Townsend; Angela Takano; Mark C Burgmans; Farah G Irani; Terence Kb Teo; Tow-Non Yeow; Apoorva Gogna; Richard Hg Lo; Kiang-Hiong Tay; Bien-Soo Tan; Pierce Kh Chow; Somanesan Satchithanantham; Andrew Eh Tan; David Ce Ng; Anthony Sw Goh
Journal:  EJNMMI Res       Date:  2013-07-25       Impact factor: 3.138

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