Literature DB >> 3104768

Microinjection of transforming ras protein induces c-fos expression.

D W Stacey, T Watson, H F Kung, T Curran.   

Abstract

Microinjection of p21ras induced c-fos protein accumulation in three types of 3T3 cells. The induction was rapid and efficient and persisted for many hours. In addition, anti-ras antibody dramatically reduced c-fos accumulation after serum stimulation of injected cells. However, cells which expressed p21ras continuously did not maintain a high level of c-fos expression.

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Year:  1987        PMID： 3104768      PMCID： PMC365096          DOI： 10.1128/mcb.7.1.523-527.1987

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  24 in total

1.  Identification of a 39,000-dalton protein in cells transformed by the FBJ murine osteosarcoma virus.

Authors:  T Curran; N M Teich
Journal:  Virology       Date:  1982-01-15       Impact factor: 3.616

2.  Mechanism of activation of a human oncogene.

Authors:  C J Tabin; S M Bradley; C I Bargmann; R A Weinberg; A G Papageorge; E M Scolnick; R Dhar; D R Lowy; E H Chang
Journal:  Nature       Date:  1982-11-11       Impact factor: 49.962

3.  Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor.

Authors:  K Kelly; B H Cochran; C D Stiles; P Leder
Journal:  Cell       Date:  1983-12       Impact factor: 41.582

4.  A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene.

Authors:  E P Reddy; R K Reynolds; E Santos; M Barbacid
Journal:  Nature       Date:  1982-11-11       Impact factor: 49.962

5.  Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences.

Authors:  J Downward; Y Yarden; E Mayes; G Scrace; N Totty; P Stockwell; A Ullrich; J Schlessinger; M D Waterfield
Journal:  Nature       Date:  1984 Feb 9-15       Impact factor: 49.962

6.  Transformation of NIH 3T3 cells by microinjection of Ha-ras p21 protein.

Authors:  D W Stacey; H F Kung
Journal:  Nature       Date:  1984 Aug 9-15       Impact factor: 49.962

7.  Monoclonal antibodies to the p21 products of the transforming gene of Harvey murine sarcoma virus and of the cellular ras gene family.

Authors:  M E Furth; L J Davis; B Fleurdelys; E M Scolnick
Journal:  J Virol       Date:  1982-07       Impact factor: 5.103

8.  Simian sarcoma virus onc gene, v-sis, is derived from the gene (or genes) encoding a platelet-derived growth factor.

Authors:  R F Doolittle; M W Hunkapiller; L E Hood; S G Devare; K C Robbins; S A Aaronson; H N Antoniades
Journal:  Science       Date:  1983-07-15       Impact factor: 47.728

9.  Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus.

Authors:  M D Waterfield; G T Scrace; N Whittle; P Stroobant; A Johnsson; A Wasteson; B Westermark; C H Heldin; J S Huang; T F Deuel
Journal:  Nature       Date:  1983 Jul 7-13       Impact factor: 49.962

Review 10.  Transient induction of c-fos and c-myc in an immediate consequence of growth factor stimulation.

Authors:  T Curran; R Bravo; R Müller
Journal:  Cancer Surv       Date:  1985
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  50 in total

1.  Regulation of collagen I gene expression by ras.

Authors:  J L Slack; M I Parker; V R Robinson; P Bornstein
Journal:  Mol Cell Biol       Date:  1992-10       Impact factor: 4.272

2.  Depletion of c-myc with specific antisense sequences reverses the transformed phenotype in ras oncogene-transformed NIH 3T3 cells.

Authors:  M D Sklar; E Thompson; M J Welsh; M Liebert; J Harney; H B Grossman; M Smith; E V Prochownik
Journal:  Mol Cell Biol       Date:  1991-07       Impact factor: 4.272

3.  Antisense-fos RNA causes partial reversion of the transformed phenotypes induced by the c-Ha-ras oncogene.

Authors:  B J Ledwith; S Manam; A R Kraynak; W W Nichols; M O Bradley
Journal:  Mol Cell Biol       Date:  1990-04       Impact factor: 4.272

4.  Multiple interdependent regulatory sites in the mouse c-fos promoter determine basal level transcription: cell type-specific effects.

Authors:  F C Lucibello; F Ehlert; R Müller
Journal:  Nucleic Acids Res       Date:  1991-07-11       Impact factor: 16.971

5.  Ras proteins are essential and selective for the action of insulin-like growth factor 1 late in the G1 phase of the cell cycle in BALB/c murine fibroblasts.

Authors:  K Lu; J Campisi
Journal:  Proc Natl Acad Sci U S A       Date:  1992-05-01       Impact factor: 11.205

Review 6.  The biochemistry of ras p21.

Authors:  R J Grand; D Owen
Journal:  Biochem J       Date:  1991-11-01       Impact factor: 3.857

7.  Insulin receptor substrate 1 is required for insulin-mediated mitogenic signal transduction.

Authors:  D W Rose; A R Saltiel; M Majumdar; S J Decker; J M Olefsky
Journal:  Proc Natl Acad Sci U S A       Date:  1994-01-18       Impact factor: 11.205

8.  RREB-1, a novel zinc finger protein, is involved in the differentiation response to Ras in human medullary thyroid carcinomas.

Authors:  A Thiagalingam; A De Bustros; M Borges; R Jasti; D Compton; L Diamond; M Mabry; D W Ball; S B Baylin; B D Nelkin
Journal:  Mol Cell Biol       Date:  1996-10       Impact factor: 4.272

9.  Alpha B crystallin accumulation is a specific response to Ha-ras and v-mos oncogene expression in mouse NIH 3T3 fibroblasts.

Authors:  R Klemenz; E Fröhli; A Aoyama; S Hoffmann; R J Simpson; R L Moritz; R Schäfer
Journal:  Mol Cell Biol       Date:  1991-02       Impact factor: 4.272

10.  Cell transformation by c-fos requires an extended period of expression and is independent of the cell cycle.

Authors:  G G Miao; T Curran
Journal:  Mol Cell Biol       Date:  1994-06       Impact factor: 4.272
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