| Literature DB >> 31037355 |
Xin Huang1, Weishan Shi1, Ning Bao1, Chunmei Yu2, Haiying Gu3.
Abstract
The authors describe an electrochemical dopamine sensor that is based on the use of electrochemically co-reduced graphene oxide (Er-GO) and gold nanoparticles (AuNPs) on an indium-tin oxide (ITO) electrode. The synergistic effects of Er-GO and Er-AuNPs promote electron transport in the modified ITO. This results in an excellent performance for voltammetric sensing of dopamine (DA). Under the optimum conditions and a typical working potential of -0.05 V (vs. Ag/AgCl), the ITO electrode has a linear response in the 0.02-200 μM DA concentration range and a low detection limit of 15 nM. The sensor also showed a good selectivity over ascorbic acid and uric acid. The feasibility of the method was studied by analyzing DA in cerebrospinal fluid of rats. Graphical abstract Schematic presentation of one-step electrochemical co-reduction of graphene oxide (GO) and gold nanoparticles (AuNPs) on an ITO electrode for voltammetric sensing of dopamine.Entities:
Keywords: Cerebrospinal fluid; Differential pulse voltammetry; Disposable electrode; Electrochemical sensor; Surface electrochemical co-reduction
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Year: 2019 PMID: 31037355 DOI: 10.1007/s00604-019-3408-7
Source DB: PubMed Journal: Mikrochim Acta ISSN: 0026-3672 Impact factor: 5.833