Literature DB >> 31020032

Transition to outpatient total hip and knee arthroplasty: experience at an academic tertiary care center.

Hrishikesh C Gogineni1, Chancellor F Gray1, Hernan A Prieto1, Justin T Deen1, Andre P Boezaart1,2, Hari K Parvataneni1.   

Abstract

BACKGROUND: Interest in outpatient total hip arthroplasty (THA) and total knee arthroplasty (TKA) has increased recently as part of value-based care and early recovery protocols. Outpatient pathways require significant paradigm shifts, are not used widely, and are mostly implemented at outpatient surgery centers or orthopedic specialty hospitals. In this article, we report on the outcomes of implementation of an outpatient arthroplasty protocol at a tertiary care academic medical center.
METHODS: We performed a retrospective review on a series of 105 consecutive patients who underwent THA or TKA following our newly implemented outpatient arthroplasty protocol. We compared these patients to a group of inpatient arthroplasty patients from the same time period.
RESULTS: Eighty-three of 105 (79%) patients were successfully discharged home on the day of surgery. Successful same-day discharge was predicted by early ambulation (P = .01), TKA over THA (P = .04), and shorter duration of surgery (P = .01). General anesthesia correlated with better early ambulation distances (P = .03) and a lower incidence of urinary retention (P = .049). The outpatient readmission and complication rates were 0.95% and 1.9%, respectively, whereas the matched inpatient rates were 3.7% and 2.9%, respectively.
CONCLUSIONS: Outpatient THA and TKA in a well-selected patient is feasible in an academic multidisciplinary tertiary care hospital, with complication rates approximating inpatient surgery. The findings reported here can be used to further optimize outpatient arthroplasty protocols.

Entities:  

Keywords:  Ambulation; Anesthesia; Outpatient arthroplasty; Rapid recovery; Urinary retention

Year:  2018        PMID: 31020032      PMCID: PMC6470322          DOI: 10.1016/j.artd.2018.10.008

Source DB:  PubMed          Journal:  Arthroplast Today        ISSN: 2352-3441


Introduction

The incidence of primary total hip arthroplasty (THA) and total knee arthroplasty (TKA) has been increasing over the last two decades and is predicted to continue to increase in the future [1], [2], [3]. This expected increase is in both inpatient and outpatient settings, although the majority of the growth is expected in the outpatient setting with only a modest increase in the inpatient setting [4]. This is further supported by the 2018 Outpatient Prospective Payment System rule recently released in November 2017 by the Centers for Medicare and Medicaid Services in which TKA has been removed from the inpatient-only list [5]. Outpatient lower extremity arthroplasty is not a new concept, with published reports dating back over a decade ago [6]. More reports have surfaced recently as interest in outpatient arthroplasty seems to be increasing. This has been driven by multiple factors including the implementation of clinical pathways [7], [8] and rapid-recovery programs [9], [10] which have allowed patients to recover faster, thus reducing length of stay [11], [12], with outpatient surgery being a natural extension of this trend. As part of an institutional, patient-centered quality initiative, we implemented a major redesign of total joint arthroplasty (TJA) care starting in November 2015 [13]. The goal of this initiative was to maintain high standards for patient safety and outcome quality while simultaneously reducing costs. This was a surgeon-led effort with engagement of a multidisciplinary task force consisting of anesthesiologists, acute pain specialists, case management, rehabilitation services, home care companies, hospital administrators, nursing leaders, and hospital quality and data personnel. Extensive changes were made in the preoperative, acute care, and postacute care periods. The redesign was focused on improved pain control, enhanced recovery, reduction in complications and readmissions, and reduced costs. Since its inception, there has been a consistent decrease in the hospital length of stay, reduced complications and readmissions, an increase in the rate of discharge to home, and a decrease in the rate of discharge to skilled nursing facilities [13]. As the redesign progressed, a subset of patients consistently met criteria for discharge on the day of surgery. There was no process in place to facilitate same-day discharge, so the natural evolution of our care redesign was to then develop an outpatient arthroplasty program. It should be noted that our care setting is a large tertiary care academic medical center, unlike the majority of published studies on outpatient arthroplasty programs that typically were performed in ambulatory surgery centers or orthopedic specialty hospitals [14], [15], [16]. Transition to outpatient surgery at orthopedic specialty hospitals (or facilities that have streamlined processes focused on musculoskeletal surgery) has been historically more feasible. There are no studies published on this transition at large multispecialty tertiary care centers where these types of transitions are typically more challenging. We therefore sought to review the feasibility and outcomes related to the implementation of an outpatient arthroplasty protocol in a non-orthopedic multispecialty hospital setting. The primary outcome measure was the rate and predictors of successful same-day discharge to home. Our secondary outcomes were to compare readmissions and complications between the outpatient TJA patients and a loosely matched cohort of inpatients from the same time period.

Material and methods

Study design

After institutional review board approval was obtained, we conducted a retrospective chart review of a consecutive series of patients who were selected for our outpatient arthroplasty protocol. The protocol initiative was first implemented in December 2016, and the institutional review board approval period was from the beginning of the initiative up to March 2018. Surgeries were conducted at our hospital, a 1000-bed tertiary care multispecialty academic medical center. This institution is also the primary referral center for several counties, a level 1 trauma center, and a teaching hospital where resident and fellow education is an important commitment. Data points included success or failure of same-day discharge, type of anesthesia (general vs spinal), method of regional anesthesia, duration of surgery, length of stay in the postanesthesia care unit (PACU) before discharge, ambulation distances (on the first attempt as well as total for the day in PACU) and time to first ambulation in PACU, patient complaints during physical therapy, preoperative hemoglobin levels, urinary retention rates, length of hospital stay for patients who failed to be discharged on the same day, unexpected visits to our after-hour orthopedic clinic and emergency room (ER), and readmissions and complications.

Outpatient protocol

Based on published studies [17], [18], [19], [20], [21], [22], [23], we established social, medical, surgical, and other inclusion criteria, which are summarized in Table 1.
Table 1

Inclusion criteria for outpatient protocol.

Surgical factorsMedical factorsSocial factors
Primary THA or TKAAge < 75 yRAPT > 10
First/second case of the dayBMI < 35Proximity to hospital
No anemia, COPD, CHFPrivate insurance
No cirrhosis
No VTE history
No spinal stenosis
No BPH
No chronic narcotics
Surgeon discretion

BMI, body mass index; BPH, benign prostate hyperplasia; CHF, congestive heart failure; COPD, chronic obstructive pulmonary disease; RAPT, risk assessment and prediction tool; VTE, venous thromboembolism.

Risk assessment and prediction tool is used to predict the discharge destination of patients undergoing elective hip and knee arthroplasties [24].

Inclusion criteria for outpatient protocol. BMI, body mass index; BPH, benign prostate hyperplasia; CHF, congestive heart failure; COPD, chronic obstructive pulmonary disease; RAPT, risk assessment and prediction tool; VTE, venous thromboembolism. Risk assessment and prediction tool is used to predict the discharge destination of patients undergoing elective hip and knee arthroplasties [24]. Structured care pathways were developed for the preoperative, perioperative, and postoperative periods to ensure that care was streamlined and all care providers were coordinated with regard to common goals and expectations. The preoperative pathway first began with careful discussion with the patients about the outpatient surgery protocol. For those patients who had met the inclusion criteria, all were required to also participate in our institutional joint-replacement education program. Finally, patients were evaluated by our preanesthesia clinic, and full instructions regarding perioperative medication use and postoperative pain management and education regarding the continuous and other nerve blocks were provided. All patients were scheduled for the first or second surgical case of the day. Arrangements for outpatient or home physical therapy were made, and standard arthroplasty preoperative and postdischarge instructions were reviewed. A record of all outpatient candidates was maintained by our nurse navigator, and all clinical records were kept in our electronic medical record system (Epic, Verona, WI). The perioperative pathway was broken down into four phases: (1) the block procedure room (BPR), (2) operating room (OR), (3) early PACU, and (4) transition area. In the BPR, all patients underwent insertion of a continuous femoral nerve block (CFNB) using stimulating catheters (Arrow UltraCath; TeleFlex, Richmond, VA) with or without ultrasound assistance, and patients scheduled for TKA received an ultrasound-guided modified infiltration in the Interspace between the Popliteal Artery and the Capsule of the posterior Knee (IPACK) block. The modification involves liberal periarterial injection as well as IPACK of 20 mL of ropivacaine 0.5%. Patients who were scheduled for THA received only a CFNB, and the proceduralists aimed at advancing the catheters toward the lumbar plexus. The posterior capsules of the patients were intraoperatively infiltrated with a mixture of 20 mL of 0.25% bupivacaine and 1:200,000 epinephrine by the surgeon. After placing the CFNB, a bolus of 20 mL of ropivacaine 0.2% was administered through the catheter, which was then connected to a disposable infusion pump (ambIT; Summit Medical Products, Sandy, UT) that was set at a background infusion rate of 5 mL per hour of ropivacaine 0.2%, and a patient-initiated bolus of 5 mL locked out at 60 minutes between boluses or an elastometric disposable pump (AutoFuser; Teleflex, Wayne, PA) that was filled with 500 mL of 0.2% ropivacaine and set at an infusion rate of 5 mL per hour with no patient bolus facility. In the BPR, the patients were also asked to empty their bladders immediately before transfer to the OR. In the OR, the use of indwelling urinary catheters was omitted, and spinal anesthesia or general anesthesia, with or without total intravenous anesthesia, was induced depending on the preferences of the patients, anesthesiologists, or surgeons. No attempt was made to randomize the patients for anesthetic type. Perioperative medications administered are shown in Table 2, and the surgery proceeded in a standard fashion.
Table 2

Perioperative medications.

MedicationDosing information
Preoperative
 Pantoprazole40 mg PO
 Pregabalin (or gabapentin)150-300 mg PO (600-1200 mg PO)
 Tranexamic acid1 g IV before incision and at wound closing
 Continuous femoral nerve block (CFNB)20 mL bolus of 0.5% ropivacaine, infusion of 0.2% ropivacaine at pump settings 5/5/60/1a
 IPACK for TKAs20 mL of 0.5% ropivacaine
Intraoperative
 CFNBInfusion of 0.2% ropivacaine at pump settings 5/5/60/1a
 Spinal anesthesia single shot10-15 mg bupivacaine
 General anesthesia with propofol ± inhalation anesthetic agents
 Fentanyl50-100 mcg IV PRN
 Dexamethasone8 mg IV
 Acetaminophen1000 mg IV
 Ketorolac15-30 mg IV
 Ondansetron4-8 mg IV
Postoperative
 CFNBInfusion of 0.2% ropivacaine at pump settings 5/5/60/1a
 Aspirin81 mg BID PO for 6 weeks for VTE prophylaxis
 Acetaminophen500-1000 mg PO TID as first-line analgesic
 Ibuprofen, naproxen, or celecoxibNSAID of patient’s choice for 2 weeks, if tolerated
 Tramadol50-100 mg PO q8h PRN as first-line analgesic
 Hydrocodone-acetaminophen, 5-325 mgb1-2 tabs PO q4-6h PRN as second-line analgesic
 Oxycodone, 5 mgb1-2 tabs PO q4-6h PRN as second-line analgesic

BID, twice a day; CFNB, continuous femoral nerve block; IPACK, Interspace between the Popliteal Artery and the Capsule of the posterior Knee; IV, intravenous; NSAID, nonsteroidal anti-inflammatory drug; PO, orally; PRN, as needed; TID, three times a day.

Settings for a pain pump device representing 5 mL/h of continuous infusion, 5 mL of a patient demand dose, 60-minute lockout, and one patient demand dose per lockout period.

Hydrocodone-acetaminophen was our preferred prescription, but if a patient had an allergy to or could not tolerate this medication, they were instead prescribed oxycodone.

Perioperative medications. BID, twice a day; CFNB, continuous femoral nerve block; IPACK, Interspace between the Popliteal Artery and the Capsule of the posterior Knee; IV, intravenous; NSAID, nonsteroidal anti-inflammatory drug; PO, orally; PRN, as needed; TID, three times a day. Settings for a pain pump device representing 5 mL/h of continuous infusion, 5 mL of a patient demand dose, 60-minute lockout, and one patient demand dose per lockout period. Hydrocodone-acetaminophen was our preferred prescription, but if a patient had an allergy to or could not tolerate this medication, they were instead prescribed oxycodone. In the PACU, radiographs of the operated joints were obtained, and narcotics were minimized. Before any opioids were considered, a physician of the acute pain service (APS) would see the patient and evaluate the nerve block(s). If any of these were found to be insufficient, corrective actions were taken by the APS physicians which included small-dose single-injection ultrasound-guided subgluteal sciatic nerve blocks in case of severe posterior knee pain (after the sciatic nerve motor function had been evaluated), injecting a 10-mL bolus through the CFNB catheter if the pain was anterior to the hip or knee, or a single-injection ultrasound-guided obturator nerve block in case of posterior hip pain. Ultrasound bladder scans were performed as per our urinary retention protocol (in-and-out catheterization for >800 mL) upon admission to the PACU and thereafter every 2 hours. Within two hours of arrival in the PACU, patients were expected to start working with physical therapy to ambulate. Case managers confirmed discharge needs, durable medical equipment, and home care arrangements. In the transition area, patients received further verbal and written instructions and education on medications, wound care, management of the continuous nerve block site, infusion, and infusion pump, and follow-up instructions were given. The second antibiotic dose was administered, and physical therapy was continued. Patients were discharged and transferred to their vehicle after meeting established criteria: adequate ambulation and pain control, no nausea or vomiting, and normal bladder function. Of note, unlike prior series on outpatient arthroplasty, all surgeries were performed as normal in the usual inpatient ORs, and patients were transferred to the general multispecialty inpatient PACU. There were no changes made to this protocol and no dedicated outpatient ORs, recovery rooms, or staffing. The only change was that once admitted to the PACU, patients worked with physical therapy and were discharged later in the day if criteria were met. If this was not deemed to be safe, they were admitted to the inpatient unit. The postoperative pathway consisted of regular follow-up via telephone (on postoperative day 1, 2, 4, and 7), performed by our nurse navigator. All patients were seen at home on the evening of discharge by a home care nurse. Separate follow-up was also performed by the APS physicians and nurses until discontinuation of the CFNB, which was removed by the home care nurse. Surgeons of our arthroplasty division were available during regular clinic hours if patients needed to be seen unexpectedly. Furthermore, our orthopedic department offered an after-hour orthopedic clinic facility which functioned in the evening hours every day as an orthopedic urgent care and could also be used by our outpatient arthroplasty patients when needed. Follow-up clinic visits were routinely performed at two weeks (for TKAs only), 6 weeks, and 9-12 month points. For our retrospective review, we included all patients who had agreed to participate in the outpatient arthroplasty protocol at their preoperative clinic visit and who were judged by the surgeon to satisfy the inclusion criteria. This cohort included some patients who elected transition to a brief inpatient stay on the day of surgery, using an intention-to-treat type analysis [25], [26].

Inpatient protocol

Inpatient data during the same time frame were accessed for comparison. The outpatient data set was compared to an inpatient data set, which was loosely matched for age, body mass index, and surgeon using Business Objects/SAP suite of software (BusinessObjects XI, San Jose, CA), from our electronic medical record. More stringent matching with additional parameters was not possible due to a limitation of our software. Variables obtained included demographics, hospital length of stay, readmissions, and complications. Insurance data were used to eliminate noncommercial insurance patients (matching the outpatient group) to reduce selection bias and confounding variables.

Statistical analysis

Within our outpatient data set, we performed multivariate regression analyses to test for statistically significant relationships, using IBM SPSS Statistics, version 25 (IBM, Chicago, IL). Coefficients and odds ratios, depending on whether it was a scaled outcome or a categorical outcome, respectively, were obtained for all relationships. To further confirm our statistical findings, simpler one-on-one statistical tests were also used: (1) Chi-square and analysis of variance tests were used for categorical variables; (2) t-tests and Mann-Whitney tests were used for comparing means (for normal and non-normal distributions, respectively); (3) Pearson and Spearman correlation coefficients for testing scaled variables (again for normal and non-normal distributions, respectively).

Results

One hundred and five patients agreed to outpatient THA and TKA at their final preoperative clinic visit. Forty-nine patients (47%) underwent THA, and 56 patients (53%) underwent TKA. Demographic and outcome data for the outpatient group are shown in Table 3. The overall rate of successful discharge to home on the same day in our outpatient arthroplasty group was 79% (83/105).
Table 3

Demographic and outcome data of the outpatient group.

VariableValue
Age in years, mean (range)57.3 (24-80)
Gender, no. of patients, male:female57:48
Body mass index in kg/m2, mean (range)30.0 (18.8-43.3)
Type of surgery, no. of patients, THA:TKA49:56
ASA 1, no. of patients4
ASA 2, no. of patients58
ASA 3, no. of patients40
Anesthesia type, no. of patients, general:spinal43:62
Duration of surgery in minutes, mean (range)106 (70-183)
PACU length of stay in minutes, mean (range)351 (172-613)
Time to first ambulation in minutes, mean (range)186 (16-428)
FAD in feet, mean (range)43 (0-200)
TAD in feet, mean (range)88 (0-290)
Preoperative Hgb in g/dL, mean (range)14.3 (11.4-17.7)
Hospital length of stay in days, mean (range)0.24 (0-2)
Urinary retention, no. of patients23
Orthostatic hypotension, no. of patients13
Successful same-day discharge rate83/105 (79%)

ASA, American Society of Anesthesiologists Physical Status Classification System.

Time to first ambulation is the duration from entering PACU to the first successful ambulation attempt.

First ambulation distance (FAD) is the distance ambulated on the first attempt in PACU.

Total ambulation distance (TAD) is the total distance ambulated throughout the day in PACU.

Preoperative Hgb is the most recent hemoglobin level before surgery.

Demographic and outcome data of the outpatient group. ASA, American Society of Anesthesiologists Physical Status Classification System. Time to first ambulation is the duration from entering PACU to the first successful ambulation attempt. First ambulation distance (FAD) is the distance ambulated on the first attempt in PACU. Total ambulation distance (TAD) is the total distance ambulated throughout the day in PACU. Preoperative Hgb is the most recent hemoglobin level before surgery. Predictors of successful discharge were identified to be type of surgery (THA vs TKA), duration of surgery, and first ambulation distance (FAD) (Table 4). Several metrics were identified which predicted some of these parameters and are summarized in Table 5. No preoperative factors achieved both statistical and clinical significance.
Table 4

Predictors of successful same-day discharge.

Patient dischargedPatient admittedP-value
Type of surgery (% of cases)
 TKA88%12%.04
 THA69%31%
Mean duration of surgery (min)103119.01
Mean first ambulation distance (FAD) in PACU (feet)529.01

Data and statistical results for only the predictors of same-day successful discharge are presented.

FAD is the distance ambulated on first attempt in PACU.

Table 5

Statistically significant results of the outpatient group.

RelationshipP value (odds ratio or coefficient)
Increasing age → decreasing duration of surgery<.01 (−0.98)
Female gender → decreasing duration of surgery.04 (−9.62)
General anesthesia → increased FAD.03 (22.21)
TKA → increased FAD.04 (25.82)
Farther FAD → Farther TAD<.01 (0.70)
Spinal anesthesia → higher urinary retention incidence.049 (3.86)
Higher urinary retention incidence → longer PACU length of stay<.01 (0.36)
Shorter duration of surgery → higher successful discharge rate.01 (1.07)
Farther FAD → higher successful discharge rate.01 (1.05)
TKA → higher successful discharge rate.04 (8.02)

FAD, first ambulation distance; TAD, total ambulation distance.

All of the above relationships are statistically significant.

Odds ratios were used when the dependent variables were categorical data, and coefficients, when the dependent variables were continuous data.

FAD is the distance ambulated on first attempt in PACU.

TAD is total ambulation distance in PACU.

Predictors of successful same-day discharge. Data and statistical results for only the predictors of same-day successful discharge are presented. FAD is the distance ambulated on first attempt in PACU. Statistically significant results of the outpatient group. FAD, first ambulation distance; TAD, total ambulation distance. All of the above relationships are statistically significant. Odds ratios were used when the dependent variables were categorical data, and coefficients, when the dependent variables were continuous data. FAD is the distance ambulated on first attempt in PACU. TAD is total ambulation distance in PACU.

Type of surgery

Patients who underwent TKA had a higher likelihood of discharge than those who underwent THA (88% vs 69%; odds ratio, 8.02; P = .04).

Duration of surgery

The likelihood of same-day discharge increased as the surgical durations decreased (odds ratio, 1.07; P = .01). The duration of surgery itself was predicted by age (coefficient, −0.98; P < .01) and gender (coefficient, −9.62; P = .04), specifically female and older patients tended to have shorter surgeries.

First ambulation distance in PACU

Patients who ambulated further on their first attempt in PACU had a higher likelihood of going home on day zero (odds ratio, 1.05; P = .01). The best predictors of FAD were general anesthesia (coefficient, 22.21; P = .03) and TKA (coefficient, 25.82; P = .04). FAD also was predictive of total ambulation distance (TAD) in PACU (coefficient, 0.70; P < .01), although TAD was not by itself predictive of successful same-day discharge.

Urinary retention

Urinary retention, defined as any patient needing in-and-out catheterization, was more common with spinal anesthesia (odds ratio, 3.86; P = .049) and resulted in longer PACU stays (coefficient, 0.36; P < .01). Based on our postoperative urinary retention protocol, the bladders of five patients (11.6%) had to be emptied by in-and-out catheterization in the patients who received general anesthesia vs 18 patients (29%) who received spinal anesthesia.

PACU stay

The average duration of PACU stay for patients successfully discharged on the same day was 351 minutes, and for the standard inpatient group, it was 236 minutes. The amount of time spent in PACU before ambulation (first ambulation time), for outpatients, was an average of 186 minutes.

Causes of failed discharge and ER visits

The causes of failure of same-day discharge resulting in admission are summarized in Table 6. There were a total of eight visits (7.6%) to the after-hour orthopedic clinic and 12 visits (11.4%) to the ER. The reasons for and timing of ER visits are shown in Table 7.
Table 6

Reasons for admission when unable to discharge same day.

Reason for admissionNumber of times reason was implicated
Orthostatic hypotension8
Patient decision5
Urinary retention4
Nausea4
Leg buckling3
Pain3
Bilateral leg weakness2
Foot drop2
Chest pain1
Pain pump not available1

Some patients stayed for more than one reason.

Table 7

Diagnoses/chief complaints of all ER visits within the outpatient group.

Diagnosis/chief complaintDuration, postoperative
Chest pain6 d
Chest pain7 d
Chest pain2.5 mo
Chest pain2.5 mo
UTI3 d
UTI, pneumonia, UTI8 d, 10 d, 17 d
Urinary retention3 mo
Syncope1 da
Hip dislocation6 wk and again 4 mo
DVT check4 d
Traumatic wound dehiscence1 d, Readmitteda
Allergic dermatitis from tape11 d

DVT, deep vein thrombosis; UTI, urinary tract infection.

ER visits were monitored for up to 90 days.

Only two ER visits were within 48 hours of surgery.

Reasons for admission when unable to discharge same day. Some patients stayed for more than one reason. Diagnoses/chief complaints of all ER visits within the outpatient group. DVT, deep vein thrombosis; UTI, urinary tract infection. ER visits were monitored for up to 90 days. Only two ER visits were within 48 hours of surgery.

Matched inpatient cohort

Data reflecting the comparisons of lengths of hospital stay, readmission rates, and complication rates, between the outpatient and inpatient groups, are shown in Table 8.
Table 8

Comparison of length of stay, complications, and readmissions between the outpatient and matched inpatient groups.

Outpatients (n = 105)Inpatients (n = 136)P value
Age (years, mean)57.353.9.08
Body mass index (kg/m2, mean)30.0330.55.46
Length of stay (days, mean)0.241.53<.01
Readmission rate0.95%3.70%.18
Complication rate1.90%2.90%.61
Comparison of length of stay, complications, and readmissions between the outpatient and matched inpatient groups.

Discussion

Outpatient and early discharge total joint arthroplasty is increasing in the United States as perioperative protocols including early mobilization, multimodal pain management, and regional anesthesia have optimized the postoperative course significantly [6], [7], [8], [9], [10], [11], [12]. Our rate of discharge on the day of surgery (79%) was lower than that reported by previously published studies. Hoffmann et al. published a systematic review showing discharge rates for ten separate studies, with a cumulative successful same-day discharge rate of 94.5% over a total of 1009 patients; however, the majority of these studies were conducted at ambulatory surgery centers or orthopedic specialty hospitals [27]. The setting for our study is a large tertiary care academic medical center, and our PACU is in the same building as our inpatient wards; thus, the trigger for admission may have a much lower threshold at our institution. For example, five patients changed their mind and decided to stay in the hospital but made this decision change at some point after their final preoperative clinic visit. They are included in the study because we followed an intention-to-treat analysis. There was also one admission attributed to the unavailability of a home-going pain pump. If these patients were excluded, our same-day discharge rate would certainly be higher (85%). The distance that patients ambulated on their first attempt, or FAD, was an important predictor of success in the present study and one not found commonly in other similar studies. We found that there were significant associations between FAD and anesthesia type (general vs spinal anesthesia), as well as with type of surgery (THA or TKA). General anesthesia significantly correlated with a farther FAD in PACU. The type of anesthesia, however, did not seem to directly affect the TAD in PACU or TAD. This suggests that the effects of anesthesia on ambulation may be time sensitive, with general anesthesia being more advantageous from an early ambulation standpoint. This early ambulation is certainly not to be discounted, as it suggested successful same-day discharge, with patients who walked farther on their first attempt in PACU, having a higher odds ratio of successful discharge. We should point out that the method of general anesthesia, such as total intravenous anesthesia or inhalational anesthesia, was not consistent, and details on this were not collected for this study. Overall, these patients could ambulate farther on their first attempt than patients who got spinal anesthesia. This is also supported by two previously published randomized controlled trials [28], [29]. The type of surgery, either THA or TKA, was also significantly correlated with FAD, with TKA patients walking farther than THA patients, which then correlated with successful same-day discharge. In addition, the type of surgery itself also significantly correlated directly with successful same-day discharge, with TKA patients having higher odds of same-day discharge than THA patients. Higher same-day discharge rates for TKA over THA patients have been shown in other studies [30]. The type of anesthesia was also significantly correlated with urinary retention, with a higher incidence occurring in patients receiving spinal anesthesia. Urinary retention being associated with spinal anesthesia has been reported in other studies as well [31]. In our study, the presence of urinary retention did not directly correlate significantly with successful same-day discharge, but it did correlate with longer PACU stays. The average PACU stay durations for the outpatients discharged on the same day and for the inpatient group are much longer in our institution than at ambulatory surgery centers performing outpatient arthroplasty [14], [16]. In fact, even our average time to first ambulation (186 minutes) is longer than the average total recovery time in other studies (121-176 minutes) [14], [16]. The long PACU duration in our study might be an inherent characteristic of large academic tertiary care centers with PACUs that cater to all types of surgeries, not only orthopedic. In our inpatient group, physical therapy did not routinely work with patients in PACU and would start mobilization after arrival on the inpatient unit. In our outpatient group, we requested our physical therapists to see all patients in the PACU, which itself was a change from their routine procedure and had inherent delays. Based on these results, having physical therapy treating patients even earlier might further improve outcomes. This change can be slow to implement in large institutions such as ours compared with ambulatory surgery centers. The rate of visits to our hospital ER during the 90-day postoperative period was 11.4%, which is relatively high compared with other published studies [27]. However, most of these ER visits do not seem to be related to the arthroplasty surgery, such as chest pain 2.5 months later or urinary retention 3 months later. There was one patient who went to the ER due to allergic dermatitis from the surgical bandage. This could certainly have been handled at either our regular arthroplasty clinic or our after-hour orthopedic clinic, which indicates to us that there is likely some room for improvement in the education we provide to our patients regarding available resources. It should also be noted that only two of the ER visits were within 48 hours of surgery, which suggests that a standard inpatient stay for patients of the other ER visits may not necessarily have made any difference in those patients eventually going to the ER. Although our ER visit rate is high, it is probably lower than what it might have been if there was no access to our after-hour orthopedic clinic. Readmissions and complications during the 90-day postoperative period were low in our outpatient group and lower than those in the inpatient group (Table 8). The systematic review on outpatients by Hoffmann et al. reports a cumulative readmission rate of 0.89%, a minor complication rate of 1.29%, and a major complication rate of 0.10% [27], which are very similar to our outpatient group, suggesting that the safety profile of our outpatient group has not been compromised. The strengths of our study are that this is a review of a consecutive series of patients through our outpatient arthroplasty protocol. In addition, multiple surgeons participated in the initiative, and the setting was an academic tertiary care hospital. These factors make it applicable to most centers that are considering outpatient surgery and are not orthopedic specialty hospitals. We also compared inpatients during the same time frame to assess for safety and non-inferiority. There are some limitations to our study. The sample size is small, and our statistical tests should be interpreted with that in mind. However, it should be noted that other similar studies have similar sample sizes to ours [14], [15], [16], [32]. We also were not able to easily obtain patient-reported outcomes, which could have been valuable data for comparing before and after surgery status, as well as inpatient and outpatient groups. For our inpatient group, ER visit data and other parameters were not available, resulting in our inability to perform more diligent matching between the inpatient and outpatient cohorts. Finally, we acknowledge the inherent variability in recording and encouraging ambulation distances.

Conclusions

Outpatient THA and TKA are feasible and reproducible in a large multispecialty academic tertiary care hospital and are not inferior to the inpatient setting for TJA. Anesthesia type, duration of surgery, patient factors, and procedure type all predicted success of same-day discharge. Considering that general anesthesia facilitates early ambulation and demonstrates lower rates of urinary retention, it is the authors preferred approach for outpatient TJA. The findings reported here can be used to optimize outpatient arthroplasty protocols at similar medical facilities. Our institution has already integrated the findings outlined here in our updated outpatient arthroplasty protocol.
  31 in total

Review 1.  Intention-to-treat principle.

Authors:  V M Montori; G H Guyatt
Journal:  CMAJ       Date:  2001-11-13       Impact factor: 8.262

2.  Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030.

Authors:  Steven Kurtz; Kevin Ong; Edmund Lau; Fionna Mowat; Michael Halpern
Journal:  J Bone Joint Surg Am       Date:  2007-04       Impact factor: 5.284

3.  Feasibility and safety of performing outpatient unicompartmental knee arthroplasty.

Authors:  Michael B Cross; Richard Berger
Journal:  Int Orthop       Date:  2013-12-13       Impact factor: 3.075

4.  Minimally invasive outpatient total hip arthroplasty: a financial analysis.

Authors:  Kim C Bertin
Journal:  Clin Orthop Relat Res       Date:  2005-06       Impact factor: 4.176

5.  The feasibility and perioperative complications of outpatient knee arthroplasty.

Authors:  Richard A Berger; Sharat K Kusuma; Sheila A Sanders; Elizabeth S Thill; Scott M Sporer
Journal:  Clin Orthop Relat Res       Date:  2009-02-24       Impact factor: 4.176

Review 6.  Rapid recovery protocol for peri-operative care of total hip and total knee arthroplasty patients.

Authors:  Keith R Berend; Adolph V Lombardi; Thomas H Mallory
Journal:  Surg Technol Int       Date:  2004

Review 7.  Effectiveness of clinical pathways for total knee and total hip arthroplasty: literature review.

Authors:  Stephen Kim; Elena Losina; Daniel H Solomon; John Wright; Jeffrey N Katz
Journal:  J Arthroplasty       Date:  2003-01       Impact factor: 4.757

8.  Recovery after total intravenous general anaesthesia or spinal anaesthesia for total knee arthroplasty: a randomized trial.

Authors:  A Harsten; H Kehlet; S Toksvig-Larsen
Journal:  Br J Anaesth       Date:  2013-04-11       Impact factor: 9.166

9.  Day of surgery discharge after unicompartmental knee arthroplasty: an effective perioperative pathway.

Authors:  Joseph S Gondusky; Leera Choi; Naila Khalaf; Jay Patel; Steven Barnett; Robert Gorab
Journal:  J Arthroplasty       Date:  2013-10-31       Impact factor: 4.757

Review 10.  Peri-operative interventions producing better functional outcomes and enhanced recovery following total hip and knee arthroplasty: an evidence-based review.

Authors:  Mazin S Ibrahim; Muhammad A Khan; Ikram Nizam; Fares S Haddad
Journal:  BMC Med       Date:  2013-02-13       Impact factor: 8.775

View more
  10 in total

1.  No Effect of Surgical Approach on Discharge Outcomes in Outpatient Total Hip Arthroplasty.

Authors:  Drake G LeBrun; Scott M LaValva; Bradford S Waddell; David J Mayman; Seth A Jerabek; Michael M Alexiades; Michael P Ast
Journal:  HSS J       Date:  2021-11-08

Review 2.  Educational Intervention in Rehabilitation to Improve Functional Capacity after Hip Arthroplasty: A Scoping Review.

Authors:  Célia Nicolau; Liliana Mendes; Mário Ciríaco; Bruno Ferreira; Cristina Lavareda Baixinho; César Fonseca; Rogério Ferreira; Luís Sousa
Journal:  J Pers Med       Date:  2022-04-19

3.  Readmission, Complication, and Disposition Calculators in Total Joint Arthroplasty: A Systemic Review.

Authors:  Cole M Howie; Simon C Mears; C Lowry Barnes; Jeffrey B Stambough
Journal:  J Arthroplasty       Date:  2020-11-03       Impact factor: 4.757

Review 4.  Safety and efficacy of outpatient hip and knee arthroplasty: a systematic review with meta-analysis.

Authors:  Y F L Bemelmans; M H F Keulen; M Heymans; E H van Haaren; B Boonen; M G M Schotanus
Journal:  Arch Orthop Trauma Surg       Date:  2021-02-15       Impact factor: 2.928

5.  Outpatient total knee arthroplasty: is it economically feasible in the hospital setting?

Authors:  Emmanuel Gibon; Hari K Parvataneni; Hernan A Prieto; Lorrie L Photos; William Z Stone; Chancellor F Gray
Journal:  Arthroplast Today       Date:  2020-03-13

6.  Single-Stage Bilateral Total Hip Arthroplasty in an Ambulatory Surgical Center: A Report of Three Cases.

Authors:  Andrzej Brzezinski; Casey Imbergamo; Matthew Weintraub; Aneesh Patankar; Stephen Kayiaros
Journal:  Arthroplast Today       Date:  2021-03-03

7.  Evaluation of Pericapsular Nerve Group (PENG) Block for Analgesic Effect in Elderly Patients with Femoral Neck Fracture Undergoing Hip Arthroplasty.

Authors:  Hao Hua; Yan Xu; MengLu Jiang; Xu Dai
Journal:  J Healthc Eng       Date:  2022-02-09       Impact factor: 2.682

Review 8.  Outpatient total knee and hip arthroplasty present comparable and even better clinical outcomes than inpatient operation.

Authors:  Song Gong; Yihu Yi; Ruoyu Wang; Lizhi Han; Tianlun Gong; Yuxiang Wang; Wenkai Shao; Yong Feng; Weihua Xu
Journal:  Front Surg       Date:  2022-09-06

9.  Failure to Meet Same-Day Discharge is Not a Predictor of Adverse Outcomes.

Authors:  Vivek Singh; Afamefuna M Nduaguba; William Macaulay; Ran Schwarzkopf; Roy I Davidovitch
Journal:  Arch Orthop Trauma Surg       Date:  2021-06-01       Impact factor: 3.067

Review 10.  Outpatient total knee arthroplasty: is it worth considering?

Authors:  E Carlos Rodríguez-Merchán
Journal:  EFORT Open Rev       Date:  2020-03-02
  10 in total

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