| Literature DB >> 31020032 |
Hrishikesh C Gogineni1, Chancellor F Gray1, Hernan A Prieto1, Justin T Deen1, Andre P Boezaart1,2, Hari K Parvataneni1.
Abstract
BACKGROUND: Interest in outpatient total hip arthroplasty (THA) and total knee arthroplasty (TKA) has increased recently as part of value-based care and early recovery protocols. Outpatient pathways require significant paradigm shifts, are not used widely, and are mostly implemented at outpatient surgery centers or orthopedic specialty hospitals. In this article, we report on the outcomes of implementation of an outpatient arthroplasty protocol at a tertiary care academic medical center.Entities:
Keywords: Ambulation; Anesthesia; Outpatient arthroplasty; Rapid recovery; Urinary retention
Year: 2018 PMID: 31020032 PMCID: PMC6470322 DOI: 10.1016/j.artd.2018.10.008
Source DB: PubMed Journal: Arthroplast Today ISSN: 2352-3441
Inclusion criteria for outpatient protocol.
| Surgical factors | Medical factors | Social factors |
|---|---|---|
| Primary THA or TKA | Age < 75 y | RAPT > 10 |
| First/second case of the day | BMI < 35 | Proximity to hospital |
| No anemia, COPD, CHF | Private insurance | |
| No cirrhosis | ||
| No VTE history | ||
| No spinal stenosis | ||
| No BPH | ||
| No chronic narcotics | ||
| Surgeon discretion |
BMI, body mass index; BPH, benign prostate hyperplasia; CHF, congestive heart failure; COPD, chronic obstructive pulmonary disease; RAPT, risk assessment and prediction tool; VTE, venous thromboembolism.
Risk assessment and prediction tool is used to predict the discharge destination of patients undergoing elective hip and knee arthroplasties [24].
Perioperative medications.
| Medication | Dosing information |
|---|---|
| Preoperative | |
| Pantoprazole | 40 mg PO |
| Pregabalin (or gabapentin) | 150-300 mg PO (600-1200 mg PO) |
| Tranexamic acid | 1 g IV before incision and at wound closing |
| Continuous femoral nerve block (CFNB) | 20 mL bolus of 0.5% ropivacaine, infusion of 0.2% ropivacaine at pump settings 5/5/60/1 |
| IPACK for TKAs | 20 mL of 0.5% ropivacaine |
| Intraoperative | |
| CFNB | Infusion of 0.2% ropivacaine at pump settings 5/5/60/1 |
| Spinal anesthesia single shot | 10-15 mg bupivacaine |
| General anesthesia with propofol ± inhalation anesthetic agents | |
| Fentanyl | 50-100 mcg IV PRN |
| Dexamethasone | 8 mg IV |
| Acetaminophen | 1000 mg IV |
| Ketorolac | 15-30 mg IV |
| Ondansetron | 4-8 mg IV |
| Postoperative | |
| CFNB | Infusion of 0.2% ropivacaine at pump settings 5/5/60/1 |
| Aspirin | 81 mg BID PO for 6 weeks for VTE prophylaxis |
| Acetaminophen | 500-1000 mg PO TID as first-line analgesic |
| Ibuprofen, naproxen, or celecoxib | NSAID of patient’s choice for 2 weeks, if tolerated |
| Tramadol | 50-100 mg PO q8h PRN as first-line analgesic |
| Hydrocodone-acetaminophen, 5-325 mg | 1-2 tabs PO q4-6h PRN as second-line analgesic |
| Oxycodone, 5 mg | 1-2 tabs PO q4-6h PRN as second-line analgesic |
BID, twice a day; CFNB, continuous femoral nerve block; IPACK, Interspace between the Popliteal Artery and the Capsule of the posterior Knee; IV, intravenous; NSAID, nonsteroidal anti-inflammatory drug; PO, orally; PRN, as needed; TID, three times a day.
Settings for a pain pump device representing 5 mL/h of continuous infusion, 5 mL of a patient demand dose, 60-minute lockout, and one patient demand dose per lockout period.
Hydrocodone-acetaminophen was our preferred prescription, but if a patient had an allergy to or could not tolerate this medication, they were instead prescribed oxycodone.
Demographic and outcome data of the outpatient group.
| Variable | Value |
|---|---|
| Age in years, mean (range) | 57.3 (24-80) |
| Gender, no. of patients, male:female | 57:48 |
| Body mass index in kg/m2, mean (range) | 30.0 (18.8-43.3) |
| Type of surgery, no. of patients, THA:TKA | 49:56 |
| ASA 1, no. of patients | 4 |
| ASA 2, no. of patients | 58 |
| ASA 3, no. of patients | 40 |
| Anesthesia type, no. of patients, general:spinal | 43:62 |
| Duration of surgery in minutes, mean (range) | 106 (70-183) |
| PACU length of stay in minutes, mean (range) | 351 (172-613) |
| Time to first ambulation in minutes, mean (range) | 186 (16-428) |
| FAD in feet, mean (range) | 43 (0-200) |
| TAD in feet, mean (range) | 88 (0-290) |
| Preoperative Hgb in g/dL, mean (range) | 14.3 (11.4-17.7) |
| Hospital length of stay in days, mean (range) | 0.24 (0-2) |
| Urinary retention, no. of patients | 23 |
| Orthostatic hypotension, no. of patients | 13 |
| Successful same-day discharge rate | 83/105 (79%) |
ASA, American Society of Anesthesiologists Physical Status Classification System.
Time to first ambulation is the duration from entering PACU to the first successful ambulation attempt.
First ambulation distance (FAD) is the distance ambulated on the first attempt in PACU.
Total ambulation distance (TAD) is the total distance ambulated throughout the day in PACU.
Preoperative Hgb is the most recent hemoglobin level before surgery.
Predictors of successful same-day discharge.
| Patient discharged | Patient admitted | ||
|---|---|---|---|
| Type of surgery (% of cases) | |||
| TKA | 88% | 12% | .04 |
| THA | 69% | 31% | |
| Mean duration of surgery (min) | 103 | 119 | .01 |
| Mean first ambulation distance (FAD) in PACU (feet) | 52 | 9 | .01 |
Data and statistical results for only the predictors of same-day successful discharge are presented.
FAD is the distance ambulated on first attempt in PACU.
Statistically significant results of the outpatient group.
| Relationship | |
|---|---|
| Increasing age → decreasing duration of surgery | <.01 (−0.98) |
| Female gender → decreasing duration of surgery | .04 (−9.62) |
| General anesthesia → increased FAD | .03 (22.21) |
| TKA → increased FAD | .04 (25.82) |
| Farther FAD → Farther TAD | <.01 (0.70) |
| Spinal anesthesia → higher urinary retention incidence | .049 (3.86) |
| Higher urinary retention incidence → longer PACU length of stay | <.01 (0.36) |
| Shorter duration of surgery → higher successful discharge rate | .01 (1.07) |
| Farther FAD → higher successful discharge rate | .01 (1.05) |
| TKA → higher successful discharge rate | .04 (8.02) |
FAD, first ambulation distance; TAD, total ambulation distance.
All of the above relationships are statistically significant.
Odds ratios were used when the dependent variables were categorical data, and coefficients, when the dependent variables were continuous data.
FAD is the distance ambulated on first attempt in PACU.
TAD is total ambulation distance in PACU.
Reasons for admission when unable to discharge same day.
| Reason for admission | Number of times reason was implicated |
|---|---|
| Orthostatic hypotension | 8 |
| Patient decision | 5 |
| Urinary retention | 4 |
| Nausea | 4 |
| Leg buckling | 3 |
| Pain | 3 |
| Bilateral leg weakness | 2 |
| Foot drop | 2 |
| Chest pain | 1 |
| Pain pump not available | 1 |
Some patients stayed for more than one reason.
Diagnoses/chief complaints of all ER visits within the outpatient group.
| Diagnosis/chief complaint | Duration, postoperative |
|---|---|
| Chest pain | 6 d |
| Chest pain | 7 d |
| Chest pain | 2.5 mo |
| Chest pain | 2.5 mo |
| UTI | 3 d |
| UTI, pneumonia, UTI | 8 d, 10 d, 17 d |
| Urinary retention | 3 mo |
| Syncope | 1 d |
| Hip dislocation | 6 wk and again 4 mo |
| DVT check | 4 d |
| Traumatic wound dehiscence | 1 d, Readmitted |
| Allergic dermatitis from tape | 11 d |
DVT, deep vein thrombosis; UTI, urinary tract infection.
ER visits were monitored for up to 90 days.
Only two ER visits were within 48 hours of surgery.
Comparison of length of stay, complications, and readmissions between the outpatient and matched inpatient groups.
| Outpatients (n = 105) | Inpatients (n = 136) | ||
|---|---|---|---|
| Age (years, mean) | 57.3 | 53.9 | .08 |
| Body mass index (kg/m2, mean) | 30.03 | 30.55 | .46 |
| Length of stay (days, mean) | 0.24 | 1.53 | <.01 |
| Readmission rate | 0.95% | 3.70% | .18 |
| Complication rate | 1.90% | 2.90% | .61 |