Martine Hoogman1, Ryan Muetzel1, Joao P Guimaraes1, Elena Shumskaya1, Maarten Mennes1, Marcel P Zwiers1, Neda Jahanshad1, Gustavo Sudre1, Thomas Wolfers1, Eric A Earl1, Juan Carlos Soliva Vila1, Yolanda Vives-Gilabert1, Sabin Khadka1, Stephanie E Novotny1, Catharina A Hartman1, Dirk J Heslenfeld1, Lizanne J S Schweren1, Sara Ambrosino1, Bob Oranje1, Patrick de Zeeuw1, Tiffany M Chaim-Avancini1, Pedro G P Rosa1, Marcus V Zanetti1, Charles B Malpas1, Gregor Kohls1, Georg G von Polier1, Jochen Seitz1, Joseph Biederman1, Alysa E Doyle1, Anders M Dale1, Theo G M van Erp1, Jeffery N Epstein1, Terry L Jernigan1, Ramona Baur-Streubel1, Georg C Ziegler1, Kathrin C Zierhut1, Anouk Schrantee1, Marie F Høvik1, Astri J Lundervold1, Clare Kelly1, Hazel McCarthy1, Norbert Skokauskas1, Ruth L O'Gorman Tuura1, Anna Calvo1, Sara Lera-Miguel1, Rosa Nicolau1, Kaylita C Chantiluke1, Anastasia Christakou1, Alasdair Vance1, Mara Cercignani1, Matt C Gabel1, Philip Asherson1, Sarah Baumeister1, Daniel Brandeis1, Sarah Hohmann1, Ivanei E Bramati1, Fernanda Tovar-Moll1, Andreas J Fallgatter1, Bernd Kardatzki1, Lena Schwarz1, Anatoly Anikin1, Alexandr Baranov1, Tinatin Gogberashvili1, Dmitry Kapilushniy1, Anastasia Solovieva1, Hanan El Marroun1, Tonya White1, Georgii Karkashadze1, Leyla Namazova-Baranova1, Thomas Ethofer1, Paulo Mattos1, Tobias Banaschewski1, David Coghill1, Kerstin J Plessen1, Jonna Kuntsi1, Mitul A Mehta1, Yannis Paloyelis1, Neil A Harrison1, Mark A Bellgrove1, Tim J Silk1, Ana I Cubillo1, Katya Rubia1, Luisa Lazaro1, Silvia Brem1, Susanne Walitza1, Thomas Frodl1, Mariam Zentis1, Francisco X Castellanos1, Yuliya N Yoncheva1, Jan Haavik1, Liesbeth Reneman1, Annette Conzelmann1, Klaus-Peter Lesch1, Paul Pauli1, Andreas Reif1, Leanne Tamm1, Kerstin Konrad1, Eileen Oberwelland Weiss1, Geraldo F Busatto1, Mario R Louza1, Sarah Durston1, Pieter J Hoekstra1, Jaap Oosterlaan1, Michael C Stevens1, J Antoni Ramos-Quiroga1, Oscar Vilarroya1, Damien A Fair1, Joel T Nigg1, Paul M Thompson1, Jan K Buitelaar1, Stephen V Faraone1, Philip Shaw1, Henning Tiemeier1, Janita Bralten1, Barbara Franke1. 1. The Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands (Hoogman, Guimaraes, Shumskaya, Wolfers, Bralten, Franke); the Donders Institute for Brain, Cognition, and Behavior, Radboud University, Nijmegen, the Netherlands (Hoogman, Shumskaya, Mennes, Wolfers, Buitelaar, Bralten, Franke); the Department of Child and Adolescent Psychiatry, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands (Muetzel, El Marroun, White, Tiemeier); the Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands (Muetzel); the Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition, and Behavior, Nijmegen, the Netherlands (Guimaraes, Zwiers, Buitelaar); the Imaging Genetics Center, Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, Marina del Rey, Calif. (Jahanshad, Thompson); National Human Genome Research Institute, Bethesda, Md. (Sudre, Shaw); the Department of Behavioral Neuroscience, Oregon Health and Science University, Portland (Earl, Fair, Nigg); the Department of Psychiatry and Forensic Medicine, Autonomous University of Barcelona, Cerdanyola del Vallès, Spain (Soliva Vila, Ramos-Quiroga, Vilarroya); Instituto ITACA, Polytechnic University of Valencia, Valencia, Spain (Vives-Gilabert); the Olin Neuropsychiatry Research Center, Hartford Hospital, Hartford, Conn. (Khadka, Novotny, Stevens); University of Groningen, University Medical Center Groningen (UMCG), Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE), Groningen, the Netherlands (Hartman, Schweren); Faculty of Behavioral and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam (Heslenfeld); the Department of Child and Adolescent Psychiatry, University of Groningen, University Medical Center Groningen, the Netherlands (Hoekstra); NICHE Lab, Department of Psychiatry, UMC Utrecht Brain Center, Utrecht, the Netherlands (Ambrosino, Oranje, de Zeeuw, Durston); Laboratory of Psychiatric Neuroimaging (LIM-21), Department and Institute of Psychiatry, Faculty of Medicine, University of São Paulo, São Paulo, Brazil (Chaim-Avancini, Rosa, Zanetti, Busatto); the Center for Interdisciplinary Research on Applied Neurosciences (NAPNA), University of São Paulo, São Paulo, Brazil (Chaim-Avancini, Rosa, Zanetti, Busatto); the Developmental Imaging Group, Murdoch Children's Research Institute, Melbourne, Australia (Malpas); the Clinical Outcomes Research Unit (CORe), Department of Medicine, Royal Melbourne Hospital, University of Melbourne, Melbourne, Australia (Malpas); the Melbourne School of Psychological Sciences, University of Melbourne, Melbourne, Australia (Malpas); the Child Neuropsychology Section, University Hospital RWTH Aachen, Aachen, Germany (Kohls, Konrad; Child and Adolescent Psychiatry, University Hospital RWTH Aachen, Aachen, Germany (Polier, Seitz); Institute of Neuroscience and Medicine-Brain and Behavior (INM-7), Research Center Jülich, Jülich, Germany (Polier); the Clinical and Research Programs in Pediatric Psychopharmacology and Adult ADHD, Department of Psychiatry, Massachusetts General Hospital, Boston (Biederman); the Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston (Biederman, Doyle); the Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston (Doyle); the Departments of Neurosciences, Radiology, and Psychiatry and the Center for Multimodal Imaging and Genetics, University of California San Diego (Dale); the Clinical and Translational Neuroscience Laboratory, Department of Psychiatry and Human Behavior, University of California Irvine, Irvine (van Erp); the Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, and the Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati (Epstein, Tamm); the Center for Human Development, University of California San Diego, San Diego (Jernigan); the Division of Molecular Psychiatry, Center of Mental Health, University of Würzburg, Würzburg, Germany (Ziegler, Lesch); the Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centers, Amsterdam (Schrantee, Reneman); the Department of Clinical Medicine, University of Bergen, Bergen, Norway (Høvik); the Division of Psychiatry, Haukeland University Hospital, Bergen, Norway (Høvik, Haavik); the Department of Biological and Medical Psychology, University of Bergen, Bergen, Norway (Lundervold); the K.G. Jebsen Center for Neuropsychiatric Disorders, Department of Biomedicine, University of Bergen, Bergen, Norway (Lundervold, Haavik); the School of Psychology and the Department of Psychiatry, School of Medicine, and the Trinity College Institute of Neuroscience, Trinity College Dublin, Ireland (Kelly); the Department of Child and Adolescent Psychiatry, NYU Langone Medical Center, New York (Kelly, Castellanos, Yoncheva); the Department of Psychiatry, Trinity College Dublin, Ireland (McCarthy, Skokauskas, Frodl); the Centre for Advanced Medical Imaging, St. James's Hospital, Dublin, Ireland (McCarthy); the Center for Child and Adolescent Mental Health, NTNU, Norway, Norwegian University of Science and Technology, Norway (Skokauskas); the Center for MR Research, University Children's Hospital, and the Zurich Center for Integrative Human Physiology, Zurich (O'Gorman Tuura); Magnetic Resonance Image Core Facility, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain (Calvo, Lazaro); the Department of Child and Adolescent Psychiatry and Psychology, Institute of Neurosciences, Hospital Clinic, Barcelona, Spain (Lera-Miguel, Nicolau, Lazaro); the Department of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology, and Neuroscience, King's College London (Chantiluke, Christakou, Cubillo, Rubia); the School of Psychology and Clinical Language Sciences, Centre for Integrative Neuroscience and Neurodynamics, University of Reading, Reading, U.K. (Christakou); the Department of Paediatrics, University of Melbourne, Australia (Vance, Coghill, Silk); the Department of Neuroscience, Brighton and Sussex Medical School, Falmer, Brighton, U.K. (Cercignani, Gabel, Harrison); the Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology, and Neuroscience, King's College London (Asherson, Kuntsi); the Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Medical Faculty Mannheim/Heidelberg University, Mannheim, Germany (Baumeister, Brandeis, Hohmann, Banaschewski); the Department of Child and Adolescent Psychiatry and Psychotherapy, Psychiatric Hospital, University of Zurich, Zurich (Brandeis, Brem, Walitza); the Neuroscience Center Zurich, University of Zurich and ETH Zurich, Zurich (Brandeis, Brem, Walitza); the D'Or Institute for Research and Education, Rio de Janeiro (Bramati, Tovar-Moll, Mattos); the Morphological Sciences Program, Federal University of Rio de Janeiro, Rio de Janeiro (Tovar-Moll); the Department of Psychiatry and Psychotherapy, University Hospital of Tübingen, Tübingen, Germany (Fallgatter, Schwarz, Ethofer); LEAD Graduate School, University of Tübingen, Germany (Fallgatter); the Department of Biomedical Magnetic Resonance, University of Tübingen, Tübingen, Germany (Kardatzki, Ethofer); the National Medical Research Center for Children's Health, Department of Magnetic Resonance Imaging and Densitometry, Moscow (Anikin); the National Medical Research Center for Children's Health, Moscow (Baranov, Solovieva); Russian National Research Medical University, Ministry of Health and Social Development of the Russian Federation, Central Clinical Hospital MSHE, Moscow (Namazova-Baranova); the National Medical Research Center for Children's Health, Laboratory of Neurology and Cognitive Health, Moscow (Gogberashvili, Karkashadze); the National Medical Research Center for Children's Health, Department of Information Technologies, Moscow (Kapilushniy); the Department of Pediatrics, Erasmus MC-Sophia, Rotterdam, the Netherlands (El Marroun); the Department of Psychology, Education, and Child Studies, Erasmus University Rotterdam, Rotterdam, the Netherlands (El Marroun); the Department of Radiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands (White); Federal University of Rio de Janeiro, Rio de Janeiro (Mattos); the Department of Psychiatry, University of Melbourne, Melbourne, Australia (Coghill); the Murdoch Children's Research Institute, Melbourne, Australia (Coghill, Silk); the Division of Neuroscience, University of Dundee, Dundee, U.K. (Coghill); the Child and Adolescent Mental Health Center, Capital Region Copenhagen (Plessen); the Division of Child and Adolescent Psychiatry, Department of Psychiatry, University Hospital Lausanne, Switzerland (Plessen); the Department of Neuroimaging, Institute of Psychiatry, Psychology, and Neuroscience, King's College London (Mehta, Paloyelis); Sussex Partnership NHS Foundation Trust, Swandean, East Sussex, U.K. (Harrison); the Monash Institute for Cognitive and Clinical Neurosciences (MICCN) and the School of Psychological Sciences, Monash University, Melbourne, Australia (Bellgrove); Deakin University, School of Psychology, Geelong, Australia (Silk); the Department of Medicine, University of Barcelona, Barcelona, Spain (Lazaro); the Department of Psychiatry and Psychotherapy, Otto von Guericke University Magdeburg, Germany (Frodl); the German Center for Neurodegenerative Diseases (DZNE), Germany (Frodl); Bezirksklinikum Regensburg, Germany (Zentis); the Nathan Kline Institute for Psychiatric Research, Orangeburg, N.Y. (Castellanos); the Brain Imaging Center, Amsterdam University Medical Centers, Amsterdam (Reneman); the Department of Child and Adolescent Psychiatry, Psychosomatics, and Psychotherapy, Tübingen, Germany (Conzelmann); the Department of Psychology, Biological Psychology, Clinical Psychology, and Psychotherapy, University of Würzburg, Würzburg, Germany (Conzelmann, Pauli, Baur-Streubel, Zierhut); the Laboratory of Psychiatric Neurobiology, Institute of Molecular Medicine, I.M. Sechenov First Moscow State Medical University, Moscow (Lesch); the Department of Neuroscience, School for Mental Health and Neuroscience (MHeNS), Maastricht University, Maastricht, the Netherlands (Lesch); the Department of Psychiatry, Psychosomatic Medicine, and Psychotherapy, University Hospital Frankfurt, Frankfurt, Germany (Reif); JARA Institute Molecular Neuroscience and Neuroimaging (INM-11), Institute for Neuroscience and Medicine, Research Center Jülich, Germany (Konrad); Translational Neuroscience, Child and Adolescent Psychiatry, University Hospital RWTH Aachen, Aachen, Germany (Oberwelland Weiss); Cognitive Neuroscience (INM-3), Institute for Neuroscience and Medicine, Research Center Jülich, Germany (Oberwelland Weiss); the Department of Psychiatry, Faculty of Medicine, University of São Paulo, São Paulo, Brazil (Busatto, Louza); the Clinical Neuropsychology Section, Vrije Universiteit Amsterdam, Amsterdam (Oosterlaan); Emma Children's Hospital Amsterdam Medical Center, Amsterdam (Oosterlaan); the Department of Pediatrics, VU Medical Center, Amsterdam (Oosterlaan); the Department of Psychiatry, Yale University School of Medicine, New Haven, Conn. (Stevens); the Department of Psychiatry, Vall d'Hebron University Hospital, Barcelona, Spain (Ramos-Quiroga); Biomedical Network Research Center on Mental Health (CIBERSAM), Barcelona, Spain (Lazaro, Ramos-Quiroga); Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain (Vilarroya); the Department of Psychiatry, Oregon Health and Science University, Portland (Fair, Nigg); Karakter Child and Adolescent Psychiatry University Center, Nijmegen, the Netherlands (Buitelaar); Departments of Psychiatry and of Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, New York (Faraone); NIHM, Bethesda, Md. (Shaw); the Department of Social and Behavioral Science, Harvard T.H. Chan School of Public Health, Boston (Tiemeier).
Abstract
OBJECTIVE: Neuroimaging studies show structural alterations of various brain regions in children and adults with attention deficit hyperactivity disorder (ADHD), although nonreplications are frequent. The authors sought to identify cortical characteristics related to ADHD using large-scale studies. METHODS: Cortical thickness and surface area (based on the Desikan-Killiany atlas) were compared between case subjects with ADHD (N=2,246) and control subjects (N=1,934) for children, adolescents, and adults separately in ENIGMA-ADHD, a consortium of 36 centers. To assess familial effects on cortical measures, case subjects, unaffected siblings, and control subjects in the NeuroIMAGE study (N=506) were compared. Associations of the attention scale from the Child Behavior Checklist with cortical measures were determined in a pediatric population sample (Generation-R, N=2,707). RESULTS: In the ENIGMA-ADHD sample, lower surface area values were found in children with ADHD, mainly in frontal, cingulate, and temporal regions; the largest significant effect was for total surface area (Cohen's d=-0.21). Fusiform gyrus and temporal pole cortical thickness was also lower in children with ADHD. Neither surface area nor thickness differences were found in the adolescent or adult groups. Familial effects were seen for surface area in several regions. In an overlapping set of regions, surface area, but not thickness, was associated with attention problems in the Generation-R sample. CONCLUSIONS: Subtle differences in cortical surface area are widespread in children but not adolescents and adults with ADHD, confirming involvement of the frontal cortex and highlighting regions deserving further attention. Notably, the alterations behave like endophenotypes in families and are linked to ADHD symptoms in the population, extending evidence that ADHD behaves as a continuous trait in the population. Future longitudinal studies should clarify individual lifespan trajectories that lead to nonsignificant findings in adolescent and adult groups despite the presence of an ADHD diagnosis.
OBJECTIVE: Neuroimaging studies show structural alterations of various brain regions in children and adults with attention deficit hyperactivity disorder (ADHD), although nonreplications are frequent. The authors sought to identify cortical characteristics related to ADHD using large-scale studies. METHODS: Cortical thickness and surface area (based on the Desikan-Killiany atlas) were compared between case subjects with ADHD (N=2,246) and control subjects (N=1,934) for children, adolescents, and adults separately in ENIGMA-ADHD, a consortium of 36 centers. To assess familial effects on cortical measures, case subjects, unaffected siblings, and control subjects in the NeuroIMAGE study (N=506) were compared. Associations of the attention scale from the Child Behavior Checklist with cortical measures were determined in a pediatric population sample (Generation-R, N=2,707). RESULTS: In the ENIGMA-ADHD sample, lower surface area values were found in children with ADHD, mainly in frontal, cingulate, and temporal regions; the largest significant effect was for total surface area (Cohen's d=-0.21). Fusiform gyrus and temporal pole cortical thickness was also lower in children with ADHD. Neither surface area nor thickness differences were found in the adolescent or adult groups. Familial effects were seen for surface area in several regions. In an overlapping set of regions, surface area, but not thickness, was associated with attention problems in the Generation-R sample. CONCLUSIONS: Subtle differences in cortical surface area are widespread in children but not adolescents and adults with ADHD, confirming involvement of the frontal cortex and highlighting regions deserving further attention. Notably, the alterations behave like endophenotypes in families and are linked to ADHD symptoms in the population, extending evidence that ADHD behaves as a continuous trait in the population. Future longitudinal studies should clarify individual lifespan trajectories that lead to nonsignificant findings in adolescent and adult groups despite the presence of an ADHD diagnosis.
Authors: S E Mous; R L Muetzel; H El Marroun; T J C Polderman; A van der Lugt; V W Jaddoe; A Hofman; F C Verhulst; H Tiemeier; D Posthuma; T White Journal: Psychol Med Date: 2014-07-17 Impact factor: 7.723
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Authors: Tonya White; Philip R Jansen; Ryan L Muetzel; Gustavo Sudre; Hanan El Marroun; Henning Tiemeier; Anqi Qiu; Philip Shaw; Andrew M Michael; Frank C Verhulst Journal: Hum Brain Mapp Date: 2017-12-05 Impact factor: 5.038
Authors: David A A Baranger; Lauren R Few; Daniel H Sheinbein; Arpana Agrawal; Thomas F Oltmanns; Annchen R Knodt; Deanna M Barch; Ahmad R Hariri; Ryan Bogdan Journal: Biol Psychiatry Cogn Neurosci Neuroimaging Date: 2020-02-24
Authors: K B Walhovd; I Amlien; A Schrantee; D A Rohani; I Groote; A Bjørnerud; A M Fjell; L Reneman Journal: AJNR Am J Neuroradiol Date: 2020-05 Impact factor: 3.825
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Authors: Yash Patel; Nadine Parker; Jean Shin; Derek Howard; Leon French; Sophia I Thomopoulos; Elena Pozzi; Yoshinari Abe; Christoph Abé; Alan Anticevic; Martin Alda; Andre Aleman; Clara Alloza; Silvia Alonso-Lana; Stephanie H Ameis; Evdokia Anagnostou; Andrew A McIntosh; Celso Arango; Paul D Arnold; Philip Asherson; Francesca Assogna; Guillaume Auzias; Rosa Ayesa-Arriola; Geor Bakker; Nerisa Banaj; Tobias Banaschewski; Cibele E Bandeira; Alexandr Baranov; Núria Bargalló; Claiton H D Bau; Sarah Baumeister; Bernhard T Baune; Mark A Bellgrove; Francesco Benedetti; Alessandro Bertolino; Premika S W Boedhoe; Marco Boks; Irene Bollettini; Caterina Del Mar Bonnin; Tiana Borgers; Stefan Borgwardt; Daniel Brandeis; Brian P Brennan; Jason M Bruggemann; Robin Bülow; Geraldo F Busatto; Sara Calderoni; Vince D Calhoun; Rosa Calvo; Erick J Canales-Rodríguez; Dara M Cannon; Vaughan J Carr; Nicola Cascella; Mara Cercignani; Tiffany M Chaim-Avancini; Anastasia Christakou; David Coghill; Annette Conzelmann; Benedicto Crespo-Facorro; Ana I Cubillo; Kathryn R Cullen; Renata B Cupertino; Eileen Daly; Udo Dannlowski; Christopher G Davey; Damiaan Denys; Christine Deruelle; Annabella Di Giorgio; Erin W Dickie; Danai Dima; Katharina Dohm; Stefan Ehrlich; Benjamin A Ely; Tracy Erwin-Grabner; Thomas Ethofer; Damien A Fair; Andreas J Fallgatter; Stephen V Faraone; Mar Fatjó-Vilas; Jennifer M Fedor; Kate D Fitzgerald; Judith M Ford; Thomas Frodl; Cynthia H Y Fu; Janice M Fullerton; Matt C Gabel; David C Glahn; Gloria Roberts; Tinatin Gogberashvili; Jose M Goikolea; Ian H Gotlib; Roberto Goya-Maldonado; Hans J Grabe; Melissa J Green; Eugenio H Grevet; Nynke A Groenewold; Dominik Grotegerd; Oliver Gruber; Patricia Gruner; Amalia Guerrero-Pedraza; Raquel E Gur; Ruben C Gur; Shlomi Haar; Bartholomeus C M Haarman; Jan Haavik; Tim Hahn; Tomas Hajek; Benjamin J Harrison; Neil A Harrison; Catharina A Hartman; Heather C Whalley; Dirk J Heslenfeld; Derrek P Hibar; Eva Hilland; Yoshiyuki Hirano; Tiffany C Ho; Pieter J Hoekstra; Liesbeth Hoekstra; Sarah Hohmann; L E Hong; Cyril Höschl; Marie F Høvik; Fleur M Howells; Igor Nenadic; Maria Jalbrzikowski; Anthony C James; Joost Janssen; Fern Jaspers-Fayer; Jian Xu; Rune Jonassen; Georgii Karkashadze; Joseph A King; Tilo Kircher; Matthias Kirschner; Kathrin Koch; Peter Kochunov; Gregor Kohls; Kerstin Konrad; Bernd Krämer; Axel Krug; Jonna Kuntsi; Jun Soo Kwon; Mikael Landén; Nils I Landrø; Luisa Lazaro; Irina S Lebedeva; Elisabeth J Leehr; Sara Lera-Miguel; Klaus-Peter Lesch; Christine Lochner; Mario R Louza; Beatriz Luna; Astri J Lundervold; Frank P MacMaster; Luigi A Maglanoc; Charles B Malpas; Maria J Portella; Rachel Marsh; Fiona M Martyn; David Mataix-Cols; Daniel H Mathalon; Hazel McCarthy; Colm McDonald; Genevieve McPhilemy; Susanne Meinert; José M Menchón; Luciano Minuzzi; Philip B Mitchell; Carmen Moreno; Pedro Morgado; Filippo Muratori; Clodagh M Murphy; Declan Murphy; Benson Mwangi; Leila Nabulsi; Akiko Nakagawa; Takashi Nakamae; Leyla Namazova; Janardhanan Narayanaswamy; Neda Jahanshad; Danai D Nguyen; Rosa Nicolau; Ruth L O'Gorman Tuura; Kirsten O'Hearn; Jaap Oosterlaan; Nils Opel; Roel A Ophoff; Bob Oranje; Victor Ortiz García de la Foz; Bronwyn J Overs; Yannis Paloyelis; Christos Pantelis; Mara Parellada; Paul Pauli; Maria Picó-Pérez; Felipe A Picon; Fabrizio Piras; Federica Piras; Kerstin J Plessen; Edith Pomarol-Clotet; Adrian Preda; Olga Puig; Yann Quidé; Joaquim Radua; J Antoni Ramos-Quiroga; Paul E Rasser; Lisa Rauer; Janardhan Reddy; Ronny Redlich; Andreas Reif; Liesbeth Reneman; Jonathan Repple; Alessandra Retico; Vanesa Richarte; Anja Richter; Pedro G P Rosa; Katya K Rubia; Ryota Hashimoto; Matthew D Sacchet; Raymond Salvador; Javier Santonja; Kelvin Sarink; Salvador Sarró; Theodore D Satterthwaite; Akira Sawa; Ulrich Schall; Peter R Schofield; Anouk Schrantee; Jochen Seitz; Mauricio H Serpa; Esther Setién-Suero; Philip Shaw; Devon Shook; Tim J Silk; Kang Sim; Schmitt Simon; Helen Blair Simpson; Aditya Singh; Antonin Skoch; Norbert Skokauskas; Jair C Soares; Noam Soreni; Carles Soriano-Mas; Gianfranco Spalletta; Filip Spaniel; Stephen M Lawrie; Emily R Stern; S Evelyn Stewart; Yoichiro Takayanagi; Henk S Temmingh; David F Tolin; David Tomecek; Diana Tordesillas-Gutiérrez; Michela Tosetti; Anne Uhlmann; Therese van Amelsvoort; Nic J A van der Wee; Steven J A van der Werff; Neeltje E M van Haren; Guido A van Wingen; Alasdair Vance; Javier Vázquez-Bourgon; Daniela Vecchio; Ganesan Venkatasubramanian; Eduard Vieta; Oscar Vilarroya; Yolanda Vives-Gilabert; Aristotle N Voineskos; Henry Völzke; Georg G von Polier; Esther Walton; Thomas W Weickert; Cynthia Shannon Weickert; Andrea S Weideman; Katharina Wittfeld; Daniel H Wolf; Mon-Ju Wu; T T Yang; Kun Yang; Yuliya Yoncheva; Je-Yeon Yun; Yuqi Cheng; Marcus V Zanetti; Georg C Ziegler; Barbara Franke; Martine Hoogman; Jan K Buitelaar; Daan van Rooij; Ole A Andreassen; Christopher R K Ching; Dick J Veltman; Lianne Schmaal; Dan J Stein; Odile A van den Heuvel; Jessica A Turner; Theo G M van Erp; Zdenka Pausova; Paul M Thompson; Tomáš Paus Journal: JAMA Psychiatry Date: 2021-01-01 Impact factor: 21.596
Authors: Premika S W Boedhoe; Daan van Rooij; Martine Hoogman; Jos W R Twisk; Lianne Schmaal; Yoshinari Abe; Pino Alonso; Stephanie H Ameis; Anatoly Anikin; Alan Anticevic; Celso Arango; Paul D Arnold; Philip Asherson; Francesca Assogna; Guillaume Auzias; Tobias Banaschewski; Alexander Baranov; Marcelo C Batistuzzo; Sarah Baumeister; Ramona Baur-Streubel; Marlene Behrmann; Mark A Bellgrove; Francesco Benedetti; Jan C Beucke; Joseph Biederman; Irene Bollettini; Anushree Bose; Janita Bralten; Ivanei E Bramati; Daniel Brandeis; Silvia Brem; Brian P Brennan; Geraldo F Busatto; Sara Calderoni; Anna Calvo; Rosa Calvo; Francisco X Castellanos; Mara Cercignani; Tiffany M Chaim-Avancini; Kaylita C Chantiluke; Yuqi Cheng; Kang Ik K Cho; Anastasia Christakou; David Coghill; Annette Conzelmann; Ana I Cubillo; Anders M Dale; Sara Dallaspezia; Eileen Daly; Damiaan Denys; Christine Deruelle; Adriana Di Martino; Ilan Dinstein; Alysa E Doyle; Sarah Durston; Eric A Earl; Christine Ecker; Stefan Ehrlich; Benjamin A Ely; Jeffrey N Epstein; Thomas Ethofer; Damien A Fair; Andreas J Fallgatter; Stephen V Faraone; Jennifer Fedor; Xin Feng; Jamie D Feusner; Jackie Fitzgerald; Kate D Fitzgerald; Jean-Paul Fouche; Christine M Freitag; Egill A Fridgeirsson; Thomas Frodl; Matt C Gabel; Louise Gallagher; Tinatin Gogberashvili; Ilaria Gori; Patricia Gruner; Deniz A Gürsel; Shlomi Haar; Jan Haavik; Geoffrey B Hall; Neil A Harrison; Catharina A Hartman; Dirk J Heslenfeld; Yoshiyuki Hirano; Pieter J Hoekstra; Marcelo Q Hoexter; Sarah Hohmann; Marie F Høvik; Hao Hu; Chaim Huyser; Neda Jahanshad; Maria Jalbrzikowski; Anthony James; Joost Janssen; Fern Jaspers-Fayer; Terry L Jernigan; Dmitry Kapilushniy; Bernd Kardatzki; Georgii Karkashadze; Norbert Kathmann; Christian Kaufmann; Clare Kelly; Sabin Khadka; Joseph A King; Kathrin Koch; Gregor Kohls; Kerstin Konrad; Masaru Kuno; Jonna Kuntsi; Gerd Kvale; Jun Soo Kwon; Luisa Lázaro; Sara Lera-Miguel; Klaus-Peter Lesch; Liesbeth Hoekstra; Yanni Liu; Christine Lochner; Mario R Louza; Beatriz Luna; Astri J Lundervold; Charles B Malpas; Paulo Marques; Rachel Marsh; Ignacio Martínez-Zalacaín; David Mataix-Cols; Paulo Mattos; Hazel McCarthy; Jane McGrath; Mitul A Mehta; José M Menchón; Maarten Mennes; Mauricio Moller Martinho; Pedro S Moreira; Astrid Morer; Pedro Morgado; Filippo Muratori; Clodagh M Murphy; Declan G M Murphy; Akiko Nakagawa; Takashi Nakamae; Tomohiro Nakao; Leyla Namazova-Baranova; Janardhanan C Narayanaswamy; Rosa Nicolau; Joel T Nigg; Stephanie E Novotny; Erika L Nurmi; Eileen Oberwelland Weiss; Ruth L O'Gorman Tuura; Kirsten O'Hearn; Joseph O'Neill; Jaap Oosterlaan; Bob Oranje; Yannis Paloyelis; Mara Parellada; Paul Pauli; Chris Perriello; John Piacentini; Fabrizio Piras; Federica Piras; Kerstin J Plessen; Olga Puig; J Antoni Ramos-Quiroga; Y C Janardhan Reddy; Andreas Reif; Liesbeth Reneman; Alessandra Retico; Pedro G P Rosa; Katya Rubia; Oana Georgiana Rus; Yuki Sakai; Anouk Schrantee; Lena Schwarz; Lizanne J S Schweren; Jochen Seitz; Philip Shaw; Devon Shook; Tim J Silk; H Blair Simpson; Norbert Skokauskas; Juan Carlos Soliva Vila; Anastasia Solovieva; Noam Soreni; Carles Soriano-Mas; Gianfranco Spalletta; Emily R Stern; Michael C Stevens; S Evelyn Stewart; Gustavo Sudre; Philip R Szeszko; Leanne Tamm; Margot J Taylor; David F Tolin; Michela Tosetti; Fernanda Tovar-Moll; Aki Tsuchiyagaito; Theo G M van Erp; Guido A van Wingen; Alasdair Vance; Ganesan Venkatasubramanian; Oscar Vilarroya; Yolanda Vives-Gilabert; Georg G von Polier; Susanne Walitza; Gregory L Wallace; Zhen Wang; Thomas Wolfers; Yuliya N Yoncheva; Je-Yeon Yun; Marcus V Zanetti; Fengfeng Zhou; Georg C Ziegler; Kathrin C Zierhut; Marcel P Zwiers; Paul M Thompson; Dan J Stein; Jan Buitelaar; Barbara Franke; Odile A van den Heuvel Journal: Am J Psychiatry Date: 2020-06-16 Impact factor: 18.112