Literature DB >> 30993479

Barriers and Facilitators of PrEP Adherence for Young Men and Transgender Women of Color.

Sarah Wood1,2,3, Robert Gross4, Judy A Shea4, José A Bauermeister5, Joshua Franklin6,4, Danielle Petsis6,7, Meghan Swyryn8, Linden Lalley-Chareczko8, Helen C Koenig4,8, Nadia Dowshen6,4,7.   

Abstract

We aimed to discover barriers and facilitators of HIV pre-exposure prophylaxis (PrEP) adherence in young men and transgender women of color who have sex with men (YMSM/TW). Short-term and sustained adherence were measured by urine tenofovir concentration and pharmacy refills, respectively. Optimal adherence was defined as having both urine tenofovir concentration consistent with dose ingestion within 48 h and pharmacy refills consistent with ≥ 4 doses per week use. Participants completed semi-structured interviews exploring adherence barriers and facilitators. Participants (n = 31) were primarily African-American (68%), mean age 22 years (SD: 1.8), and 48% had optimal adherence. Adherence barriers included stigma, health systems inaccessibility, side effects, competing stressors, and low HIV risk perception. Facilitators included social support, health system accessibility, reminders/routines, high HIV risk perception, and personal agency. Our findings identify targets for intervention to improve PrEP adherence in these populations, including augmenting health activation and improving accuracy of HIV risk perception.

Entities:  

Keywords:  Adherence; HIV prevention; Pre-exposure prophylaxis; Social support

Mesh：

Substances：

Year:  2019        PMID： 30993479      PMCID： PMC6790163          DOI： 10.1007/s10461-019-02502-y

Source DB:  PubMed          Journal:  AIDS Behav        ISSN： 1090-7165


  41 in total

1.  Self-Report Measures in the Assessment of Antiretroviral Medication Adherence: Comparison with Medication Possession Ratio and HIV Viral Load.

Authors:  Lassane Kabore; Paul Muntner; Eric Chamot; Anne Zinski; Greer Burkholder; Michael J Mugavero
Journal:  J Int Assoc Provid AIDS Care       Date:  2014-11-23

2.  HIV Pre-exposure Prophylaxis Prescribing Through Telehealth.

Authors:  Joanne D Stekler; Vanessa McMahan; Lark Ballinger; Luis Viquez; Fred Swanson; Jon Stockton; Beth Crutsinger-Perry; David Kern; John D Scott
Journal:  J Acquir Immune Defic Syndr       Date:  2018-04-15       Impact factor: 3.731

3.  Young Transgender Women's Attitudes Toward HIV Pre-exposure Prophylaxis.

Authors:  Sarah M Wood; Susan Lee; Frances K Barg; Marne Castillo; Nadia Dowshen
Journal:  J Adolesc Health       Date:  2017-01-26       Impact factor: 5.012

4.  Safety and Feasibility of Antiretroviral Preexposure Prophylaxis for Adolescent Men Who Have Sex With Men Aged 15 to 17 Years in the United States.

Authors:  Sybil G Hosek; Raphael J Landovitz; Bill Kapogiannis; George K Siberry; Bret Rudy; Brandy Rutledge; Nancy Liu; D Robert Harris; Kathleen Mulligan; Gregory Zimet; Kenneth H Mayer; Peter Anderson; Jennifer J Kiser; Michelle Lally; Jennifer Brothers; Kelly Bojan; Jim Rooney; Craig M Wilson
Journal:  JAMA Pediatr       Date:  2017-11-01       Impact factor: 16.193

5.  Antiretroviral preexposure prophylaxis for heterosexual HIV transmission in Botswana.

Authors:  Michael C Thigpen; Poloko M Kebaabetswe; Lynn A Paxton; Dawn K Smith; Charles E Rose; Tebogo M Segolodi; Faith L Henderson; Sonal R Pathak; Fatma A Soud; Kata L Chillag; Rodreck Mutanhaurwa; Lovemore Ian Chirwa; Michael Kasonde; Daniel Abebe; Evans Buliva; Roman J Gvetadze; Sandra Johnson; Thom Sukalac; Vasavi T Thomas; Clyde Hart; Jeffrey A Johnson; C Kevin Malotte; Craig W Hendrix; John T Brooks
Journal:  N Engl J Med       Date:  2012-07-11       Impact factor: 91.245

6.  Experiences of Anticipated and Enacted Pre-exposure Prophylaxis (PrEP) Stigma Among Latino MSM in Los Angeles.

Authors:  Ronald A Brooks; Amanda Landrian; Omar Nieto; Anne Fehrenbacher
Journal:  AIDS Behav       Date:  2019-07

7.  High Rate of Discontinuation May Diminish PrEP Coverage Among Young Men Who Have Sex with Men.

Authors:  Ethan Morgan; Daniel T Ryan; Michael E Newcomb; Brian Mustanski
Journal:  AIDS Behav       Date:  2018-11

8.  Participant experiences and facilitators and barriers to pill use among men who have sex with men in the iPrEx pre-exposure prophylaxis trial in San Francisco.

Authors:  Hailey J Gilmore; Albert Liu; Kimberly Ann Koester; K Rivet Amico; Vanessa McMahan; Pedro Goicochea; Lorena Vargas; David Lubensky; Susan Buchbinder; Robert Grant
Journal:  AIDS Patient Care STDS       Date:  2013-10       Impact factor: 5.078

9.  Preexposure prophylaxis for HIV infection among African women.

Authors:  Lut Van Damme; Amy Corneli; Khatija Ahmed; Kawango Agot; Johan Lombaard; Saidi Kapiga; Mookho Malahleha; Fredrick Owino; Rachel Manongi; Jacob Onyango; Lucky Temu; Modie Constance Monedi; Paul Mak'Oketch; Mankalimeng Makanda; Ilse Reblin; Shumani Elsie Makatu; Lisa Saylor; Haddie Kiernan; Stella Kirkendale; Christina Wong; Robert Grant; Angela Kashuba; Kavita Nanda; Justin Mandala; Katrien Fransen; Jennifer Deese; Tania Crucitti; Timothy D Mastro; Douglas Taylor
Journal:  N Engl J Med       Date:  2012-07-11       Impact factor: 91.245

10.  Adherence to preexposure prophylaxis: current, emerging, and anticipated bases of evidence.

Authors:  K Rivet Amico; Michael J Stirratt
Journal:  Clin Infect Dis       Date:  2014-07       Impact factor: 9.079
View more
  31 in total

Review 1.  Telemedicine: a solution to disparities in human immunodeficiency virus prevention and pre-exposure prophylaxis uptake, and a framework to scalability and equity.

Authors:  Keith Yiu Kei Wong; Chrysovalantis Stafylis; Jeffrey D Klausner
Journal:  Mhealth       Date:  2020-04-05

2.  Correlates of PrEP Uptake Among Young Sexual Minority Men and Transgender Women in New York City: The Need to Reframe "Risk" Messaging and Normalize Preventative Health.

Authors:  J Jaiswal; C LoSchiavo; S Meanley; K Hascher; A B Cox; K B Dunlap; S N Singer; P N Halkitis
Journal:  AIDS Behav       Date:  2021-04-08

3.  "I Think That I Have a Good Understanding of How to Protect Myself": A Qualitative Study About HIV Risk Perceptions Among Men and Gender Diverse Individuals Who Have Sex With Men.

Authors:  Daniel Resnick; Marilyn M Schapira; Mary E Andrews; Amadi Essoka-Lasenberry; Annet Davis-Vogel; José A Bauermeister; Sarah M Wood
Journal:  AIDS Educ Prev       Date:  2022-02

4.  Characterizing the PrEP Continuum for Black and Latinx Sexual and Gender Minority Youth.

Authors:  Stephen Bonett; Nadia Dowshen; José Bauermeister; Steven Meanley; Andrea L Wirtz; David D Celentano; Noya Galai; Renata Arrington-Sanders
Journal:  AIDS Behav       Date:  2021-09-21

5.  Associations Between Social Support and Social Media Use Among Young Adult Cisgender MSM and Transgender Women Living With HIV.

Authors:  Donald R Gerke; Mary M Step; Dennis Rünger; Jesse B Fletcher; Ronald A Brooks; Nicholas Davis; Kimberly A Kisler; Cathy J Reback
Journal:  Health Promot Pract       Date:  2020-08-06

6.  Family Characteristics in Sex Communication and Social Support: Implications for Emerging Adult Men Who Have Sex with Men's PrEP Engagement.

Authors:  Dalmacio D Flores; Steven P Meanley; Sarah M Wood; Jose A Bauermeister
Journal:  Arch Sex Behav       Date:  2020-03-28

7.  Identifying Opportunities to Discuss Pre-Exposure Prophylaxis During Contraceptive Coaching Discussions With Urban Adolescent Women.

Authors:  Naomi F Fields; Sarah Wood; Christina Amutah; C Alix Timko; Danielle Petsis; Aletha Y Akers
Journal:  J Adolesc Health       Date:  2021-06-05       Impact factor: 5.012

8.  Ending the HIV epidemic in US Latinx sexual and gender minorities.

Authors:  Carlos E Rodriguez-Diaz; Omar Martinez; Sean Bland; Jeffrey S Crowley
Journal:  Lancet       Date:  2021-02-19       Impact factor: 79.321

9.  Sociodemographic Characteristics of HIV Pre-Exposure Prophylaxis Use and Reasons for Nonuse Among Gay, Bisexual, and Other Men Who Have Sex with Men from Three US Cities.

Authors:  Krishna Kiran Kota; Gordon Mansergh; Rob Stephenson; Sabina Hirshfield; Patrick Sullivan
Journal:  AIDS Patient Care STDS       Date:  2021-04-23       Impact factor: 5.078

10.  Prior Sexually Transmitted Infection and Human Immunodeficiency Virus Risk Perception in a Diverse At-Risk Population of Men Who Have Sex with Men and Transgender Individuals.

Authors:  Daniel Resnick; Knashawn Morales; Robert Gross; Danielle Petsis; Danielle Fiore; Annet Davis-Vogel; David Metzger; Ian Frank; Sarah Wood
Journal:  AIDS Patient Care STDS       Date:  2021-01       Impact factor: 5.078
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.