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Literature DB >> 3087053

Paragranuloma is a variant of Hodgkin's disease with predominance of B-cells.

Abstract

Fifteen cases of Hodgkin's disease of nodular and diffuse paragranuloma subtype (nodular and diffuse subtype of lymphocyte predominant type of Hodgkin's disease) were studied by light and electron microscopy, using monoclonal antibodies recognizing T and B-lymphocytes and dendritic reticulum cells. The results were compared with findings on 10 cases of Hodgkin's disease of mixed type with lymphocyte predominance. The present study provides evidence that paragranuloma represents a special variant of Hodgkin's disease different from other subtypes. Paragranuloma is characterized by predominance of B-cells which were demonstrated with a new B cell reagent KiB3 on routinely processed paraffin sections.

Entities: Chemical Disease

Mesh：

Substances：
Antibodies, Monoclonal

Year: 1986 PMID： 3087053 DOI： 10.1007/bf00708326

Source DB: PubMed Journal: Virchows Arch A Pathol Anat Histopathol ISSN： 0174-7398

17 in total

1. [Histological classification and occurrence of Hodgkin's disease].

Authors: K Lennert; N Mohri
Journal: Internist (Berl) Date: 1974-02 Impact factor: 0.743

2. A Hodgkin cell-specific antigen is expressed on a subset of auto- and alloactivated T (helper) lymphoblasts.

Authors: R Andreesen; J Osterholz; G W Löhr; K J Bross
Journal: Blood Date: 1984-06 Impact factor: 22.113

3. An immunohistological study of the cellular constituents of Hodgkin's disease using a monoclonal antibody panel.

Authors: Z Abdulaziz; D Y Mason; H Stein; K C Gatter; J R Nash
Journal: Histopathology Date: 1984-01 Impact factor: 5.087

4. Differential diagnostic features of nodular L & H Hodgkin's disease, including progressive transformation of germinal centers.

Authors: B F Burns; T V Colby; R F Dorfman
Journal: Am J Surg Pathol Date: 1984-04 Impact factor: 6.394

5. Combined immunohistochemical staining for surface IgD and T-lymphocyte subsets with monoclonal antibodies in human tonsils.

Authors: A C Feller; M R Parwaresch; H H Wacker; H J Radzun; K Lennert
Journal: Histochem J Date: 1983-06

6. Peroxidase-positive mononuclear leukocytes as possible precursors of human dendritic reticulum cells.

Authors: M R Parwaresch; H J Radzun; A C Feller; K P Peters; M L Hansmann
Journal: J Immunol Date: 1983-12 Impact factor: 5.422

7. Hodgkin's disease, lymphocyte predominance type, nodular--a distinct entity? Unique staining profile for L&H variants of Reed-Sternberg cells defined by monoclonal antibodies to leukocyte common antigen, granulocyte-specific antigen, and B-cell-specific antigen.

Authors: G S Pinkus; J W Said
Journal: Am J Pathol Date: 1985-01 Impact factor: 4.307

8. Nodular paragranuloma and progressively transformed germinal centers. Ultrastructural and immunohistologic findings.

Authors: S Poppema; E Kaiserling; K Lennert
Journal: Virchows Arch B Cell Pathol Incl Mol Pathol Date: 1979

9. Production of a monoclonal antibody reactive with human dendritic reticulum cells and its use in the immunohistological analysis of lymphoid tissue.

Authors: M Naiem; J Gerdes; Z Abdulaziz; H Stein; D Y Mason
Journal: J Clin Pathol Date: 1983-02 Impact factor: 3.411

10. Clinical features of nodular paragranuloma (Hodgkin's disease, lymphocyte predominance type, nodular).

Authors: M L Hansmann; T Zwingers; A Böske; H Löffler; K Lennert
Journal: J Cancer Res Clin Oncol Date: 1984 Impact factor: 4.553

15 in total

1. Large cell anaplastic lymphoma: evaluation of immunophenotype on paraffin and frozen sections in comparison with ultrastructural features.

Authors: M L Hansmann; C Fellbaum; A Bohm
Journal: Virchows Arch A Pathol Anat Histopathol Date: 1991

2. L and H cells of nodular lymphocyte predominant Hodgkin's disease show immunoglobulin light-chain restriction.

Authors: C Schmid; C Sargent; P G Isaacson
Journal: Am J Pathol Date: 1991-12 Impact factor: 4.307

3. Immunohistochemical differential diagnosis of granulocytic sarcomas and malignant lymphomas on formalin-fixed material.

Authors: C Fellbaum; M L Hansmann
Journal: Virchows Arch A Pathol Anat Histopathol Date: 1990

4. Correlation of content of B cells and Leu7-positive cells with subtype and stage in lymphocyte predominance type Hodgkin's disease.

Authors: M L Hansmann; C Fellbaum; P K Hui; T Zwingers
Journal: J Cancer Res Clin Oncol Date: 1988 Impact factor: 4.553

5. Monoclonal antibody L26: an antibody that is reactive with normal and neoplastic B lymphocytes in routinely fixed and paraffin wax embedded tissues.

Authors: A J Norton; P G Isaacson
Journal: J Clin Pathol Date: 1987-12 Impact factor: 3.411

6. Detailed phenotypic analysis of B-cell lymphoma using a panel of antibodies reactive in routinely fixed wax-embedded tissue.

Authors: A J Norton; P G Isaacson
Journal: Am J Pathol Date: 1987-08 Impact factor: 4.307

7. Lymphocyte predominant Hodgkin's disease of nodular subtype combined with pulmonary lymphoid infiltration and hypogammaglobulinaemia.

Authors: G Li; M L Hansmann
Journal: Virchows Arch A Pathol Anat Histopathol Date: 1989

8. Monocytoid B-cells occurring in Hodgkin's disease.

Authors: L Plank; M L Hansmann; R Fischer
Journal: Virchows Arch Date: 1994 Impact factor: 4.064

9. Diffuse lymphocyte-predominant Hodgkin's disease (diffuse paragranuloma). A variant of the B-cell-derived nodular type.

Authors: M L Hansmann; H Stein; F Dallenbach; C Fellbaum
Journal: Am J Pathol Date: 1991-01 Impact factor: 4.307

10. Absence of bcl-2 major breakpoint region and JH gene rearrangement in lymphocyte predominance Hodgkin's disease. Results of Southern blot analysis and polymerase chain reaction.

Authors: J W Said; A F Sassoon; I P Shintaku; P J Kurtin; G S Pinkus
Journal: Am J Pathol Date: 1991-02 Impact factor: 4.307