Literature DB >> 2035256

Large cell anaplastic lymphoma: evaluation of immunophenotype on paraffin and frozen sections in comparison with ultrastructural features.

M L Hansmann1, C Fellbaum, A Bohm.   

Abstract

Eleven cases of large cell anaplastic lymphoma (T type n = 5, B type n = 4, 0 type n = 2) were investigated using electron microscopy and immunophenotyping on formalin-fixed paraffin sections and frozen sections of fresh tissue, to determine whether morphological criteria exist for the discrimination of T, B, and 0 phenotypes. Tumour cell lineage could not be established from ultrastructural features. On paraffin material monoclonal B-cell markers Ki-B5 and L-26 served as reliable tools for recognizing the B phenotype of large cell anaplastic lymphomas (previously determined on fresh material). whereas monoclonal antibodies MT1 (CD43) and UCHL1 (CD45RO) were of limited value in lineage determination.

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Year:  1991        PMID： 2035256     DOI： 10.1007/bf01605929

Source DB:  PubMed          Journal:  Virchows Arch A Pathol Anat Histopathol        ISSN： 0174-7398


  28 in total

1.  A case of a Ki-1 large cell anaplastic lymphoma with ultrastructural features.

Authors:  B F Burns; C Cripps; I Dardick
Journal:  Hum Pathol       Date:  1989-04       Impact factor: 3.466

2.  High proliferative activity of Reed Sternberg associated antigen Ki-1 positive cells in normal lymphoid tissue.

Authors:  J Gerdes; R Schwarting; H Stein
Journal:  J Clin Pathol       Date:  1986-09       Impact factor: 3.411

Review 3.  Value of CD15 immunostaining in diagnosing Hodgkin's disease: a review of published literature.

Authors:  P A Hall; A J D'Ardenne
Journal:  J Clin Pathol       Date:  1987-11       Impact factor: 3.411

4.  Cellular composition of follicles of follicle centre cell lymphomas in relation to germinal centres of reactive lymph nodes. A morphometrical electromicroscopical study.

Authors:  J P Peters; L H Rademakers; R J de Boer; J A Van Unnik
Journal:  J Pathol       Date:  1987-11       Impact factor: 7.996

5.  Updated Kiel classification for lymphomas.

Authors:  A G Stansfeld; J Diebold; H Noel; Y Kapanci; F Rilke; G Kelényi; C Sundstrom; K Lennert; J A van Unnik; O Mioduszewska
Journal:  Lancet       Date:  1988-02-06       Impact factor: 79.321

6.  Production of a monoclonal antibody specific for Hodgkin and Sternberg-Reed cells of Hodgkin's disease and a subset of normal lymphoid cells.

Authors:  U Schwab; H Stein; J Gerdes; H Lemke; H Kirchner; M Schaadt; V Diehl
Journal:  Nature       Date:  1982-09-02       Impact factor: 49.962

7.  Sinusoidal large cell ("histiocytic") lymphoma.

Authors:  B M Osborne; J J Butler; B Mackay
Journal:  Cancer       Date:  1980-12-01       Impact factor: 6.860

8.  Ki-B5: a monoclonal antibody unrelated to CD45 recognizes normal and neoplastic human B cells in routine paraffin sections.

Authors:  M L Hansmann; H H Wacker; J Gralla; H Lumbeck; M Kossmahl; H J Heidebrecht; H J Radzun; M R Parwaresch
Journal:  Blood       Date:  1991-02-15       Impact factor: 22.113

9.  Hodgkin's disease, lymphocyte predominance type, nodular--further evidence for a B cell derivation. L & H variants of Reed-Sternberg cells express L26, a pan B cell marker.

Authors:  G S Pinkus; J W Said
Journal:  Am J Pathol       Date:  1988-11       Impact factor: 4.307

Review 10.  Lymphoma phenotyping in formalin-fixed and paraffin wax-embedded tissues. I. Range of antibodies and staining patterns.

Authors:  A J Norton; P G Isaacson
Journal:  Histopathology       Date:  1989-05       Impact factor: 5.087
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  1 in total

1.  Primary splenic lymphoma with filiform ultrastructure.

Authors:  U R Suresh; B P Eyden; S S Banerjee; N L Reeve
Journal:  J Clin Pathol       Date:  1993-06       Impact factor: 3.411
  1 in total

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