Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Immunohistochemical differential diagnosis of granulocytic sarcomas and malignant lymphomas on formalin-fixed material.

Literature DB >> 2106752

Immunohistochemical differential diagnosis of granulocytic sarcomas and malignant lymphomas on formalin-fixed material.

Abstract

A panel of monoclonal antibodies (anti-CD45 [common leukocyte antigen], Ki-B3, L26, MT1, UCHL1, anti-CD15 [X-hapten], anti-neutrophil granule protein elastase [NP57]), anti-lysozyme, and the naphthol-ASD-chloroacetate reaction were applied to two cases of granulocytic sarcoma (GS) for evaluation of their utility in differentiating GS from malignant lymphoma. Lysozyme and naphthol-ASD-chloroacetate esterase were found to be the most reliable markers for detection of the myeloid nature of the tumour cells. GS infiltrated solely the mucosa of the nasal cavity in one case, while in the other it involved both the nasal cavity and maxillary sinus with simultaneous eruptions on the skin of the trunk. In both cases, peripheral blood and bone marrow findings were inconspicuous at the time of diagnosis of GS.

Entities: Chemical Disease Gene

Mesh：

Substances：
Fixatives
Formaldehyde

Year: 1990 PMID： 2106752 DOI： 10.1007/bf01605296

Source DB: PubMed Journal: Virchows Arch A Pathol Anat Histopathol ISSN： 0174-7398

24 in total

1. [ON THE SELECTIVE ENZYME-CYTOCHEMICAL DEMONSTRATION OF NEUTROPHILIC MYELOID CELLS AND TISSUE MAST CELLS IN PARAFFIN SECTIONS].

Authors: L D LEDER
Journal: Klin Wochenschr Date: 1964-06-01

2. The demonstration of B-cell, T-cell and myeloid antigens in paraffin sections.

Authors: K P West; A Warford; L Fray; M Allen; A C Campbell; I Lauder
Journal: J Pathol Date: 1986-10 Impact factor: 7.996

3. Use of monoclonal antibody against human neutrophil elastase in normal and leukaemic myeloid cells.

Authors: K A Pulford; W N Erber; J A Crick; I Olsson; K J Micklem; K C Gatter; D Y Mason
Journal: J Clin Pathol Date: 1988-08 Impact factor: 3.411

4. Paraffin section immunohistochemistry. I. Non-Hodgkin's lymphoma.

Authors: P A Hall; A J d'Ardenne; A G Stansfeld
Journal: Histopathology Date: 1988-08 Impact factor: 5.087

5. Granulocytic sarcoma in nonleukemic patients.

Authors: J M Meis; J J Butler; B M Osborne; J T Manning
Journal: Cancer Date: 1986-12-15 Impact factor: 6.860

6. Chloroma (granulocytic sarcoma) without evidence of leukemia: facilitated light microscopic diagnosis.

Authors: K S McCarty; J Wortman; J Daly; R W Rundles; J S Hanker
Journal: Blood Date: 1980-07 Impact factor: 22.113

7. Diagnosis of acute myeloid leukaemia with the use of monoclonal anti-neutrophil elastase (NP57) reactive with routinely processed biopsy samples.

Authors: E Ralfkiaer; K A Pulford; A F Lauritzen; S Avnstrøm; B Guldhammer; D Y Mason
Journal: Histopathology Date: 1989-06 Impact factor: 5.087

Immunohistochemical differential diagnosis of granulocytic sarcomas and malignant lymphomas on formalin-fixed material.

1. [ON THE SELECTIVE ENZYME-CYTOCHEMICAL DEMONSTRATION OF NEUTROPHILIC MYELOID CELLS AND TISSUE MAST CELLS IN PARAFFIN SECTIONS].

2. The demonstration of B-cell, T-cell and myeloid antigens in paraffin sections.

3. Use of monoclonal antibody against human neutrophil elastase in normal and leukaemic myeloid cells.

4. Paraffin section immunohistochemistry. I. Non-Hodgkin's lymphoma.

5. Granulocytic sarcoma in nonleukemic patients.

6. Chloroma (granulocytic sarcoma) without evidence of leukemia: facilitated light microscopic diagnosis.

7. Diagnosis of acute myeloid leukaemia with the use of monoclonal anti-neutrophil elastase (NP57) reactive with routinely processed biopsy samples.

8. Granulocytic sarcoma of the hard palate: report of the first case.

9. Granulocytic sarcoma: a clinicopathologic study of 61 biopsied cases.

10. The immunophenotyping of extramedullary myeloid cell tumors in paraffin-embedded tissue sections.

1. Primary granulocytic sarcoma of the face.

2. Maxillo-ethmoidal chloroma in acute myeloid leukaemia: case report.

3. Cerebrospinal fluid cytology in granulocytic sarcoma with meningeal extension but without bone marrow involvement.