BACKGROUND: Hip fracture is a significant health risk for older adults and malnutrition indicates hip fracture risk. METHODS: We evaluated whether nutrition status could predict clinical outcomes and mortality after hip fracture surgery in older adults. MEDLINE, Cochrane, EMBASE, and Google Scholar databases were searched for studies published until July 1, 2018, in patients with serum albumin or total lymphocyte count (TLC) at admission, nutritional status by Mini Nutritional Assessment (MNA), and in-hospital follow-up. Data extracted were analyzed using random-effects or fixed-effects models. RESULTS: Nineteen studies with 34,363 adults aged 74-85 years receiving hip fracture surgery were eligible for inclusion. Among these studies, 13 were screened for low albumin, 4 were evaluated for TLC, and 4 for nutritional status by MNA. Hypoalbuminemia was significantly associated with higher total mortality and higher risk of in-hospital death (both P < .001). Low TLC and MNA results "at risk of malnutrition" (hazard ratio, 1.67; 95% confidence interval = 1.28-2.18) and "malnourished" nutritional status (hazard ratio, 2.65; 95% CI = 1.81-3.88) also were significantly associated with higher total mortality (all P < .001). CONCLUSION: Low serum albumin level is a sole indicator for increased risk of in-hospital death, postoperative complications, and total mortality after hip fracture surgery in older adults. Low TLC and malnutrition classified by MNA predict increased mortality. These indicators provide valuable prognostic information and routine use may be prudent.
BACKGROUND:Hip fracture is a significant health risk for older adults and malnutrition indicates hip fracture risk. METHODS: We evaluated whether nutrition status could predict clinical outcomes and mortality after hip fracture surgery in older adults. MEDLINE, Cochrane, EMBASE, and Google Scholar databases were searched for studies published until July 1, 2018, in patients with serum albumin or total lymphocyte count (TLC) at admission, nutritional status by Mini Nutritional Assessment (MNA), and in-hospital follow-up. Data extracted were analyzed using random-effects or fixed-effects models. RESULTS: Nineteen studies with 34,363 adults aged 74-85 years receiving hip fracture surgery were eligible for inclusion. Among these studies, 13 were screened for low albumin, 4 were evaluated for TLC, and 4 for nutritional status by MNA. Hypoalbuminemia was significantly associated with higher total mortality and higher risk of in-hospital death (both P < .001). Low TLC and MNA results "at risk of malnutrition" (hazard ratio, 1.67; 95% confidence interval = 1.28-2.18) and "malnourished" nutritional status (hazard ratio, 2.65; 95% CI = 1.81-3.88) also were significantly associated with higher total mortality (all P < .001). CONCLUSION: Low serum albumin level is a sole indicator for increased risk of in-hospital death, postoperative complications, and total mortality after hip fracture surgery in older adults. Low TLC and malnutrition classified by MNA predict increased mortality. These indicators provide valuable prognostic information and routine use may be prudent.
Authors: Michael D Dubé; Christopher A Rothfusz; Ahmed K Emara; Matthew Hadad; Peter Surace; Viktor E Krebs; Robert M Molloy; Nicolas S Piuzzi Journal: Curr Rev Musculoskelet Med Date: 2022-05-03
Authors: Wei-Ti Su; Shao-Chun Wu; Chun-Ying Huang; Sheng-En Chou; Ching-Hua Tsai; Chi Li; Shiun-Yuan Hsu; Ching-Hua Hsieh Journal: Int J Environ Res Public Health Date: 2020-11-30 Impact factor: 3.390
Authors: Cheng-Hsi Yeh; Shao-Chun Wu; Sheng-En Chou; Wei-Ti Su; Ching-Hua Tsai; Chi Li; Shiun-Yuan Hsu; Ching-Hua Hsieh Journal: Int J Environ Res Public Health Date: 2020-12-10 Impact factor: 3.390
Authors: Sandra Eminovic; Gabor Vincze; Doris Eglseer; Regina Riedl; Patrick Sadoghi; Andreas Leithner; Gerwin A Bernhardt Journal: Int Orthop Date: 2020-11-26 Impact factor: 3.075