Sang Min Lee1, Won Chang2, Hyo-Jin Kang3, Su Joa Ahn3, Jeong-Hoon Lee4, Jeong Min Lee5. 1. Department of Radiology, Seoul National University Hospital, Department of Radiology, Hallym University Sacred Heart Hospital, Republic of Korea. jmsh@snu.ac.kr. 2. Departement of Radiology, Seoul National University Bundang Hospital, Republic of Korea. 3. Department of Radiology, Seoul National University Hospital, Republic of Korea. 4. Department of Internal Medicine, Seoul National University Hospital, Republic of Korea. 5. Department of Radiology, Seoul National University Hospital, Department of Radiology, Seoul National University College of Medicine, Institute of Radiation Medicine, Seoul National University Medical Research Center, Republic of Korea.
Abstract
AIMS: To compare the applicability, reliability and stiffness values of four different shear wave elastography (SWE) platforms and to determine the influence of abdominal wall thickness on those of four SWE platforms evaluating liver fibrosis. Material and methods: We used four different SWE platforms: transient elastography (TE), pSWE (S-shear wave), 2D SWE/ SSI (SuperSonic Imagine) and 2D SWE/GE (GE Health care). To identify the effect of abdominal wall thickness, five commercially available liver fibrosis phantoms were covered in 1.3 cm and 2.3 cm thick porcine abdominal walls, respectively. All measurements were performed by three observers. Absolute repeatability of each measurement was evaluated using coefficients of variation (CVs). Applicability rate, CVs and mean stiffness values were compared according to platforms and abdominal wall thickness. RESULTS: Applicability rates were significantly different among the four SWE platforms (p<0.001): 2DSWE/SSI showed the lowest applicability rate (68.9%) compared with the other three platforms (TE, 95.6%, pSWE, 93.3%, 2D SWE/GE, 97.8%) due to higher technical failure rates in phantoms with thick wall. Repeatability was significantly different according to the platform and abdominal wall thickness. Stiffness values did not significantly differ according to abdominal wall thickness, even though the values were significantly different among four platforms in all phantoms. CONCLUSIONS: The applicability, repeatability, and stiffness value were different depending on SWE platforms. Further, the applicability and repeatability would be more affected by abdominal wall thickness. Thus, careful consideration should be given to an appropriate SWE platform, when evaluating liver fibrosis in patients with thick abdominal wall.
AIMS: To compare the applicability, reliability and stiffness values of four different shear wave elastography (SWE) platforms and to determine the influence of abdominal wall thickness on those of four SWE platforms evaluating liver fibrosis. Material and methods: We used four different SWE platforms: transient elastography (TE), pSWE (S-shear wave), 2D SWE/ SSI (SuperSonic Imagine) and 2D SWE/GE (GE Health care). To identify the effect of abdominal wall thickness, five commercially available liver fibrosis phantoms were covered in 1.3 cm and 2.3 cm thick porcine abdominal walls, respectively. All measurements were performed by three observers. Absolute repeatability of each measurement was evaluated using coefficients of variation (CVs). Applicability rate, CVs and mean stiffness values were compared according to platforms and abdominal wall thickness. RESULTS: Applicability rates were significantly different among the four SWE platforms (p<0.001): 2DSWE/SSI showed the lowest applicability rate (68.9%) compared with the other three platforms (TE, 95.6%, pSWE, 93.3%, 2D SWE/GE, 97.8%) due to higher technical failure rates in phantoms with thick wall. Repeatability was significantly different according to the platform and abdominal wall thickness. Stiffness values did not significantly differ according to abdominal wall thickness, even though the values were significantly different among four platforms in all phantoms. CONCLUSIONS: The applicability, repeatability, and stiffness value were different depending on SWE platforms. Further, the applicability and repeatability would be more affected by abdominal wall thickness. Thus, careful consideration should be given to an appropriate SWE platform, when evaluating liver fibrosis in patients with thick abdominal wall.
Authors: Jee Hyeon Lee; Sang Min Lee; Jeong Hee Yoon; Min-Jeong Kim; Hong Il Ha; Sung-Joon Park; Eun Soo Kim; Kwanseop Lee; Jeong Min Lee Journal: Ultrasonography Date: 2020-04-12