Literature DB >> 30632990

Multi-institution Evaluation of Adherence to Comprehensive Postoperative VTE Chemoprophylaxis.

Anthony D Yang1, Daniel Brock Hewitt1,2, Eddie Blay1,3, Lindsey J Kreutzer1, Christopher M Quinn1, Kimberly A Cradock1,4, Vivek Prachand1,5, Karl Y Bilimoria1.   

Abstract

OBJECTIVES: The aims of this study were to: (1) measure the rate of failure to provide defect-free postoperative venous thromboembolism (VTE) chemoprophylaxis, (2) identify reasons for failure to provide defect-free VTE chemoprophylaxis, and (3) examine patient- and hospital-level factors associated with failure. SUMMARY BACKGROUND DATA: Current VTE quality measures are inadequate. VTE outcome measures are invalidated for interhospital comparison by surveillance bias. VTE process measures (e.g., SCIP-VTE-2) do not comprehensively capture failures throughout patients' entire hospitalization.
METHODS: We examined adherence to a novel VTE chemoprophylaxis process measure in patients who underwent colectomies over 18 months at 36 hospitals in a statewide surgical collaborative. This measure assessed comprehensive VTE chemoprophylaxis during each patient's entire hospitalization, including reasons why chemoprophylaxis was not given. Associations of patient and hospital characteristics with measure failure were examined.
RESULTS: The SCIP-VTE-2 hospital-level quality measure identified failures of VTE chemoprophylaxis in 0% to 3% of patients. Conversely, the novel measure unmasked failure to provide defect-free chemoprophylaxis in 18% (736/4086) of colectomies. Reasons for failure included medication not ordered (30.4%), patient refusal (30.3%), incorrect dosage/frequency (8.2%), and patient off-unit (3.4%). Patients were less likely to fail the chemoprophylaxis process measure if treated at nonsafety net hospitals (OR 0.62, 95% CI 0.39-0.99, P = 0.045) or Magnet designated hospitals (OR 0.45, 95% CI 0.29-0.71, P = 0.001).
CONCLUSIONS: In contrast to SCIP-VTE-2, our novel quality measure unmasked VTE chemoprophylaxis failures in 18% of colectomies. Most failures were due to patient refusals or ordering errors. Hospitals should focus improvement efforts on ensuring patients receive VTE prophylaxis throughout their entire hospitalization.

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Year:  2020        PMID: 30632990      PMCID: PMC6904538          DOI: 10.1097/SLA.0000000000003124

Source DB:  PubMed          Journal:  Ann Surg        ISSN: 0003-4932            Impact factor:   13.787


  20 in total

1.  Meta-analysis of low molecular weight heparin in the prevention of venous thromboembolism in general surgery.

Authors:  P Mismetti; S Laporte; J Y Darmon; A Buchmüller; H Decousus
Journal:  Br J Surg       Date:  2001-07       Impact factor: 6.939

Review 2.  Are Higher Hospital Venous Thromboembolism Rates an Indicator of Better Quality?: Evaluation of the Validity of a Hospital Quality Measure.

Authors:  Christina A Minami; Karl Y Bilimoria
Journal:  Adv Surg       Date:  2015

3.  Hidden Barriers to Delivery of Pharmacological Venous Thromboembolism Prophylaxis: The Role of Nursing Beliefs and Practices.

Authors:  Stacy Elder; Deborah B Hobson; Cynthia S Rand; Michael B Streiff; Elliott R Haut; Leigh E Efird; Peggy S Kraus; Christoph U Lehmann; Kenneth M Shermock
Journal:  J Patient Saf       Date:  2016-06       Impact factor: 2.844

4.  Prevention of VTE in nonorthopedic surgical patients: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.

Authors:  Michael K Gould; David A Garcia; Sherry M Wren; Paul J Karanicolas; Juan I Arcelus; John A Heit; Charles M Samama
Journal:  Chest       Date:  2012-02       Impact factor: 9.410

5.  Accurately Measuring Hospital Venous Thromboembolism Prevention Efforts.

Authors:  Anthony D Yang; Karl Y Bilimoria
Journal:  JAMA       Date:  2016-05-17       Impact factor: 56.272

6.  Association between hospital imaging use and venous thromboembolism events rates based on clinical data.

Authors:  Mila H Ju; Jeanette W Chung; Christine V Kinnier; David J Bentrem; David M Mahvi; Clifford Y Ko; Karl Y Bilimoria
Journal:  Ann Surg       Date:  2014-09       Impact factor: 12.969

7.  Optimizing ACS NSQIP modeling for evaluation of surgical quality and risk: patient risk adjustment, procedure mix adjustment, shrinkage adjustment, and surgical focus.

Authors:  Mark E Cohen; Clifford Y Ko; Karl Y Bilimoria; Lynn Zhou; Kristopher Huffman; Xue Wang; Yaoming Liu; Kari Kraemer; Xiangju Meng; Ryan Merkow; Warren Chow; Brian Matel; Karen Richards; Amy J Hart; Justin B Dimick; Bruce L Hall
Journal:  J Am Coll Surg       Date:  2013-04-28       Impact factor: 6.113

8.  Adherence to pharmacological thromboprophylaxis orders in hospitalized patients.

Authors:  John Fanikos; Leslie Ann Stevens; Matthew Labreche; Gregory Piazza; Elaine Catapane; Lena Novack; Samuel Z Goldhaber
Journal:  Am J Med       Date:  2010-06       Impact factor: 4.965

9.  Hospital Characteristics Associated With Penalties in the Centers for Medicare & Medicaid Services Hospital-Acquired Condition Reduction Program.

Authors:  Ravi Rajaram; Jeanette W Chung; Christine V Kinnier; Cynthia Barnard; Sanjay Mohanty; Emily S Pavey; Megan C McHugh; Karl Y Bilimoria
Journal:  JAMA       Date:  2015-07-28       Impact factor: 56.272

Review 10.  Prolonged thromboprophylaxis with low molecular weight heparin for abdominal or pelvic surgery.

Authors:  Morten Schnack Rasmussen; Lars Nannestad Jørgensen; Peer Wille-Jørgensen
Journal:  Cochrane Database Syst Rev       Date:  2009-01-21
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  3 in total

1.  Unbundling Bundles: Evaluating the Association of Individual Colorectal Surgical Site Infection Reduction Bundle Elements on Infection Rates in a Statewide Collaborative.

Authors:  Cary Jo R Schlick; Reiping Huang; Brian C Brajcich; Amy L Halverson; Anthony D Yang; Lindsey Kreutzer; Karl Y Bilimoria; Michael F McGee
Journal:  Dis Colon Rectum       Date:  2022-07-05       Impact factor: 4.412

2.  Natural language processing for the surveillance of postoperative venous thromboembolism.

Authors:  Jianlin Shi; John F Hurdle; Stacy A Johnson; Jeffrey P Ferraro; David E Skarda; Samuel R G Finlayson; Matthew H Samore; Brian T Bucher
Journal:  Surgery       Date:  2021-06-03       Impact factor: 4.348

3.  Association Between Missed Doses of Chemoprophylaxis and VTE Incidence in a Statewide Colectomy Cohort.

Authors:  Rhami Khorfan; Lindsey Kreutzer; Remi Love; Cary Jo R Schlick; Matthew Chia; Karl Y Bilimoria; Anthony D Yang
Journal:  Ann Surg       Date:  2021-04-01       Impact factor: 13.787

  3 in total

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