Literature DB >> 30598555

CRISPR RNA-guided autonomous delivery of Cas9.

Royce A Wilkinson1, Coleman Martin1, Artem A Nemudryi1, Blake Wiedenheft2.   

Abstract

Cas9 is an endonuclease that can be programed to autonomously deliver diverse effectors to specified genetic addresses. High-resolution structures of this protein and its associated CRISPR RNA guide explain the molecular mechanisms of CRISPR-RNA-guided DNA recognition and provide a molecular blueprint that has facilitated structure-guided functional remodeling. Here we retrace events that led from early efforts to understand the central role of Cas9 in CRISPR-mediated adaptive immunity to contemporary efforts aimed at developing and deploying this enzyme for programmable genetic editing.

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Year:  2018        PMID： 30598555      PMCID： PMC7703833          DOI： 10.1038/s41594-018-0173-y

Source DB:  PubMed          Journal:  Nat Struct Mol Biol        ISSN： 1545-9985            Impact factor:   15.369


  103 in total

1.  Synthetic CRISPR RNA-Cas9-guided genome editing in human cells.

Authors:  Meghdad Rahdar; Moira A McMahon; Thazha P Prakash; Eric E Swayze; C Frank Bennett; Don W Cleveland
Journal:  Proc Natl Acad Sci U S A       Date:  2015-11-16       Impact factor: 11.205

2.  Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease.

Authors:  Cem Kuscu; Sevki Arslan; Ritambhara Singh; Jeremy Thorpe; Mazhar Adli
Journal:  Nat Biotechnol       Date:  2014-05-18       Impact factor: 54.908

3.  Structural Basis for the Altered PAM Specificities of Engineered CRISPR-Cas9.

Authors:  Seiichi Hirano; Hiroshi Nishimasu; Ryuichiro Ishitani; Osamu Nureki
Journal:  Mol Cell       Date:  2016-03-17       Impact factor: 17.970

4.  CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering.

Authors:  Prashant Mali; John Aach; P Benjamin Stranges; Kevin M Esvelt; Mark Moosburner; Sriram Kosuri; Luhan Yang; George M Church
Journal:  Nat Biotechnol       Date:  2013-08-01       Impact factor: 54.908

5.  Manipulation of nuclear architecture through CRISPR-mediated chromosomal looping.

Authors:  Stefanie L Morgan; Natasha C Mariano; Abel Bermudez; Nicole L Arruda; Fangting Wu; Yunhai Luo; Gautam Shankar; Lin Jia; Huiling Chen; Ji-Fan Hu; Andrew R Hoffman; Chiao-Chain Huang; Sharon J Pitteri; Kevin C Wang
Journal:  Nat Commun       Date:  2017-07-13       Impact factor: 14.919

6.  Synthetically modified guide RNA and donor DNA are a versatile platform for CRISPR-Cas9 engineering.

Authors:  Kunwoo Lee; Vanessa A Mackley; Anirudh Rao; Anthony T Chong; Mark A Dewitt; Jacob E Corn; Niren Murthy
Journal:  Elife       Date:  2017-05-02       Impact factor: 8.140

7.  Locus-specific histone deacetylation using a synthetic CRISPR-Cas9-based HDAC.

Authors:  Deborah Y Kwon; Ying-Tao Zhao; Janine M Lamonica; Zhaolan Zhou
Journal:  Nat Commun       Date:  2017-05-12       Impact factor: 14.919

8.  CRISPR RNA-guided activation of endogenous human genes.

Authors:  Morgan L Maeder; Samantha J Linder; Vincent M Cascio; Yanfang Fu; Quan H Ho; J Keith Joung
Journal:  Nat Methods       Date:  2013-07-25       Impact factor: 28.547

9.  RNA-guided gene activation by CRISPR-Cas9-based transcription factors.

Authors:  Pablo Perez-Pinera; D Dewran Kocak; Christopher M Vockley; Andrew F Adler; Ami M Kabadi; Lauren R Polstein; Pratiksha I Thakore; Katherine A Glass; David G Ousterout; Kam W Leong; Farshid Guilak; Gregory E Crawford; Timothy E Reddy; Charles A Gersbach
Journal:  Nat Methods       Date:  2013-07-25       Impact factor: 28.547

10.  High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.

Authors:  Benjamin P Kleinstiver; Vikram Pattanayak; Michelle S Prew; Shengdar Q Tsai; Nhu T Nguyen; Zongli Zheng; J Keith Joung
Journal:  Nature       Date:  2016-01-06       Impact factor: 49.962
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  9 in total

Review 1.  Allosteric regulation of CRISPR-Cas9 for DNA-targeting and cleavage.

Authors:  Zhicheng Zuo; Jin Liu
Journal:  Curr Opin Struct Biol       Date:  2020-02-18       Impact factor: 6.809

2.  Cas9 slide-and-seek for phage defense and genome engineering.

Authors:  Andrew Santiago-Frangos; Tanner Wiegand; Blake Wiedenheft
Journal:  EMBO J       Date:  2019-02-07       Impact factor: 11.598

Review 3.  Liposomal delivery of CRISPR/Cas9.

Authors:  Shuai Zhen; Xu Li
Journal:  Cancer Gene Ther       Date:  2019-11-02       Impact factor: 5.987

Review 4.  CRISPR Technology in Cancer Diagnosis and Treatment: Opportunities and Challenges.

Authors:  Behrouz Shademan; Sepideh Masjedi; Vahidreza Karamad; Alireza Isazadeh; Fatma Sogutlu; Mohammad Hosein Saeedi Rad; Alireza Nourazarian
Journal:  Biochem Genet       Date:  2022-01-29       Impact factor: 2.220

5.  Cryo-EM structures reveal coordinated domain motions that govern DNA cleavage by Cas9.

Authors:  Xing Zhu; Ryan Clarke; Anupama K Puppala; Sagar Chittori; Alan Merk; Bradley J Merrill; Miljan Simonović; Sriram Subramaniam
Journal:  Nat Struct Mol Biol       Date:  2019-07-08       Impact factor: 15.369

Review 6.  Genome editing technologies: CRISPR, LEAPER, RESTORE, ARCUT, SATI, and RESCUE.

Authors:  Senay Görücü Yilmaz
Journal:  EXCLI J       Date:  2021-01-04       Impact factor: 4.068

7.  Sumoylation of Cas9 at lysine 848 regulates protein stability and DNA binding.

Authors:  Tunahan Ergünay; Özgecan Ayhan; Arda B Celen; Panagiota Georgiadou; Emre Pekbilir; Yusuf T Abaci; Duygu Yesildag; Mandy Rettel; Ulduz Sobhiafshar; Anna Ogmen; Nc Tolga Emre; Umut Sahin
Journal:  Life Sci Alliance       Date:  2022-01-12

8.  Effects of CRISPR/Cas9-mediated stearoyl-Coenzyme A desaturase 1 knockout on mouse embryo development and lipid synthesis.

Authors:  Huibin Tian; Huimin Niu; Jun Luo; Weiwei Yao; Wenchang Gao; Yang Wen; Min Cheng; Anmin Lei; Jinlian Hua
Journal:  PeerJ       Date:  2022-09-14       Impact factor: 3.061

Review 9.  CRISPR/Cas9 in Cancer Immunotherapy: Animal Models and Human Clinical Trials.

Authors:  Khalil Khalaf; Krzysztof Janowicz; Marta Dyszkiewicz-Konwińska; Greg Hutchings; Claudia Dompe; Lisa Moncrieff; Maurycy Jankowski; Marta Machnik; Urszula Oleksiewicz; Ievgeniia Kocherova; Jim Petitte; Paul Mozdziak; Jamil A Shibli; Dariusz Iżycki; Małgorzata Józkowiak; Hanna Piotrowska-Kempisty; Mariusz T Skowroński; Paweł Antosik; Bartosz Kempisty
Journal:  Genes (Basel)       Date:  2020-08-11       Impact factor: 4.096
  9 in total

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