| Literature DB >> 30594028 |
Lalit Mohan Nainwal1, Sharba Tasneem1, Wasim Akhtar1, Garima Verma1, Mohammed Faraz Khan1, Suhel Parvez2, Mohammad Shaquiquzzaman1, Mymoona Akhter1, Mohammad Mumtaz Alam3.
Abstract
The quinoline core possesses a vast number of biological activities such as anticancer, antimalarial, antimicrobial, antifungal, antitubercular and antileishmanial. The conventional classical synthetic methods require the use of expensive and harsh conditions such as high temperature. Currently the scientific communities are searching new methodology to eliminate the use of chemicals, solvents and catalysts, which are hazardous to human health as well as to environment. This review provides a concise overview of new dimensions of green chemistry approaches in designing quinoline scaffold that would encourage the researchers towards green chemistry as well as future application of these greener, non-toxic, environment friendly methods in designing quinoline scaffold.Entities:
Keywords: Friedländer reaction; Green chemistry; Microwave irradiation; Multicomponent reactions; Quinolines
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Year: 2018 PMID: 30594028 DOI: 10.1016/j.ejmech.2018.11.026
Source DB: PubMed Journal: Eur J Med Chem ISSN: 0223-5234 Impact factor: 6.514