Literature DB >> 3057385

Deleterious mutations and the evolution of sexual reproduction.

A S Kondrashov1.   

Abstract

The origin and maintenance of sexual reproduction continues to be an important problem in evolutionary biology. If the deleterious mutation rate per genome per generation is greater than 1, then the greater efficiency of selection against these mutations in sexual populations may be responsible for the evolution of sex and related phenomena. In modern human populations detrimental mutations with small individual effects are probably accumulating faster than they are being eliminated by selection.

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Year:  1988        PMID: 3057385     DOI: 10.1038/336435a0

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  296 in total

1.  The coevolution of cell senescence and diploid sexual reproduction in unicellular organisms.

Authors:  Y Cui; R S Chen; W H Wong
Journal:  Proc Natl Acad Sci U S A       Date:  2000-03-28       Impact factor: 11.205

2.  Pervasive compensatory adaptation in Escherichia coli.

Authors:  F B Moore; D E Rozen; R E Lenski
Journal:  Proc Biol Sci       Date:  2000-03-07       Impact factor: 5.349

3.  Estimation of parameters of deleterious mutations in partial selfing or partial outcrossing populations and in nonequilibrium populations.

Authors:  J Li; H W Deng
Journal:  Genetics       Date:  2000-04       Impact factor: 4.562

4.  Coevolution of costly mate choice and condition-dependent display of good genes.

Authors:  David Houle; Alexey S Kondrashov
Journal:  Proc Biol Sci       Date:  2002-01-07       Impact factor: 5.349

5.  Evolutionary route to diploidy and sex.

Authors:  E Tüzel; V Sevim; A Erzan
Journal:  Proc Natl Acad Sci U S A       Date:  2001-11-06       Impact factor: 11.205

6.  Recessive mutations and the maintenance of sex in structured populations.

Authors:  A F Agrawal; J R Chasnov
Journal:  Genetics       Date:  2001-06       Impact factor: 4.562

7.  Rates of nucleotide substitution in sexual and anciently asexual rotifers.

Authors:  D B Mark Welch; M S Meselson
Journal:  Proc Natl Acad Sci U S A       Date:  2001-05-29       Impact factor: 11.205

8.  Epistasis and the mutation load: a measurement-theoretical approach.

Authors:  T F Hansen; G P Wagner
Journal:  Genetics       Date:  2001-05       Impact factor: 4.562

9.  The evolution of recombination in a heterogeneous environment.

Authors:  T Lenormand; S P Otto
Journal:  Genetics       Date:  2000-09       Impact factor: 4.562

10.  The maintenance of sex in parasites.

Authors:  Alison P Galvani; Ronald M Coleman; Neil M Ferguson
Journal:  Proc Biol Sci       Date:  2003-01-07       Impact factor: 5.349

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