Literature DB >> 30542834

"Closing the Gap": Provider Recommendations for Implementing Birth Point of Care HIV Testing.

Catherine Wexler1, Yvonne Kamau2, Ritika Halder2, Melinda Brown1, May Maloba3, Natabhona Mabachi1, Matthew Sandbulte4, Brad Gautney5, Kathy Goggin6,7, Thomas Odeny8,9, Sarah Finocchario-Kessler1.   

Abstract

Delays in traditional HIV DNA PCR testing for early infant diagnosis (EID) at 6 weeks of age result in late antiretroviral treatment (ART). Birth point of care (POC) testing is an emerging strategy with the potential to streamline EID services. We elicited providers' recommendations for introducing birth POC testing to guide strategies in Kenya and similar settings. We conducted formative interviews with 26 EID providers from four Kenyan hospitals prior to POC implementation. Providers discussed the need for comprehensive training, covering both EID and POC-specific topics for all key personnel. Providers highlighted equipment considerations, such as protocols for maintenance and safe storage. Providers emphasized the need for maternal counseling to ensure patient acceptance and most agreed that specimen collection for birth POC testing should occur in the maternity department and supported a multidisciplinary approach. Though most providers supported ART initiation based on a positive birth POC result, a few expressed concerns with result validity. To maximize implementation success, provider training, equipment security, maternal counseling, and logistics of testing must be planned and communicated to providers.

Entities:  

Keywords:  Birth testing; Early infant diagnosis; HIV testing; Implementation recommendations; Point of care

Mesh:

Substances:

Year:  2019        PMID: 30542834     DOI: 10.1007/s10461-018-2363-3

Source DB:  PubMed          Journal:  AIDS Behav        ISSN: 1090-7165


  5 in total

1.  ART Initiation for Infants Diagnosed With HIV Through Point of Care and Conventional Polymerase Chain Reaction Testing in Kenya: A Case Series.

Authors:  Catherine Wexler; May Maloba; Kathy Goggin; Shadrack Babu Kale; Nicodemus Maosa; Elizabeth Muchoki; Melinda Brown; Brad Gautney; Sarah Finocchario-Kessler
Journal:  Pediatr Infect Dis J       Date:  2021-04-01       Impact factor: 3.806

2.  Programmatic evaluation of feasibility and efficiency of at birth and 6-week, point of care HIV testing in Kenyan infant.

Authors:  Catherine Wexler; Niaman Nazir; May Maloba; Melinda Brown; Kathy Goggin; Brad Gautney; Nicodemus Maosa; Shadrack Babu; Elizabeth Muchoki; Natabhona Mabachi; Raphael Lwembe; Sarah Finocchario-Kessler
Journal:  PLoS One       Date:  2020-10-09       Impact factor: 3.240

Review 3.  Accelerating progress towards the elimination of mother-to-child transmission of HIV: a narrative review.

Authors:  Benjamin H Chi; Dorothy Mbori-Ngacha; Shaffiq Essajee; Lynne M Mofenson; Fatima Tsiouris; Mary Mahy; Chewe Luo
Journal:  J Int AIDS Soc       Date:  2020-08       Impact factor: 5.396

4.  Factors affecting acceptance of at-birth point of care HIV testing among providers and parents in Kenya: A qualitative study.

Authors:  Catherine Wexler; May Maloba; Melinda Brown; Natabhona Mabachi; Kathy Goggin; Brad Gautney; Beryne Odeny; Sarah Finocchario-Kessler
Journal:  PLoS One       Date:  2019-11-22       Impact factor: 3.240

Review 5.  Point-of-care tests detecting HIV nucleic acids for diagnosis of HIV-1 or HIV-2 infection in infants and children aged 18 months or less.

Authors:  Eleanor A Ochodo; Fatuma Guleid; Jonathan J Deeks; Sue Mallett
Journal:  Cochrane Database Syst Rev       Date:  2021-08-12
  5 in total

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