Literature DB >> 33464012

ART Initiation for Infants Diagnosed With HIV Through Point of Care and Conventional Polymerase Chain Reaction Testing in Kenya: A Case Series.

Catherine Wexler1, May Maloba2, Kathy Goggin3,4, Shadrack Babu Kale5, Nicodemus Maosa5, Elizabeth Muchoki5, Melinda Brown1, Brad Gautney6, Sarah Finocchario-Kessler1.   

Abstract

We sought to understand the sequence of testing and treatment among nine infants offered both conventional and point-of-care testing and diagnosed as HIV-positive by 6 months of age in Kenya. One infant received per protocol testing and treatment. Patient-level (late presentation and disengagement), provider-level (reluctance and error/oversight) and system-level (stock outs, errors) challenges delayed diagnosis and treatment. Early point-of-care testing can streamline testing; however, challenges mitigate benefits.
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Year:  2021        PMID： 33464012      PMCID： PMC7954882          DOI： 10.1097/INF.0000000000003032

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN： 0891-3668            Impact factor:   3.806


  8 in total

1.  Xpert HIV-1 point-of-care test for neonatal diagnosis of HIV in the birth testing programme of a maternity hospital: a field evaluation study.

Authors:  Karl-Günter Technau; Louise Kuhn; Ashraf Coovadia; Pamela M Murnane; Gayle Sherman
Journal:  Lancet HIV       Date:  2017-07-12       Impact factor: 12.767

2.  "Closing the Gap": Provider Recommendations for Implementing Birth Point of Care HIV Testing.

Authors:  Catherine Wexler; Yvonne Kamau; Ritika Halder; Melinda Brown; May Maloba; Natabhona Mabachi; Matthew Sandbulte; Brad Gautney; Kathy Goggin; Thomas Odeny; Sarah Finocchario-Kessler
Journal:  AIDS Behav       Date:  2019-04

3.  Predictors of Early ART Initiation Among HIV + Infants in Kenya: A Retrospective Review of HITSystem Data from 2013 to 2017.

Authors:  Catherine Wexler; Niaman Nazir; Brad Gautney; May Maloba; Melinda Brown; Kathy Goggin; Raphael Lwembe; Sarah Finocchario-Kessler
Journal:  Matern Child Health J       Date:  2020-06

4.  Emergence of a peak in early infant mortality due to HIV/AIDS in South Africa.

Authors:  David E Bourne; MaryLou Thompson; Linnea L Brody; Mark Cotton; Beverly Draper; Ria Laubscher; M Fareed Abdullah; Jonny E Myers
Journal:  AIDS       Date:  2009-01-02       Impact factor: 4.177

5.  Birth diagnosis of HIV infection in infants to reduce infant mortality and monitor for elimination of mother-to-child transmission.

Authors:  Rivka R Lilian; Emma Kalk; Karl-Gunter Technau; Gayle G Sherman
Journal:  Pediatr Infect Dis J       Date:  2013-10       Impact factor: 2.129

6.  Effect of point-of-care early infant diagnosis on antiretroviral therapy initiation and retention of patients.

Authors:  Ilesh V Jani; Bindiya Meggi; Osvaldo Loquiha; Ocean Tobaiwa; Chishamiso Mudenyanga; Alcina Zitha; Dadirayi Mutsaka; Nedio Mabunda; Adolfo Vubil; Timothy Bollinger; Lara Vojnov; Trevor F Peter
Journal:  AIDS       Date:  2018-07-17       Impact factor: 4.177

7.  Significant Patient Impact Observed Upon Implementation of Point-of-Care Early Infant Diagnosis Technologies in an Observational Study in Malawi.

Authors:  Reuben Mwenda; Youyi Fong; Termson Magombo; Emmanuel Saka; Dalitso Midiani; Christopher Mwase; James Kandulu; Melody Wang; Rachel Thomas; Judith Sherman; Lara Vojnov
Journal:  Clin Infect Dis       Date:  2018-08-16       Impact factor: 9.079

8.  Infant HIV testing at birth using point-of-care and conventional HIV DNA PCR: an implementation feasibility pilot study in Kenya.

Authors:  Matthew R Sandbulte; Brad J Gautney; May Maloba; Catherine Wexler; Melinda Brown; Natabhona Mabachi; Kathy Goggin; Raphael Lwembe; Niaman Nazir; Thomas A Odeny; Sarah Finocchario-Kessler
Journal:  Pilot Feasibility Stud       Date:  2019-01-25
  8 in total
  1 in total

1.  Piloting the Feasibility and Preliminary Impact of Adding Birth HIV Polymerase Chain Reaction Testing to the Early Infant Diagnosis Guidelines in Kenya.

Authors:  Sarah Finocchario-Kessler; Catherine Wexler; Melinda Brown; Kathy Goggin; Raphael Lwembe; Niaman Nazir; Brad Gautney; Samoel Khamadi; Shadrack Babu; Elizabeth Muchoki; Nicodemus Maosa; Natabhona Mabachi; Yvonne Kamau; May Maloba
Journal:  Pediatr Infect Dis J       Date:  2021-08-01       Impact factor: 2.129
  1 in total

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