Literature DB >> 3054154

Recombinant retroviruses encoding cell surface antigens as selectable markers.

R K Strair1, M J Towle, B R Smith.   

Abstract

Recombinant retroviruses are frequently used in the transfer and analysis of genes. This report describes new retrovirus vectors that incorporate a cDNA copy of a cell surface antigen to function as a selectable marker. By using techniques based on quantitative cell surface immunofluorescence, these vectors allow the rapid detection and isolation of infected cells. These vectors also allow the rapid detection of packaging cell lines producing large amounts of recombinant retroviruses. Potential applications of these vectors are demonstrated.

Entities:  

Mesh：

Substances：

Year:  1988        PMID： 3054154      PMCID： PMC253592     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  13 in total

1.  Expression of human class II major histocompatibility complex antigens using retrovirus vectors.

Authors:  A J Korman; J D Frantz; J L Strominger; R C Mulligan
Journal:  Proc Natl Acad Sci U S A       Date:  1987-04       Impact factor: 11.205

2.  Regulated expression of a complete human beta-globin gene encoded by a transmissible retrovirus vector.

Authors:  R D Cone; A Weber-Benarous; D Baorto; R C Mulligan
Journal:  Mol Cell Biol       Date:  1987-02       Impact factor: 4.272

3.  Use of recombinant retroviruses to study the regulation of integrated adenovirus early promoters.

Authors:  R K Strair; J S Miller; B E Roberts
Journal:  J Virol       Date:  1988-06       Impact factor: 5.103

4.  Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus.

Authors:  R Mann; R C Mulligan; D Baltimore
Journal:  Cell       Date:  1983-05       Impact factor: 41.582

5.  Construction and applications of a highly transmissible murine retrovirus shuttle vector.

Authors:  C L Cepko; B E Roberts; R C Mulligan
Journal:  Cell       Date:  1984-07       Impact factor: 41.582

6.  Gene transfer, expression, and molecular cloning of the human transferrin receptor gene.

Authors:  L C Kühn; A McClelland; F H Ruddle
Journal:  Cell       Date:  1984-05       Impact factor: 41.582

7.  Efficient retrovirus-mediated transfer and expression of a human adenosine deaminase gene in diploid skin fibroblasts from an adenosine deaminase-deficient human.

Authors:  T D Palmer; R A Hock; W R Osborne; A D Miller
Journal:  Proc Natl Acad Sci U S A       Date:  1987-02       Impact factor: 11.205

8.  Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cells.

Authors:  S F Yu; T von Rüden; P W Kantoff; C Garber; M Seiberg; U Rüther; W F Anderson; E F Wagner; E Gilboa
Journal:  Proc Natl Acad Sci U S A       Date:  1986-05       Impact factor: 11.205

9.  Retrovirus-mediated transfer and expression of drug resistance genes in human haematopoietic progenitor cells.

Authors:  R A Hock; A D Miller
Journal:  Nature       Date:  1986 Mar 20-26       Impact factor: 49.962

10.  Phenotype of recovering lymphoid cell populations after marrow transplantation.

Authors:  K A Ault; J H Antin; D Ginsburg; S H Orkin; J M Rappeport; M L Keohan; P Martin; B R Smith
Journal:  J Exp Med       Date:  1985-06-01       Impact factor: 14.307
View more
  5 in total

1.  Retroviral mediated gene transfer into bone marrow progenitor cells: use of beta-galactosidase as a selectable marker.

Authors:  R K Strair; M Towle; B R Smith
Journal:  Nucleic Acids Res       Date:  1990-08-25       Impact factor: 16.971

Review 2.  Towards in vivo amplification: Overcoming hurdles in the use of hematopoietic stem cells in transplantation and gene therapy.

Authors:  Murtaza S Nagree; Lucía López-Vásquez; Jeffrey A Medin
Journal:  World J Stem Cells       Date:  2015-12-26       Impact factor: 5.326

3.  Rapid titration of retroviral vectors encoding intracellular antigens by flow cytometry.

Authors:  T L Sladek; J W Jacobberger
Journal:  J Virol       Date:  1990-06       Impact factor: 5.103

4.  Screening retroviral packaging cells for highly efficient virus production by using a combined selection procedure.

Authors:  M Wirth; R Grannemann; D Klehr; H Hauser
Journal:  J Virol       Date:  1994-01       Impact factor: 5.103

5.  Selection of transduced CD34+ progenitors and enzymatic correction of cells from Gaucher patients, with bicistronic vectors.

Authors:  M Migita; J A Medin; R Pawliuk; S Jacobson; J W Nagle; S Anderson; M Amiri; R K Humphries; S Karlsson
Journal:  Proc Natl Acad Sci U S A       Date:  1995-12-19       Impact factor: 11.205
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.