| Literature DB >> 30532135 |
Jinjing Wu1,2, Shelby Deaton2, Boshen Jiao2,3, Zohn Rosen2, Peter A Muennig4.
Abstract
OBJECTIVE: The New Rural Cooperative Medical Scheme (NCMS) is a universal healthcare coverage plan now covering over 98% of rural residents in China, first implemented in 2003. Rising costs in the face of modest gains in health and financial protections have raised questions about the cost-effectiveness of the NCMS.Entities:
Mesh:
Year: 2018 PMID: 30532135 PMCID: PMC6287900 DOI: 10.1371/journal.pone.0208297
Source DB: PubMed Journal: PLoS One ISSN: 1932-6203 Impact factor: 3.240
Model inputs used in the analysis comparing NCMS and no NCMS * (NCMS = New Rural Cooperative Medical Scheme).
| Parameters | Base | Low | High | Source |
|---|---|---|---|---|
| Marginal Effects of NCSM on age-standardized mortality rate per 1,000 population | ||||
| Male, aged 20–44 years | -0.10 | -0.28 | 0.08 | Zhou et al., 2017 |
| Male, aged 45–59 years | -0.14 | -0.57 | 0.29 | |
| Male, aged 60 and above | 0.36 | -3.01 | 3.73 | |
| Female, aged 20–44 years | -0.05 | -0.12 | 0.03 | |
| Female, aged 45–59 years | -0.05 | -0.32 | 0.23 | |
| Female, aged 60 and above | 1.05 | -1.72 | 3.82 | |
| Risk ratio of being hypertensive for the NCMS group | 0.98 | 0.95 | 1.00 | Cheng et al., 2015 |
| Probability of off-farm labor participation | 0.17 | Shen et al., 2017 | ||
| Increase in probability of off-farm labor participation | ||||
| Aged 30–49 years | 0.13 | 0.07 | 0.20 | Shen et al., 2017 |
| Aged 50 years or more | 0.07 | 0.03 | 0.11 | |
| Health expense growth rate | 0.61 | 0.50 | 0.70 | Wagstaff et al., 2009 |
| Annual discount rate for economic costs, benefits, and quality-adjusted life-years | 0.03 | 0.00 | 0.05 | Weinstein et al., 1996 |
| Increase in probability of off-farm labor participation | ||||
| Aged 30–49 years | 0.13 | 0.07 | 0.20 | Shen et al., 2017 |
| Normotensives | 0.98 | 0.98 | 0.98 | Zhang et al., 2017 |
| Hypertensives | 0.92 | 0.90 | 0.94 | |
| Total health expenditure per rural resident | 359 | 243 | 977 | CMOH, 2014 |
| Hypertension-related medical costs per year | 392 | 344 | 441 | Liang et al., 2011 |
| Annual wage per rural resident | 1029 | 350 | 4198 | NBS, 2015 |
| Income per hour in agriculture | 1.44 | 0.47 | 2.59 | NBS, 2015 & Shen et al., 2017 |
| Increase in hours of working in agriculture per year | ||||
| Aged 30–49 years | 1.10 | 0.84 | 1.44 | Shen et al., 2017 |
| Aged 50 years and above | 1.28 | 1.07 | 1.53 |
* The baseline values are the most likely. We used the high and low values in one-way sensitivity analyses and a Monte Carlo simulation.
† Estimated by Zhou and their colleagues [21].
‡ The baseline value was based on a quasi-experimental study done by Wagstaff and his colleagues [14]. The high and low values were bounded by the team consensus as to the most plausible values.
§ 1 international dollar = 3.55 CNY.
|| We obtained the data of annual wage per rural resident from the 2015 China Rural Statistical Yearbook [35].
Assumptions used in the Markov model evaluating the implementation of NCMS versus no NCMS in China.
| 1. The health-related quality of life (HRQL) scores among hypertensive and normotensive individuals were based on an observational study in Shandong Province, China [ |
| 2. The risk ratio of having measured hypertension in the NCMS group was based on a natural experimental study, with data from a nationally representative sample of people aged 60 years or above [ |
| 3. We assumed that once simulated participants get hypertension, they would remain hypertensive, and would be subject to a decrease in the HRQL score and incur hypertension-related medical expenses for the rest of their life. |
| 4. We assumed that having hypertension did not increase the risk of mortality in the hypothetical cohort. |
The base-case cost-effectiveness analysis of the NCMS versus no NCMS (NCMS = New Rural Cooperative Medical Scheme).
| Cost, Int$ | Incremental cost, Int$ | Effectiveness, QALYs | Incremental effectiveness, QALYs | ICER, Int$ | |
|---|---|---|---|---|---|
| No NCMS | 1,010 | 14.21 | |||
| NCMS | 1,836 | 825 | 14.22 | 0.01 | 71,480 |
* Int$ = international dollars. 1 International dollar = 3.55 CNY.
† QALY = quality-adjusted life year.
Fig 1The scatterplot of incremental cost-effectiveness ratio comparing the NCMS to no NCMS (NCMS = New Rural Cooperative Medical System).
The willingness-to-pay (WTP) threshold is three times per capita GDP (Int$37,059 after the purchasing power parity adjustment. 1 international dollar = 3.55 CNY).
One-way sensitivity analyses of the NCMS versus no NCMS (NCMS = New Rural Cooperative Medical Scheme).
| Parameters | Incremental cost, Int$ | Incremental effectiveness, QALYs | Effect on ICER, Int$ | |||
|---|---|---|---|---|---|---|
| Low | High | Low | High | Low | High | |
| Marginal Effects of NCSM on Mortality, Males 20–44 | 909 | 910 | 0.04 | -0.01 | 25,300 | Dominated |
| Marginal Effects of NCSM on Mortality, Males 45–59 | 910 | 908 | 0.03 | -0.001 | 36,207 | Dominated |
| Marginal Effects of NCSM on Mortality, Males 60+ | 915 | 903 | 0.05 | -0.03 | 17,192 | Dominated |
| Marginal Effects of NCSM on Mortality, Females 20–44 | 909 | 909 | 0.02 | 0.002 | 41,534 | 382,543 |
| Marginal Effects of NCSM on Mortality, Females 45–59 | 910 | 908 | 0.02 | 0.004 | 44,035 | 251,646 |
| Marginal Effects of NCSM on Mortality, Females 60+ | 915 | 904 | 0.05 | -0.02 | 18,121 | Dominated |
| Risk ratio of having hypertension for the NCMS group | 863 | 950 | 0.02 | 0.01 | 45,728 | 157,694 |
| Total health expenditure per rural resident | -911 | 3805 | 0.01 | 0.01 | Cost-saving | 313,855 |
| Growth rate in the total health expenditure per rural resident | 523 | 1,228 | 0.01 | 0.01 | 43,141 | 101,285 |
| Increase in the probability of off-farm labor participation | ||||||
| Aged 30–49 years | 1749 | 43 | 0.01 | 0.01 | 144,289 | 3,532 |
| Aged 50–59 years | 1276 | 524 | 0.01 | 0.01 | 105,247 | 43,188 |
| Annual wage per rural resident | 2865 | -2122 | 0.01 | 0.01 | 236,304 | Cost-saving |
| Discount Rate | 2540 | 478 | -0.01 | 0.01 | Dominated | 68,012 |
* Int$ = international dollars. 1 International dollar = 3.55 CNY.
† QALY = quality-adjusted life year.