| Literature DB >> 30517623 |
Yoriko Heianza1, Lu Qi1,2.
Abstract
Obesity and abdominal obesity have been closely related to cardiovascular outcomes, and recent evidence has indicated that environmental and genetic factors act in concert in determining the risks of these conditions. Improving adherence to healthy lifestyle habits and healthy dietary patterns can at least partly counteract genetic variations related to risks of obesity and cardiovascular disease (CVD). Other factors, such as epigenetic alterations, may also modulate a relationship between genetic susceptibility and these disorders. In this review, we highlight data from recent studies on gene and environmental risk factors for obesity and CVD, and describe how these findings might inform understanding of the complex roles of interactions between genes and environmental factors in the development of obesity and CVD.Entities:
Mesh:
Year: 2019 PMID: 30517623 PMCID: PMC6304107 DOI: 10.1210/en.2018-00591
Source DB: PubMed Journal: Endocrinology ISSN: 0013-7227 Impact factor: 4.736