Literature DB >> 30513005

Challenges with risk mitigation in academic drug discovery: finding the best solution.

Anuradha Roy1.   

Abstract

Entities:  

Keywords:  Probe discovery; academia-pharma; drug discovery; high throughput screening

Mesh：

Year:  2018        PMID： 30513005      PMCID： PMC6467222          DOI： 10.1080/17460441.2019.1553952

Source DB:  PubMed          Journal:  Expert Opin Drug Discov        ISSN： 1746-0441            Impact factor:   6.098


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  15 in total

1.  NIH Molecular Libraries Initiative.

Authors:  Christopher P Austin; Linda S Brady; Thomas R Insel; Francis S Collins
Journal:  Science       Date:  2004-11-12       Impact factor: 47.728

2.  Tackling reproducibility in academic preclinical drug discovery.

Authors:  Stephen V Frye; Michelle R Arkin; Cheryl H Arrowsmith; P Jeffrey Conn; Marcie A Glicksman; Emily A Hull-Ryde; Barbara S Slusher
Journal:  Nat Rev Drug Discov       Date:  2015-09-21       Impact factor: 84.694

3.  Bringing together the academic drug discovery community.

Authors:  Barbara S Slusher; P Jeffrey Conn; Stephen Frye; Marcie Glicksman; Michelle Arkin
Journal:  Nat Rev Drug Discov       Date:  2013-11       Impact factor: 84.694

Review 4.  Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes.

Authors:  Stuart L Schreiber; Joanne D Kotz; Min Li; Jeffrey Aubé; Christopher P Austin; John C Reed; Hugh Rosen; E Lucile White; Larry A Sklar; Craig W Lindsley; Benjamin R Alexander; Joshua A Bittker; Paul A Clemons; Andrea de Souza; Michael A Foley; Michelle Palmer; Alykhan F Shamji; Mathias J Wawer; Owen McManus; Meng Wu; Beiyan Zou; Haibo Yu; Jennifer E Golden; Frank J Schoenen; Anton Simeonov; Ajit Jadhav; Michael R Jackson; Anthony B Pinkerton; Thomas D Y Chung; Patrick R Griffin; Benjamin F Cravatt; Peter S Hodder; William R Roush; Edward Roberts; Dong-Hoon Chung; Colleen B Jonsson; James W Noah; William E Severson; Subramaniam Ananthan; Bruce Edwards; Tudor I Oprea; P Jeffrey Conn; Corey R Hopkins; Michael R Wood; Shaun R Stauffer; Kyle A Emmitte
Journal:  Cell       Date:  2015-06-04       Impact factor: 41.582

5.  Drug discoverers chart path to tackling data irreproducibility.

Authors:  Elie Dolgin
Journal:  Nat Rev Drug Discov       Date:  2014-12       Impact factor: 84.694

6.  Academia-pharma partnerships for novel drug discovery: essential or nice to have?

Authors:  Michelle Palmer; Rathnam Chaguturu
Journal:  Expert Opin Drug Discov       Date:  2017-04-17       Impact factor: 6.098

Review 7.  Probing the probes: fitness factors for small molecule tools.

Authors:  Paul Workman; Ian Collins
Journal:  Chem Biol       Date:  2010-06-25

Review 8.  Contributions of academic laboratories to the discovery and development of chemical biology tools.

Authors:  Donna M Huryn; Lynn O Resnick; Peter Wipf
Journal:  J Med Chem       Date:  2013-05-31       Impact factor: 7.446

Review 9.  Target validation: linking target and chemical properties to desired product profile.

Authors:  Paul G Wyatt; Ian H Gilbert; Kevin D Read; Alan H Fairlamb
Journal:  Curr Top Med Chem       Date:  2011       Impact factor: 3.295

10.  A cell-based high-throughput screen for novel chemical inducers of fetal hemoglobin for treatment of hemoglobinopathies.

Authors:  Kenneth R Peterson; Flávia C Costa; Halyna Fedosyuk; Renee Y Neades; Allen M Chazelle; Lesya Zelenchuk; Andrea H Fonteles; Parmita Dalal; Anuradha Roy; Rathnam Chaguturu; Biaoru Li; Betty S Pace
Journal:  PLoS One       Date:  2014-09-16       Impact factor: 3.240
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  2 in total

Review 1.  Resources and computational strategies to advance small molecule SARS-CoV-2 discovery: lessons from the pandemic and preparing for future health crises.

Authors:  Natesh Singh; Bruno O Villoutreix
Journal:  Comput Struct Biotechnol J       Date:  2021-04-26       Impact factor: 7.271

2.  RNA-PROTACs: Degraders of RNA-Binding Proteins.

Authors:  Alice Ghidini; Antoine Cléry; François Halloy; Frédéric H T Allain; Jonathan Hall
Journal:  Angew Chem Int Ed Engl       Date:  2020-12-10       Impact factor: 15.336
  2 in total

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