Literature DB >> 30450526

Experimental Study of the Effectiveness of Phenolic Antioxidants in Male Infertility Caused by Pathospermia.

T G Borovskaya1, S I Kamalova2, N A Krivova3, O B Zaeva3, M E Poluektova2, A V Vychuzhanina2, V A Grigor'eva2, M B Plotnikov2, V E Goldberg4.   

Abstract

The effect of phenolic antioxidants (dihydroquercetin, p-tyrosol, dibornol) on the morphology, functions, and redox processes in the reproductive cells of male rats was studied on the model of experimental pathospermia. All antioxidants reduced the percentage of degenerative forms of spermatozoa. Dibornol was most effective. Dihydroquercetin and p-tyrosol did not increase the total number of spermatozoa and the percentage of their mobile forms. These indicators were improved only by dibornol. After administration of all test drugs, the antioxidant potential of spermatozoa increased and did not significantly differ from the baseline values.

Entities:  

Keywords:  male infertility; oxidative stress; pathospermia; phenolic antioxidants

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Year:  2018        PMID： 30450526     DOI： 10.1007/s10517-018-4276-6

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN： 0007-4888            Impact factor:   0.804


  2 in total

1.  Estimation of the Regenerative Potential of para-Tyrosol in the Model of Testicular Insufficiency Caused by Damage to Spermatogonial Stem Cells.

Authors:  T G Borovskaya; V A Grigor'eva; Yu A Shchemerova; S I Kamalova; A V Vychuzhanina; N A Krivova; O B Zaeva; V E Goldberg; A M Dygai
Journal:  Bull Exp Biol Med       Date:  2022-03-30       Impact factor: 0.804

2.  Delayed Consequences of the Toxic Effect of Paclitaxel on the Testes of Prepubertal Rats and Their Correction with p-Tyrosol.

Authors:  T G Borovskaya; V A Grigor'eva; Yu A Shchemerova; E A Bokhan; A V Vychuzhanina; S I Kamalova; V E Goldberg
Journal:  Bull Exp Biol Med       Date:  2022-07-19       Impact factor: 0.737
  2 in total

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