R Figueroa1, A Alfonso1, J López-Picazo2, I Gil-Bazo2, A García-Mouriz3, J Hermida4,5, J A Páramo1,5, R Lecumberri6,7. 1. Hematology Service, University Clinic of Navarra, Av. Pío XII 36, 31008, Pamplona, Spain. 2. Oncology Department, University Clinic of Navarra, Pamplona, Spain. 3. Informatics Service, University Clinic of Navarra, Pamplona, Spain. 4. Center for Applied Medical Research, University of Navarra, Pamplona, Spain. 5. Centro de Investigación Biomédica en Red (CIBER-CV), Instituto de Salud Carlos III, Madrid, Spain. 6. Hematology Service, University Clinic of Navarra, Av. Pío XII 36, 31008, Pamplona, Spain. rlecumber@unav.es. 7. Centro de Investigación Biomédica en Red (CIBER-CV), Instituto de Salud Carlos III, Madrid, Spain. rlecumber@unav.es.
Abstract
PURPOSE: Thromboprophylaxis use among medical inpatients, including cancer patients, is suboptimal. We aimed to evaluate the impact of a novel multiscreen version (v2.0) of an e-alert system for VTE prevention in hospitalised cancer medical patients compared to the original software. METHODS: Prospective study including 989 consecutive adult cancer patients with high-risk of VTE. Patients were followed-up 30 days post-discharge. Two periods were defined, according to the operative software. RESULTS: E-alert v2.0 was associated with an increase in the use of LMWH prophylaxis (65.5% vs. 72.0%); risk difference (95% CI) 0.064 (0.0043-0.12). Only 16% of patients in whom LMWH prophylaxis was not prescribed lacked a contraindication. No significant differences in the rates of VTE (2.9% vs. 3.2%) and major bleeding (2.7% vs. 4.0%) were observed. CONCLUSIONS: E-alert v2.0 further increased the use of appropriate thromboprophylaxis in hospitalised cancer patients, although was not associated with a reduction in VTE incidence.
PURPOSE: Thromboprophylaxis use among medical inpatients, including cancerpatients, is suboptimal. We aimed to evaluate the impact of a novel multiscreen version (v2.0) of an e-alert system for VTE prevention in hospitalised cancer medical patients compared to the original software. METHODS: Prospective study including 989 consecutive adult cancerpatients with high-risk of VTE. Patients were followed-up 30 days post-discharge. Two periods were defined, according to the operative software. RESULTS: E-alert v2.0 was associated with an increase in the use of LMWH prophylaxis (65.5% vs. 72.0%); risk difference (95% CI) 0.064 (0.0043-0.12). Only 16% of patients in whom LMWH prophylaxis was not prescribed lacked a contraindication. No significant differences in the rates of VTE (2.9% vs. 3.2%) and major bleeding (2.7% vs. 4.0%) were observed. CONCLUSIONS: E-alert v2.0 further increased the use of appropriate thromboprophylaxis in hospitalised cancerpatients, although was not associated with a reduction in VTE incidence.
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