Literature DB >> 3043188

B-raf, a new member of the raf family, is activated by DNA rearrangement.

S Ikawa1, M Fukui, Y Ueyama, N Tamaoki, T Yamamoto, K Toyoshima.   

Abstract

Complementary DNA clones of a putative transforming gene were isolated from NIH 3T3 cells transformed with human Ewing sarcoma DNA. The gene was termed B-raf because it is related to but distinct from c-raf and A-raf. It appears that substitution in the amino-terminal portion of the normal B-raf protein confers transforming activity to the gene.

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Year:  1988        PMID： 3043188      PMCID： PMC363468          DOI： 10.1128/mcb.8.6.2651-2654.1988

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  29 in total

1.  A general method for isolation of high molecular weight DNA from eukaryotes.

Authors:  N Blin; D W Stafford
Journal:  Nucleic Acids Res       Date:  1976-09       Impact factor: 16.971

2.  Rapid and efficient cosmid cloning.

Authors:  D Ish-Horowicz; J F Burke
Journal:  Nucleic Acids Res       Date:  1981-07-10       Impact factor: 16.971

3.  A small cosmid for efficient cloning of large DNA fragments.

Authors:  B Hohn; J Collins
Journal:  Gene       Date:  1980-11       Impact factor: 3.688

4.  The isolation of structural genes from libraries of eucaryotic DNA.

Authors:  T Maniatis; R C Hardison; E Lacy; J Lauer; C O'Connell; D Quon; G K Sim; A Efstratiadis
Journal:  Cell       Date:  1978-10       Impact factor: 41.582

5.  Plasmid screening at high colony density.

Authors:  D Hanahan; M Meselson
Journal:  Gene       Date:  1980-06       Impact factor: 3.688

6.  Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose.

Authors:  H Aviv; P Leder
Journal:  Proc Natl Acad Sci U S A       Date:  1972-06       Impact factor: 11.205

7.  Human DNA sequence homologous to the transforming gene (mos) of Moloney murine sarcoma virus.

Authors:  R Watson; M Oskarsson; G F Vande Woude
Journal:  Proc Natl Acad Sci U S A       Date:  1982-07       Impact factor: 11.205

8.  Ubiquitous, interspersed repeated sequences in mammalian genomes.

Authors:  W R Jelinek; T P Toomey; L Leinwand; C H Duncan; P A Biro; P V Choudary; S M Weissman; C M Rubin; C M Houck; P L Deininger; C W Schmid
Journal:  Proc Natl Acad Sci U S A       Date:  1980-03       Impact factor: 11.205

9.  Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus.

Authors:  U R Rapp; M D Goldsborough; G E Mark; T I Bonner; J Groffen; F H Reynolds; J R Stephenson
Journal:  Proc Natl Acad Sci U S A       Date:  1983-07       Impact factor: 11.205

10.  Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease.

Authors:  J M Chirgwin; A E Przybyla; R J MacDonald; W J Rutter
Journal:  Biochemistry       Date:  1979-11-27       Impact factor: 3.162
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  55 in total

1.  High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1.

Authors:  A Sewing; B Wiseman; A C Lloyd; H Land
Journal:  Mol Cell Biol       Date:  1997-09       Impact factor: 4.272

2.  95-kilodalton B-Raf serine/threonine kinase: identification of the protein and its major autophosphorylation site.

Authors:  R M Stephens; G Sithanandam; T D Copeland; D R Kaplan; U R Rapp; D K Morrison
Journal:  Mol Cell Biol       Date:  1992-09       Impact factor: 4.272

Review 3.  A brief history of melanoma: from mummies to mutations.

Authors:  Vito W Rebecca; Vernon K Sondak; Keiran S M Smalley
Journal:  Melanoma Res       Date:  2012-04       Impact factor: 3.599

Review 4.  Mechanistic principles of RAF kinase signaling.

Authors:  Christian M Udell; Thanashan Rajakulendran; Frank Sicheri; Marc Therrien
Journal:  Cell Mol Life Sci       Date:  2010-09-06       Impact factor: 9.261

5.  Development of a highly efficient expression cDNA cloning system: application to oncogene isolation.

Authors:  T Miki; T P Fleming; M Crescenzi; C J Molloy; S B Blam; S H Reynolds; S A Aaronson
Journal:  Proc Natl Acad Sci U S A       Date:  1991-06-15       Impact factor: 11.205

6.  Molecular organization of the human Raf-1 promoter region.

Authors:  T W Beck; U Brennscheidt; G Sithanandam; J Cleveland; U R Rapp
Journal:  Mol Cell Biol       Date:  1990-07       Impact factor: 4.272

7.  Common mechanism of retrovirus activation and transduction of c-mil and c-Rmil in chicken neuroretina cells infected with Rous-associated virus type 1.

Authors:  M P Felder; A Eychène; J V Barnier; I Calogeraki; G Calothy; M Marx
Journal:  J Virol       Date:  1991-07       Impact factor: 5.103

8.  Inhibition of platelet-derived growth factor- and epidermal growth factor-mediated mitogenesis and signaling in 3T3 cells expressing delta Raf-1:ER, an estradiol-regulated form of Raf-1.

Authors:  M L Samuels; M McMahon
Journal:  Mol Cell Biol       Date:  1994-12       Impact factor: 4.272

9.  Differential regulation of B-raf isoforms by phosphorylation and autoinhibitory mechanisms.

Authors:  Isabelle Hmitou; Sabine Druillennec; Agathe Valluet; Carole Peyssonnaux; Alain Eychène
Journal:  Mol Cell Biol       Date:  2006-10-30       Impact factor: 4.272

Review 10.  Vemurafenib: the first drug approved for BRAF-mutant cancer.

Authors:  Gideon Bollag; James Tsai; Jiazhong Zhang; Chao Zhang; Prabha Ibrahim; Keith Nolop; Peter Hirth
Journal:  Nat Rev Drug Discov       Date:  2012-10-12       Impact factor: 84.694
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