| Literature DB >> 3041048 |
J G Spivack, D R O'Boyle, N W Fraser.
Abstract
Herpes simplex virus type 1 was reactivated from the trigeminal ganglia of latently infected mice in a quantitative and time-dependent manner. Novobiocin and coumermycin A1 reversibly inhibited the reactivation of herpes simplex virus type 1. They did not inhibit viral replication in permissive cells (CV-1) but did inhibit replication in cells of neuronal origin (C1300) and acutely infected trigeminal ganglia.Entities:
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Year: 1987 PMID: 3041048 PMCID: PMC255910 DOI: 10.1128/JVI.61.10.3288-3291.1987
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103