Literature DB >> 30398488

Light-enhanced hypoxia-responsive nanoparticles for deep tumor penetration and combined chemo-photodynamic therapy.

Zhongbao Li1, Min Wu, Hongzhen Bai, Xingang Liu, Guping Tang.   

Abstract

Herein, we report a light-enhanced hypoxia-responsive nanoparticle for synergic treatment of solid tumors. The conversion of oxygen in the tumor exterior induced ROS and the continuous consumption of oxygen amplified the hypoxia conditions in the tumor, which enhanced the surface-to-core penetration of nanoparticles into the hypoxia central tissue.

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Year:  2018        PMID： 30398488     DOI： 10.1039/c8cc08445a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  6 in total

Review 1.  Fighting Hypoxia to Improve PDT.

Authors:  Ludivine Larue; Bauyrzhan Myrzakhmetov; Amina Ben-Mihoub; Albert Moussaron; Noémie Thomas; Philippe Arnoux; Francis Baros; Régis Vanderesse; Samir Acherar; Céline Frochot
Journal:  Pharmaceuticals (Basel)       Date:  2019-10-30

2.  Clinical significance of high expression of stanniocalcin-2 in hepatocellular carcinoma.

Authors:  Yuan Wang; Jian Wu; Jiangyan Xu; Shengyou Lin
Journal:  Biosci Rep       Date:  2019-04-26       Impact factor: 3.840

Review 3.  Tumor Microenvironment-Stimuli Responsive Nanoparticles for Anticancer Therapy.

Authors:  Reju George Thomas; Suchithra Poilil Surendran; Yong Yeon Jeong
Journal:  Front Mol Biosci       Date:  2020-12-18

Review 4.  Applications of Surface Modification Technologies in Nanomedicine for Deep Tumor Penetration.

Authors:  Zimu Li; Xiaoting Shan; Zhidong Chen; Nansha Gao; Wenfeng Zeng; Xiaowei Zeng; Lin Mei
Journal:  Adv Sci (Weinh)       Date:  2020-11-27       Impact factor: 16.806

Review 5.  Enhancing the therapeutic efficacy of nanoparticles for cancer treatment using versatile targeted strategies.

Authors:  Hailong Tian; Tingting Zhang; Siyuan Qin; Zhao Huang; Li Zhou; Jiayan Shi; Edouard C Nice; Na Xie; Canhua Huang; Zhisen Shen
Journal:  J Hematol Oncol       Date:  2022-09-12       Impact factor: 23.168

6.  Hypoxia-responsive nanoreactors based on self-enhanced photodynamic sensitization and triggered ferroptosis for cancer synergistic therapy.

Authors:  Xiaoyan Wang; Ming Wu; Xiaolong Zhang; Feida Li; Yongyi Zeng; Xinyi Lin; Xiaolong Liu; Jingfeng Liu
Journal:  J Nanobiotechnology       Date:  2021-07-08       Impact factor: 10.435
  6 in total

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