Myeongsook Seo1, Segyeong Joo2, Kee Wook Jung3, Eun Mi Song4, Satish S C Rao5, Seung-Jae Myung6. 1. Department of Internal Medicine, Konkuk University Chungju Hospital, Chungju, South Korea. 2. Department of Biomedical Engineering, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea. 3. Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea. jung.keewook@amc.seoul.kr. 4. Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea. 5. Division of Gastroenterology and Hepatology, Department of Medicine, Augusta University, Augusta, GA, USA. 6. Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea. sjmyung@amc.seoul.kr.
Abstract
PURPOSE OF REVIEW: To review recently published diagnostic methods that use high-resolution (HR-) or high-definition- (HD-) anorectal manometry (ARM) techniques. RECENT FINDINGS: The integrated pressurized volume (IPV) is a new measure based on spatiotemporal plots obtained from HR-ARM. The IPV may be clinically useful for improving the prediction of abnormal balloon expulsion test in patients with constipation and for discriminating patients with anorectal disorders from asymptomatic controls. Combination of IPV parameters was superior to conventional manometric parameters in predicting the responsiveness to biofeedback therapy. Moreover, several novel parameters including the HR-ARM resting integral, HR-ARM squeeze profile, and anorectal asymmetry index may each be useful as predictive factors for identifying patients with fecal incontinence. HR- and HD-ARM are increasingly performed worldwide for evaluation of anorectal function. Here, we describe new metrics whose clinical significance has not been fully established. Further standardization and validation of these metrics could provide clinically important new information and could help improve our understanding of the pathophysiology of anorectal disorders.
PURPOSE OF REVIEW: To review recently published diagnostic methods that use high-resolution (HR-) or high-definition- (HD-) anorectal manometry (ARM) techniques. RECENT FINDINGS: The integrated pressurized volume (IPV) is a new measure based on spatiotemporal plots obtained from HR-ARM. The IPV may be clinically useful for improving the prediction of abnormal balloon expulsion test in patients with constipation and for discriminating patients with anorectal disorders from asymptomatic controls. Combination of IPV parameters was superior to conventional manometric parameters in predicting the responsiveness to biofeedback therapy. Moreover, several novel parameters including the HR-ARM resting integral, HR-ARM squeeze profile, and anorectal asymmetry index may each be useful as predictive factors for identifying patients with fecal incontinence. HR- and HD-ARM are increasingly performed worldwide for evaluation of anorectal function. Here, we describe new metrics whose clinical significance has not been fully established. Further standardization and validation of these metrics could provide clinically important new information and could help improve our understanding of the pathophysiology of anorectal disorders.
Authors: Gregory Cheeney; Jose M Remes-Troche; Ashok Attaluri; Satish S C Rao Journal: Am J Physiol Gastrointest Liver Physiol Date: 2010-11-25 Impact factor: 4.052
Authors: Shiva K Ratuapli; Adil E Bharucha; Jessica Noelting; Doris M Harvey; Alan R Zinsmeister Journal: Gastroenterology Date: 2012-11-07 Impact factor: 22.682
Authors: Adil E Bharucha; Andrew J Croak; John B Gebhart; Lawrence J Berglund; Barbara M Seide; Alan R Zinsmeister; Kai-Nan An Journal: Am J Physiol Gastrointest Liver Physiol Date: 2006-02-02 Impact factor: 4.052
Authors: P T Heitmann; P Rabbitt; A Schloithe; V Patton; P P Skuza; D A Wattchow; P G Dinning Journal: Int J Colorectal Dis Date: 2019-07-06 Impact factor: 2.571
Authors: Emma V Carrington; Henriette Heinrich; Charles H Knowles; Mark Fox; Satish Rao; Donato F Altomare; Adil E Bharucha; Rebecca Burgell; William D Chey; Guiseppe Chiarioni; Philip Dinning; Anton Emmanuel; Ridzuan Farouk; Richelle J F Felt-Bersma; Kee Wook Jung; Anthony Lembo; Allison Malcolm; Ravinder K Mittal; Franҫois Mion; Seung-Jae Myung; P Ronan O'Connell; Christian Pehl; Jose María Remes-Troche; R Matthew Reveille; Carolynne J Vaizey; Veronique Vitton; William E Whitehead; Reuben K Wong; S Mark Scott Journal: Neurogastroenterol Motil Date: 2019-08-12 Impact factor: 3.598