Literature DB >> 3038515

Localization of the mcf.2 transforming sequence to the X chromosome.

T Noguchi, M G Mattei, I Oberlè, J Planche, J Imbert, C Pelassy, F Birg, D Birnbaum.   

Abstract

A transforming sequence was identified using co-transfection of DNA from the human mammary carcinoma cell line MCF-7 and of a G418 resistance gene into NIH 3T3 cells, followed by tumor formation in athymic mice. This sequence, named mcf.2, was molecularly cloned. A transforming activity resides in a cosmid clone of 42 kb. mcf.2 did not cross-hybridize with the known oncogenes tested. In situ hybridization localized it on the X chromosome, probably at q27. This localization was confirmed by hybridization to a panel of human--rodent cell line DNAs.

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Year:  1987        PMID： 3038515      PMCID： PMC553933          DOI： 10.1002/j.1460-2075.1987.tb02368.x

Source DB:  PubMed          Journal:  EMBO J        ISSN： 0261-4189            Impact factor:   11.598


  33 in total

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Authors:  P S Thomas
Journal:  Proc Natl Acad Sci U S A       Date:  1980-09       Impact factor: 11.205

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Authors:  G R Sutherland; P L Ashforth
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5.  Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter.

Authors:  D A Melton; P A Krieg; M R Rebagliati; T Maniatis; K Zinn; M R Green
Journal:  Nucleic Acids Res       Date:  1984-09-25       Impact factor: 16.971

6.  A small cosmid for efficient cloning of large DNA fragments.

Authors:  B Hohn; J Collins
Journal:  Gene       Date:  1980-11       Impact factor: 3.688

7.  Mechanism of activation of a human oncogene.

Authors:  C J Tabin; S M Bradley; C I Bargmann; R A Weinberg; A G Papageorge; E M Scolnick; R Dhar; D R Lowy; E H Chang
Journal:  Nature       Date:  1982-11-11       Impact factor: 49.962

8.  Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose.

Authors:  H Aviv; P Leder
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9.  Human pancreatic carcinoma (MIA PaCa-2) in continuous culture: sensitivity to asparaginase.

Authors:  A A Yunis; G K Arimura; D J Russin
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10.  Identification of a phosphoprotein specifically induced by the transforming DNA of rat neuroblastomas.

Authors:  L C Padhy; C Shih; D Cowing; R Finkelstein; R A Weinberg
Journal:  Cell       Date:  1982-04       Impact factor: 41.582
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  8 in total

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Authors:  M Schmidt; D Du Sart; P Kalitsis; M Leversha; S Dale; L Sheffield; D Toniolo
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4.  Molecular studies of haemophilia B in Sweden. Identification of patients with total deletion of the factor IX gene and without inhibitory antibodies.

Authors:  C Wadelius; M Blombäck; U Pettersson
Journal:  Hum Genet       Date:  1988-12       Impact factor: 4.132

5.  pmcf.2-11, a single copy clone from chromosomal region 12q12-q13.1 [D12S32].

Authors:  J Oberle; M G Mattei; T Noguchi; D Birnbaum
Journal:  Nucleic Acids Res       Date:  1988-09-12       Impact factor: 16.971

6.  Mutational analysis of proto-oncogene Dbl on Xq27 in testicular germ cell tumors reveals a rare SNP in a patient with bilateral undescended testis.

Authors:  Wan-Hai Xu; Cheng Zhang; Wei-Ming Zhao; Chun-Mei Li; You-Cheng Xiu; Shao-Bin Ni; Ming-Hua Ren; Dian-Jun Sun
Journal:  World J Urol       Date:  2009-12       Impact factor: 4.226

7.  Large scale physical mapping in the q27 region of the human X chromosome: the coagulation factor IX gene and the mcf.2 transforming sequence are separated by at most 270 kilobase pairs and are surrounded by several 'HTF islands'.

Authors:  C Nguyen; P Pontarotti; D Birnbaum; G Chimini; J A Rey; J F Mattei; B R Jordan
Journal:  EMBO J       Date:  1987-11       Impact factor: 11.598

8.  Nullisomic deletion of the mcf.2 transforming gene in two haemophilia B patients.

Authors:  D S Anson; D J Blake; P R Winship; D Birnbaum; G G Brownlee
Journal:  EMBO J       Date:  1988-09       Impact factor: 11.598
  8 in total

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