Literature DB >> 3033606

The action of a water-soluble carbodiimide on adenosine-5'-polyphosphates.

K E Ng, L E Orgel.   

Abstract

When aqueous solutions of adenosine-5'-mono-, di-, or triphosphates are treated with a water soluble carbodiimide the major product is the expected diadenosine-5'-5'-polyphosphate. The yields of these pyrophosphates are greatly increased in the presence of the Mg2+ ion. Adenosine-5'-tetraphosphate behaves differently. The major product is adenosine-5'-monophosphate. We believe that this hydrolysis occurs via a cyclic trimetaphosphate intermediate.

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Year:  1987        PMID： 3033606      PMCID： PMC340750          DOI： 10.1093/nar/15.8.3573

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  8 in total

1.  DISMUTATION REACTIONS OF NUCLEOSIDE POLYPHOSPHATES. I. GENERAL FEATURES OF THE REACTION.

Authors:  D L VERHEYDEN; W E WEHRLI; J G MOFFATT
Journal:  J Am Chem Soc       Date:  1965-05-20       Impact factor: 15.419

2.  DISMUTATION REACTIONS OF NUCLEOSIDE POLYPHOSPHATES. IV. A MECHANISM FOR THE DISMUTATION REACTION.

Authors:  W E WEHRLI; J G MOFFATT
Journal:  J Am Chem Soc       Date:  1965-08-20       Impact factor: 15.419

3.  The free-energy changes associated with the individual steps of the tricarboxylic acid cycle, glycolysis and alcoholic fermentation and with the hydrolysis of the pyrophosphate groups of adenosinetriphosphate.

Authors:  K BURTON; H A KREBS
Journal:  Biochem J       Date:  1953-04       Impact factor: 3.857

4.  Formation of nucleoside 5'-polyphosphates from nucleotides and trimetaphosphate.

Authors:  R Lohrmann
Journal:  J Mol Evol       Date:  1975-12-29       Impact factor: 2.395

5.  Derivatization of unprotected polynucleotides.

Authors:  B C Chu; G M Wahl; L E Orgel
Journal:  Nucleic Acids Res       Date:  1983-09-24       Impact factor: 16.971

6.  Oligomerization of (guanosine 5'-phosphor)-2-methylimidazolide on poly(C). An RNA polymerase model.

Authors:  T Inoue; L E Orgel
Journal:  J Mol Biol       Date:  1982-11-25       Impact factor: 5.469

7.  Preparation of ligation intermediates and related polynucleotide pyrophosphates.

Authors:  B C Chu; L E Orgel
Journal:  Biochim Biophys Acta       Date:  1984-05-15

8.  A method for determining the positional isotope exchange in a nucleoside triphosphate: cyclization of nucleoside triphosphate by dicyclohexylcarbodiimide.

Authors:  M R Webb
Journal:  Biochemistry       Date:  1980-10-14       Impact factor: 3.162
  8 in total
  9 in total

1.  One-flask synthesis of dinucleoside tetra- and pentaphosphates.

Authors:  Qianwei Han; Barbara L Gaffney; Roger A Jones
Journal:  Org Lett       Date:  2006-05-11       Impact factor: 6.005

2.  Adenosine(5') oligophospho-(5') guanosines and guanosine(5') oligophospho-(5') guanosines in human platelets.

Authors:  H Schlüter; I Grobeta; J Bachmann; R Kaufmann; M van der Giet; M Tepel; J R Nofer; G Assmann; M Karas; J Jankowski; W Zidek
Journal:  J Clin Invest       Date:  1998-02-01       Impact factor: 14.808

3.  Disruption and overexpression of the Schizosaccharomyces pombe aps1 gene, and effects on growth rate, morphology and intracellular diadenosine 5',5"'-P1,P5-pentaphosphate and diphosphoinositol polyphosphate concentrations.

Authors:  Stephen W Ingram; Stephen T Safrany; Larry D Barnes
Journal:  Biochem J       Date:  2003-02-01       Impact factor: 3.857

4.  Characterization of the bis(5'-nucleosidyl) tetraphosphate pyrophosphohydrolase from encysted embryos of the brine shrimp Artemia.

Authors:  M Prescott; A D Milne; A G McLennan
Journal:  Biochem J       Date:  1989-05-01       Impact factor: 3.857

Review 5.  Beyond Triphosphates: Reagents and Methods for Chemical Oligophosphorylation.

Authors:  Scott M Shepard; Henning J Jessen; Christopher C Cummins
Journal:  J Am Chem Soc       Date:  2022-04-26       Impact factor: 16.383

6.  Uridine adenosine tetraphosphate acts as an autocrine hormone affecting glomerular filtration rate.

Authors:  V Jankowski; A Patzak; S Herget-Rosenthal; Thi Nguyet Anh Tran; En Yin Lai; T Günthner; I Buschmann; W Zidek; J Jankowski
Journal:  J Mol Med (Berl)       Date:  2008-02-05       Impact factor: 4.599

7.  Structure-activity relationships of dinucleotides: Potent and selective agonists of P2Y receptors.

Authors:  Sammy R Shaver; Janet L Rideout; William Pendergast; James G Douglass; Edward G Brown; José L Boyer; Roshni I Patel; Catherine C Redick; Arthur C Jones; Maryse Picher; Benjamin R Yerxa
Journal:  Purinergic Signal       Date:  2005-03-07       Impact factor: 3.765

8.  Identification of a potent endothelium-derived angiogenic factor.

Authors:  Vera Jankowski; Markus Tölle; Thi Nguyet Anh Tran; Markus van der Giet; Mirjam Schuchardt; Kerstin Lehmann; Doreen Janke; Burkhard Flick; Alberto Ortiz; Alberto Arduan Ortiz; Maria D Sanchez-Niño; Niño Maria Dolores Sanchez; Martin Tepel; Walter Zidek; Joachim Jankowski
Journal:  PLoS One       Date:  2013-07-29       Impact factor: 3.240

Review 9.  Synthetic Strategies for Dinucleotides Synthesis.

Authors:  Lucie Appy; Crystalle Chardet; Suzanne Peyrottes; Béatrice Roy
Journal:  Molecules       Date:  2019-11-27       Impact factor: 4.411
  9 in total

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