Literature DB >> 30288489

Editorial: Translational Control of APP Expression for Alzheimer Disease Therapy.

Joanna E Pankiewicz1,2, Martin J Sadowski1,3,2.   

Abstract

Entities:  

Keywords:  Alzheimer’s disease; amyloid precursor protein; messenger RNA; protein translation; therapy; β-amyloid

Year:  2017        PMID： 30288489      PMCID： PMC6168206     

Source DB:  PubMed          Journal:  Ann Pharmacol Pharm        ISSN： 2573-6051


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  15 in total

1.  Alzheimer's failure raises questions about disease-modifying strategies.

Authors:  Andy Extance
Journal:  Nat Rev Drug Discov       Date:  2010-10       Impact factor: 84.694

2.  Synaptic activity regulates interstitial fluid amyloid-beta levels in vivo.

Authors:  John R Cirrito; Kelvin A Yamada; Mary Beth Finn; Robert S Sloviter; Kelly R Bales; Patrick C May; Darryle D Schoepp; Steven M Paul; Steven Mennerick; David M Holtzman
Journal:  Neuron       Date:  2005-12-22       Impact factor: 17.173

3.  Neuronal deficiency of presenilin 1 inhibits amyloid plaque formation and corrects hippocampal long-term potentiation but not a cognitive defect of amyloid precursor protein [V717I] transgenic mice.

Authors:  Ilse Dewachter; Delphine Reversé; Nathalie Caluwaerts; Laurence Ris; Cuno Kuipéri; Chris Van den Haute; Kurt Spittaels; Lieve Umans; Lutgarde Serneels; Els Thiry; Dieder Moechars; Mark Mercken; Emile Godaux; Fred Van Leuven
Journal:  J Neurosci       Date:  2002-05-01       Impact factor: 6.167

4.  RNA therapeutics directed to the non coding regions of APP mRNA, in vivo anti-amyloid efficacy of paroxetine, erythromycin, and N-acetyl cysteine.

Authors:  Stephanie Tucker; Michelle Ahl; Hyun-Hee Cho; Sanghamitra Bandyopadhyay; Gregory D Cuny; Ashley I Bush; Lee E Goldstein; David Westaway; Xudong Huang; Jack T Rogers
Journal:  Curr Alzheimer Res       Date:  2006-07       Impact factor: 3.498

Review 5.  Physiological functions of APP family proteins.

Authors:  Ulrike C Müller; Hui Zheng
Journal:  Cold Spring Harb Perspect Med       Date:  2012-02       Impact factor: 6.915

6.  2014 Alzheimer's disease facts and figures.

Authors: 
Journal:  Alzheimers Dement       Date:  2014-03       Impact factor: 21.566

7.  FDA-preapproved drugs targeted to the translational regulation and processing of the amyloid precursor protein.

Authors:  Lee Jae Morse; Sandra M Payton; Gregory D Cuny; Jack T Rogers
Journal:  J Mol Neurosci       Date:  2004       Impact factor: 3.444

Review 8.  Alzheimer's disease therapeutics targeted to the control of amyloid precursor protein translation: maintenance of brain iron homeostasis.

Authors:  Sanghamitra Bandyopadhyay; Jack T Rogers
Journal:  Biochem Pharmacol       Date:  2014-02-07       Impact factor: 5.858

9.  Comparative analysis of single and combined APP/APLP knockouts reveals reduced spine density in APP-KO mice that is prevented by APPsα expression.

Authors:  Sascha W Weyer; Marta Zagrebelsky; Ulrike Herrmann; Meike Hick; Lennard Ganss; Julia Gobbert; Morna Gruber; Christine Altmann; Martin Korte; Thomas Deller; Ulrike C Müller
Journal:  Acta Neuropathol Commun       Date:  2014-03-31       Impact factor: 7.801

10.  Posiphen as a candidate drug to lower CSF amyloid precursor protein, amyloid-β peptide and τ levels: target engagement, tolerability and pharmacokinetics in humans.

Authors:  Maria L Maccecchini; Mee Young Chang; Catherine Pan; Varghese John; Henrik Zetterberg; Nigel H Greig
Journal:  J Neurol Neurosurg Psychiatry       Date:  2012-07-11       Impact factor: 10.154
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