Literature DB >> 3028647

Deletion analysis of GAL4 defines two transcriptional activating segments.

J Ma, M Ptashne.   

Abstract

We describe the activities of a wide array of deletion mutants of GAL4, a yeast transcriptional activator. We identify two short regions of GAL4, each of which activates transcription when fused to the DNA-binding region of the molecule. Very large portions of GAL4 are not required for gene activation.

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Year:  1987        PMID： 3028647     DOI： 10.1016/0092-8674(87)90081-x

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  356 in total

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Authors:  T Sakamoto; A Nishimura; M Tamaoki; M Kuba; H Tanaka; S Iwahori; M Matsuoka
Journal:  Plant Cell       Date:  1999-08       Impact factor: 11.277

2.  Context-dependent modulation of replication activity of Saccharomyces cerevisiae autonomously replicating sequences by transcription factors.

Authors:  H Kohzaki; Y Ito; Y Murakami
Journal:  Mol Cell Biol       Date:  1999-11       Impact factor: 4.272

3.  Transcriptional activation by artificial recruitment in yeast is influenced by promoter architecture and downstream sequences.

Authors:  L Gaudreau; M Keaveney; J Nevado; Z Zaman; G O Bryant; K Struhl; M Ptashne
Journal:  Proc Natl Acad Sci U S A       Date:  1999-03-16       Impact factor: 11.205

4.  H2A.Z is required for global chromatin integrity and for recruitment of RNA polymerase II under specific conditions.

Authors:  M Adam; F Robert; M Larochelle; L Gaudreau
Journal:  Mol Cell Biol       Date:  2001-09       Impact factor: 4.272

5.  SAGA is an essential in vivo target of the yeast acidic activator Gal4p.

Authors:  S R Bhaumik; M R Green
Journal:  Genes Dev       Date:  2001-08-01       Impact factor: 11.361

6.  Recruitment of the transcriptional machinery through GAL11P: structure and interactions of the GAL4 dimerization domain.

Authors:  P Hidalgo; A Z Ansari; P Schmidt; B Hare; N Simkovich; S Farrell; E J Shin; M Ptashne; G Wagner
Journal:  Genes Dev       Date:  2001-04-15       Impact factor: 11.361

7.  RNA sequences that work as transcriptional activating regions.

Authors:  Shamol Saha; Aseem Z Ansari; Kevin A Jarrell; Mark Ptashne; Kevin A Jarell
Journal:  Nucleic Acids Res       Date:  2003-03-01       Impact factor: 16.971

8.  lir-2, lir-1 and lin-26 encode a new class of zinc-finger proteins and are organized in two overlapping operons both in Caenorhabditis elegans and in Caenorhabditis briggsae.

Authors:  P Dufourcq; P Chanal; S Vicaire; E Camut; S Quintin; B G den Boer; J M Bosher; M Labouesse
Journal:  Genetics       Date:  1999-05       Impact factor: 4.562

9.  Interaction between transcriptional activator protein LAC9 and negative regulatory protein GAL80.

Authors:  J M Salmeron; S D Langdon; S A Johnston
Journal:  Mol Cell Biol       Date:  1989-07       Impact factor: 4.272

10.  The activation domain of GAL4 protein mediates cooperative promoter binding with general transcription factors in vivo.

Authors:  S Vashee; T Kodadek
Journal:  Proc Natl Acad Sci U S A       Date:  1995-11-07       Impact factor: 11.205
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