OBJECTIVES: We aimed to examine the impact of a point-of-care (POC) test on overtreatment and undertreatment of sexually transmitted infections (STIs) by comparing treatment patterns for gonorrhoea (detected with nucleic acid amplification testing (NAAT)) with trichomoniasis (detected by POC test) for young women seen in an emergency department (ED). METHODS: We reviewed the database of a quality improvement (QI) project that aims to improve follow-up care for STIs in the ED. Data included the test result and antibiotic given (if any) during visits by women age 14-21 for whom an STI test was ordered. We generated Shewhart control charts and compared overtreatment and undertreatment rates for gonorrhoea and trichomoniasis using χ(2) testing. RESULTS: Of 1877 visits over 18 months, 8.8% of women had gonorrhoea and 16.5% had trichomoniasis. Overtreatment was higher for women with gonorrhoea than trichomoniasis (54% vs 23%, p<0.001). Overtreatment for gonorrhoea decreased from 58% to 47% (p<0.01) and overtreatment for trichomoniasis decreased from 24% to 18% (p<0.01), which corresponded to improvements in patient follow-up for the QI project. Undertreatment was higher for women with gonorrhoea than trichomoniasis (29% vs 21%, p=0.03), and did not change over time. CONCLUSIONS: A POC test improves the accuracy of STI care in an ED compared with NAAT testing. An unanticipated benefit of QI efforts to improve patient follow-up is the observed decrease in antibiotic use in the ED. Given the ability of gonorrhoea to develop antibiotic resistance, future efforts should focus on development of an accurate POC test for gonorrhoea.
OBJECTIVES: We aimed to examine the impact of a point-of-care (POC) test on overtreatment and undertreatment of sexually transmitted infections (STIs) by comparing treatment patterns for gonorrhoea (detected with nucleic acid amplification testing (NAAT)) with trichomoniasis (detected by POC test) for young women seen in an emergency department (ED). METHODS: We reviewed the database of a quality improvement (QI) project that aims to improve follow-up care for STIs in the ED. Data included the test result and antibiotic given (if any) during visits by women age 14-21 for whom an STI test was ordered. We generated Shewhart control charts and compared overtreatment and undertreatment rates for gonorrhoea and trichomoniasis using χ(2) testing. RESULTS: Of 1877 visits over 18 months, 8.8% of women had gonorrhoea and 16.5% had trichomoniasis. Overtreatment was higher for women with gonorrhoea than trichomoniasis (54% vs 23%, p<0.001). Overtreatment for gonorrhoea decreased from 58% to 47% (p<0.01) and overtreatment for trichomoniasis decreased from 24% to 18% (p<0.01), which corresponded to improvements in patient follow-up for the QI project. Undertreatment was higher for women with gonorrhoea than trichomoniasis (29% vs 21%, p=0.03), and did not change over time. CONCLUSIONS: A POC test improves the accuracy of STI care in an ED compared with NAAT testing. An unanticipated benefit of QI efforts to improve patient follow-up is the observed decrease in antibiotic use in the ED. Given the ability of gonorrhoea to develop antibiotic resistance, future efforts should focus on development of an accurate POC test for gonorrhoea.
Entities:
Keywords:
ADOLESCENT; CLINICAL STI CARE; GONORRHOEA; TREATMENT; TRICHOMONAS
Authors: Lindi Masson; Kelly B Arnold; Francesca Little; Koleka Mlisana; David A Lewis; Nonhlanhla Mkhize; Hoyam Gamieldien; Sinaye Ngcapu; Leigh Johnson; Douglas A Lauffenburger; Quarraisha Abdool Karim; Salim S Abdool Karim; Jo-Ann S Passmore Journal: Sex Transm Infect Date: 2015-10-28 Impact factor: 3.519
Authors: Judith W Dexheimer; Huaxiu Tang; Andrea Kachelmeyer; Melanie Hounchell; Stephanie Kennebeck; Imre Solti; Yizhao Ni Journal: Pediatr Emerg Care Date: 2019-12 Impact factor: 1.454
Authors: Jennifer L Reed; Jill S Huppert; Regina G Taylor; Gordon L Gillespie; Terri L Byczkowski; Jessica A Kahn; Evaline A Alessandrini Journal: J Adolesc Health Date: 2014-06-21 Impact factor: 5.012
Authors: Lea E Widdice; Yu-Hsiang Hsieh; Barbara Silver; Mathilda Barnes; Perry Barnes; Charlotte A Gaydos Journal: Sex Transm Dis Date: 2018-11 Impact factor: 2.830
Authors: Bhakti Hansoti; Anant Mishra; Aditi Rao; Lucy Chimoyi; Andrew D Redd; Steven J Reynolds; David F Stead; John Black; Roshen Maharaj; Elizabeth Hahn; Pamela Mda; Nomzamo Mvandaba; Yandisa Nyanisa; Victoria Chen; Katie Clark; Sofia Ryan; Thomas C Quinn Journal: EClinicalMedicine Date: 2021-08-19