| Literature DB >> 30239069 |
Jessica L Saben1,2, Shelby K Shelton1,2, Andrew J Hopkinson1,2, Brandon J Sonn1,2,3, Eleanor B Mills1,2, Makayla Welham1,2, Megan Westmoreland1,2,3, Richard Zane1,2, Adit A Ginde1,2, Kelly Bookman1,2, Justin Oeth1, Mark Chavez1, Michael DeVivo1, Alison Lakin4, John Heldens4,5, Laurie Blumberg Romero1, Michael J Ames1,6, Emily R Roberts7, Matthew Taylor1,6,7,8, Kristy Crooks1,6,9,7, Stephen J Wicks7, Kathleen C Barnes1,6,7, Andrew A Monte1,2,7,3.
Abstract
The Emergency Medicine Specimen Bank (EMSB) was developed to facilitate precision medicine in acute care. The EMSB is a biorepository of clinical health data and biospecimens collected from all adult English- or Spanish-speaking individuals who are able and willing to provide consent and are treated at the UCHealth-University of Colorado Hospital Emergency Department. The EMSB is the first acute care biobank that seeks to enroll all patients, with all conditions who present to the ED. Acute care biobanking presents many challenges that are unique to acute care settings such as providing informed consent in a uniquely stressful and fast-paced environment and collecting, processing, and storing samples for tens of thousands of patients per year. Here, we describe the process by which the EMSB overcame these challenges and was integrated into clinical workflow allowing for operation 24 hours a day, 7 days a week at a reasonable cost. Other institutions can implement this template, further increasing the power of biobanking research to inform treatment strategies and interventions for common and uncommon phenotypes in acute care settings.Entities:
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Year: 2018 PMID： 30239069 PMCID： PMC6428625 DOI： 10.1111/acem.13620
Source DB: PubMed Journal: Acad Emerg Med ISSN： 1069-6563 Impact factor: 3.451