Literature DB >> 3023708

Mammary tumorigenesis in feral mice: identification of a new int locus in mouse mammary tumor virus (Czech II)-induced mammary tumors.

D Gallahan, R Callahan.   

Abstract

A population of Mus musculus subsp. musculus (Czech II), recently isolated from the wild, lack endogenous mouse mammary tumor virus (MMTV) proviral genomes. Some of these mice carry an infectious MMTV [designated MMTV (Czech II)] that is transmitted in the milk and is associated with mammary tumor development. This virus is distinct from laboratory strains of MMTV present in inbred mice. An MMTV (Czech II) genome was found within a 0.5-kilobase region of the cellular genome in five of 16 Czech II mammary tumors. MMTV insertion at this site activates expression of a 2.4-kilobase species of RNA from a previously silent cellular gene. This region of the cellular genome was designated int-3 since it is unrelated to the int-1 and int-2 loci. The int-3 locus does not appear to correspond to other proto-oncogenes but is well conserved among mammalian species.

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Year:  1987        PMID： 3023708      PMCID： PMC255203     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  31 in total

1.  Specific integration of REV proviruses in avian bursal lymphomas.

Authors:  M R Noori-Daloii; R A Swift; H J Kung; L B Crittenden; R L Witter
Journal:  Nature       Date:  1981-12-10       Impact factor: 49.962

2.  Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis.

Authors:  W S Hayward; B G Neel; S M Astrin
Journal:  Nature       Date:  1981-04-09       Impact factor: 49.962

3.  Mouse mammary tumor virus integration regions int-1 and int-2 map on different mouse chromosomes.

Authors:  G Peters; C Kozak; C Dickson
Journal:  Mol Cell Biol       Date:  1984-02       Impact factor: 4.272

4.  Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome.

Authors:  R Nusse; H E Varmus
Journal:  Cell       Date:  1982-11       Impact factor: 41.582

5.  Restriction endonuclease mapping of the proviral DNA of the exogenous RIII murine mammary tumor virus.

Authors:  P R Etkind; P Szabo; N H Sarkar
Journal:  J Virol       Date:  1982-03       Impact factor: 5.103

6.  Novel class of mouse mammary tumor virus-related DNA sequences found in all species of Mus, including mice lacking the virus proviral genome.

Authors:  R Callahan; W Drohan; D Gallahan; L D'Hoostelaere; M Potter
Journal:  Proc Natl Acad Sci U S A       Date:  1982-07       Impact factor: 11.205

7.  Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15.

Authors:  R Nusse; A van Ooyen; D Cox; Y K Fung; H Varmus
Journal:  Nature       Date:  1984 Jan 12-18       Impact factor: 49.962

8.  Activation of the cellular oncogene c-erbB by LTR insertion: molecular basis for induction of erythroblastosis by avian leukosis virus.

Authors:  Y K Fung; W G Lewis; L B Crittenden; H J Kung
Journal:  Cell       Date:  1983-06       Impact factor: 41.582

9.  A common region for proviral DNA integration in MoMuLV-induced rat thymic lymphomas.

Authors:  P N Tsichlis; P G Strauss; L F Hu
Journal:  Nature       Date:  1983 Mar 31-Apr 6       Impact factor: 49.962

10.  Tumorigenesis by mouse mammary tumor virus: evidence for a common region for provirus integration in mammary tumors.

Authors:  G Peters; S Brookes; R Smith; C Dickson
Journal:  Cell       Date:  1983-06       Impact factor: 41.582
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  85 in total

1.  Notch signaling is essential for vascular morphogenesis in mice.

Authors:  L T Krebs; Y Xue; C R Norton; J R Shutter; M Maguire; J P Sundberg; D Gallahan; V Closson; J Kitajewski; R Callahan; G H Smith; K L Stark; T Gridley
Journal:  Genes Dev       Date:  2000-06-01       Impact factor: 11.361

2.  Dll4, a novel Notch ligand expressed in arterial endothelium.

Authors:  J R Shutter; S Scully; W Fan; W G Richards; J Kitajewski; G A Deblandre; C R Kintner; K L Stark
Journal:  Genes Dev       Date:  2000-06-01       Impact factor: 11.361

3.  Notch signaling during vascular development.

Authors:  T Gridley
Journal:  Proc Natl Acad Sci U S A       Date:  2001-05-08       Impact factor: 11.205

4.  Mouse Mammary Tumor Virus Proviral Integration in the DD/Tbr Mice.

Authors: 
Journal:  Breast Cancer       Date:  1994-07-30       Impact factor: 4.239

5.  Complete Nucleotide Sequence of Mouse Mammary Tumor Virus from JYG Chinese Wild Mice: Absence of Bacterial Insertion Sequences in the Cloned Viral gag Gene.

Authors: 
Journal:  Breast Cancer       Date:  1994-12-30       Impact factor: 4.239

6.  New murine mammary tumor cell lines.

Authors:  J Morimoto; S Imai; S Haga; Y Iwai; M Iwai; S Hiroishi; N Miyashita; K Moriwaki; H L Hosick
Journal:  In Vitro Cell Dev Biol       Date:  1991-05

Review 7.  Identifying and targeting tumor-initiating cells in the treatment of breast cancer.

Authors:  Wei Wei; Michael T Lewis
Journal:  Endocr Relat Cancer       Date:  2015-04-15       Impact factor: 5.678

8.  Mouse mammary tumor proviruses from a T-cell lymphoma are associated with the retroposon L1Md.

Authors:  J P Dudley
Journal:  J Virol       Date:  1988-02       Impact factor: 5.103

9.  Expression of the int-1 and int-2 loci in endogenous mouse mammary tumor virus-induced mammary tumorigenesis in the C3Hf mouse.

Authors:  P R Etkind
Journal:  J Virol       Date:  1989-11       Impact factor: 5.103

Review 10.  Premalignant and malignant mammary lesions induced by MMTV and chemical carcinogens.

Authors:  Daniel Medina
Journal:  J Mammary Gland Biol Neoplasia       Date:  2008-07-29       Impact factor: 2.673
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