Literature DB >> 6321961

Mouse mammary tumor virus integration regions int-1 and int-2 map on different mouse chromosomes.

G Peters, C Kozak, C Dickson.   

Abstract

Two regions of mouse DNA which constitute common provirus integration sites in tumors induced by mouse mammary tumor virus have been identified and designated int-1 and int-2. By examining a series of hamster-mouse somatic cell hybrids, we mapped the int-2 locus to mouse chromosome 7 and confirmed the previous assignment of int-1 to chromosome 15. This constitutes proof that int-1 and int-2 are discrete genetic loci. It is therefore possible that proviral activation of two distinct cellular genes may result in the same neoplastic disease.

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Year:  1984        PMID： 6321961      PMCID： PMC368706          DOI： 10.1128/mcb.4.2.375-378.1984

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  21 in total

1.  Genetic mapping of the ecotropic murine leukemia virus-inducing locus of BALB/c mouse to chromosome 5.

Authors:  C A Kozak; W P Rowe
Journal:  Science       Date:  1979-04-06       Impact factor: 47.728

2.  Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis.

Authors:  W S Hayward; B G Neel; S M Astrin
Journal:  Nature       Date:  1981-04-09       Impact factor: 49.962

Review 3.  Use of transfection to analyze genetic information and malignant transformation.

Authors:  R A Weinberg
Journal:  Biochim Biophys Acta       Date:  1981-08-31

4.  Gene linkage analysis in the mouse by somatic cell hybridization: assignment of adenine phosphoribosyltransferase to chromosome 8 and alpha-galactosidase to the X chromosome.

Authors:  C Kozak; E Nichols; F H Ruddle
Journal:  Somatic Cell Genet       Date:  1975-10

5.  Integration of the DNA of mouse mammary tumor virus in virus-infected normal and neoplastic tissue of the mouse.

Authors:  J C Cohen; P R Shank; V L Morris; R Cardiff; H E Varmus
Journal:  Cell       Date:  1979-02       Impact factor: 41.582

6.  A cellular oncogene (c-Ki-ras) is amplified, overexpressed, and located within karyotypic abnormalities in mouse adrenocortical tumour cells.

Authors:  M Schwab; K Alitalo; H E Varmus; J M Bishop; D George
Journal:  Nature       Date:  1983 Jun 9-15       Impact factor: 49.962

7.  Tumorigenesis by mouse mammary tumor virus: evidence for a common region for provirus integration in mammary tumors.

Authors:  G Peters; S Brookes; R Smith; C Dickson
Journal:  Cell       Date:  1983-06       Impact factor: 41.582

8.  On the mechanism of retrovirus-induced avian lymphoid leukosis: deletion and integration of the proviruses.

Authors:  Y K Fung; A M Fadly; L B Crittenden; H J Kung
Journal:  Proc Natl Acad Sci U S A       Date:  1981-06       Impact factor: 11.205

9.  Genetic mapping of the ecotropic virus-inducing locus Akv-2 of the AKR mouse.

Authors:  C A Kozak; W P Rowe
Journal:  J Exp Med       Date:  1980-11-01       Impact factor: 14.307

10.  Localization of a gene for expression of mouse mammary tumor virus antigens in the GR/Mtv-2- mouse strain.

Authors:  R Nusse; J de Moes; J Hilkens; R van Nie
Journal:  J Exp Med       Date:  1980-09-01       Impact factor: 14.307
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  32 in total

Review 1.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M R Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

Review 2.  Mouse chromosome 15.

Authors:  B A Mock; P E Neumann; J T Eppig; K E Huppi
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

3.  Chromosomal localizations of mouse Fgf2 and Fgf5 genes.

Authors:  M G Mattei; M J Pébusque; D Birnbaum
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

Review 4.  Mouse chromosome 15.

Authors:  B Mock; P E Neumann; J T Eppig; K Huppi
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

Review 5.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

6.  Of worms and men: an evolutionary perspective on the fibroblast growth factor (FGF) and FGF receptor families.

Authors:  F Coulier; P Pontarotti; R Roubin; H Hartung; M Goldfarb; D Birnbaum
Journal:  J Mol Evol       Date:  1997-01       Impact factor: 2.395

7.  Two proto-oncogenes implicated in mammary carcinogenesis, int-1 and int-2, are independently regulated during mouse development.

Authors:  A Jakobovits; G M Shackleford; H E Varmus; G R Martin
Journal:  Proc Natl Acad Sci U S A       Date:  1986-10       Impact factor: 11.205

Review 8.  Viruses associated with human cancer.

Authors:  Margaret E McLaughlin-Drubin; Karl Munger
Journal:  Biochim Biophys Acta       Date:  2007-12-23

Review 9.  Genetic alterations in primary breast cancer.

Authors:  R Callahan
Journal:  Breast Cancer Res Treat       Date:  1989-07       Impact factor: 4.872

10.  Mouse chromosomal mapping of a murine leukemia virus integration region (Mis-1) first identified in rat thymic leukemia.

Authors:  P Jolicoeur; L Villeneuve; E Rassart; C Kozak
Journal:  J Virol       Date:  1985-12       Impact factor: 5.103
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