Literature DB >> 30216232

The Frequency of Discordant Gyrase A Genotypes Among Cases of Multiple Neisseria gonorrhoeae Infections at Different Anatomic Sites.

Lao-Tzu Allan-Blitz1, Olivia L Ellis, Robert Bolan2, Peera Hemarajata3, Romney M Humphries, Akbar Shahkolahi4, Mark McGrath5, Jeffrey D Klausner.   

Abstract

Gyrase A genotyping reliably predicts Neisseria gonorrhoeae susceptibility to ciprofloxacin. It is unknown whether concurrent infections at different anatomic sites harbor different susceptibility profiles. We found a 3.2% frequency of discordant gyrase A genotypes among concurrent but anatomically separate N. gonorrhoeae infections diagnosed at 2 laboratories in Los Angeles.

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Year:  2019        PMID： 30216232      PMCID： PMC6289622          DOI： 10.1097/OLQ.0000000000000912

Source DB:  PubMed          Journal:  Sex Transm Dis        ISSN： 0148-5717            Impact factor:   2.830


  9 in total

Review 1.  Wild-Type Gyrase A Genotype of Neisseria gonorrhoeae Predicts In Vitro Susceptibility to Ciprofloxacin: A Systematic Review of the Literature and Meta-Analysis.

Authors:  Lao-Tzu Allan-Blitz; Xiaoyan Wang; Jeffrey D Klausner
Journal:  Sex Transm Dis       Date:  2017-05       Impact factor: 2.830

2.  The antibiotic resistance crisis: part 1: causes and threats.

Authors:  C Lee Ventola
Journal:  P T       Date:  2015-04

3.  Implementation of a Rapid Genotypic Assay to Promote Targeted Ciprofloxacin Therapy of Neisseria gonorrhoeae in a Large Health System.

Authors:  Lao-Tzu Allan-Blitz; Romney M Humphries; Peera Hemarajata; Ashima Bhatti; Mark W Pandori; Mark J Siedner; Jeffrey D Klausner
Journal:  Clin Infect Dis       Date:  2017-05-01       Impact factor: 9.079

4.  Genetic typing of the porin protein of Neisseria gonorrhoeae from clinical noncultured samples for strain characterization and identification of mixed gonococcal infections.

Authors:  Freyja Lynn; Marcia M Hobbs; Jonathan M Zenilman; Frieda M T F Behets; Kathleen Van Damme; Andry Rasamindrakotroka; Margaret C Bash
Journal:  J Clin Microbiol       Date:  2005-01       Impact factor: 5.948

5.  Detection of mixed infection of Neisseria gonorrhoeae.

Authors:  I M C Martin; C A Ison
Journal:  Sex Transm Infect       Date:  2003-02       Impact factor: 3.519

Review 6.  Molecular tests for the detection of antimicrobial resistant Neisseria gonorrhoeae: when, where, and how to use?

Authors:  Nicola Low; Magnus Unemo
Journal:  Curr Opin Infect Dis       Date:  2016-02       Impact factor: 4.915

7.  Performance and Verification of a Real-Time PCR Assay Targeting the gyrA Gene for Prediction of Ciprofloxacin Resistance in Neisseria gonorrhoeae.

Authors:  P Hemarajata; S Yang; O O Soge; R M Humphries; J D Klausner
Journal:  J Clin Microbiol       Date:  2016-01-06       Impact factor: 5.948

8.  Antimicrobial resistance in Neisseria gonorrhoeae: Global surveillance and a call for international collaborative action.

Authors:  Teodora Wi; Monica M Lahra; Francis Ndowa; Manju Bala; Jo-Anne R Dillon; Pilar Ramon-Pardo; Sergey R Eremin; Gail Bolan; Magnus Unemo
Journal:  PLoS Med       Date:  2017-07-07       Impact factor: 11.069

9.  Accurate detection of Neisseria gonorrhoeae ciprofloxacin susceptibility directly from genital and extragenital clinical samples: towards genotype-guided antimicrobial therapy.

Authors:  Marcus J Pond; Catherine L Hall; Victoria F Miari; Michelle Cole; Ken G Laing; Heena Jagatia; Emma Harding-Esch; Irene M Monahan; Timothy Planche; Jason Hinds; Catherine A Ison; Stephanie Chisholm; Philip D Butcher; Syed Tariq Sadiq
Journal:  J Antimicrob Chemother       Date:  2016-01-26       Impact factor: 5.790
  9 in total

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