Literature DB >> 3019774

Inositol phosphate production following alpha 1-adrenergic, muscarinic or electrical stimulation in isolated rat heart.

J Poggioli, J C Sulpice, G Vassort.   

Abstract

A possible participation of polyphosphoinositide metabolism in the excitation-contraction coupling in heart was investigated. Isolated rat ventricles prelabelled with myo-[2-3H]inositol were stimulated by conditions that increase mechanical activity. Both noradrenaline and carbachol increased the basal level of IP3, IP2 and IP by the activation of alpha 1-adrenergic and muscarinic receptors, respectively. Electrical stimulation accelerated inositol lipid degradation by phospholipase C thus enhancing the IP3 level as compared to quiescent ventricles. It is proposed that IP3 may be involved in excitation-contraction coupling in cardiac tissue.

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Year:  1986        PMID： 3019774     DOI： 10.1016/0014-5793(86)80999-1

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  36 in total

1.  Effect of calcium overload on the phosphoinositide breakdown in the rat left ventricular papillary muscle.

Authors:  H Otani; H Otani; M Morita; D K Das
Journal:  Mol Cell Biochem       Date:  1989-10-31       Impact factor: 3.396

2.  Modulation of cytosolic free calcium concentration by alpha 1-adrenoceptors in rat atrial cells.

Authors:  U Jahnel; H Nawrath; R C Shieh; V K Sharma; D J Williford; S S Sheu
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1992-07       Impact factor: 3.000

3.  The cardiac IP3 receptor: uncovering the role of "the other" calcium-release channel.

Authors:  Thomas J Hund; Andrew P Ziman; W J Lederer; Peter J Mohler
Journal:  J Mol Cell Cardiol       Date:  2008-06-13       Impact factor: 5.000

4.  Effects of pertussis toxin on alpha 1-agonist-mediated phosphatidylinositide turnover and myocardial cell hypertrophy in neonatal rat ventricular myocytes.

Authors:  J S Karliner; T Kagiya; P C Simpson
Journal:  Experientia       Date:  1990-01-15

5.  Effects of sympathetic nerve stimulation on membrane potential, [Ca2+]i and force in the arrested sinus venosus of the toad, Bufo marinus.

Authors:  H M Cousins; N J Bramich
Journal:  J Physiol       Date:  1997-12-01       Impact factor: 5.182

6.  Alpha-1-adrenergic stimulation of phosphoinositide breakdown in cultured neonatal rat ventricular myocytes.

Authors:  J T Meij; J M Lamers
Journal:  Mol Cell Biochem       Date:  1989 Jun 27-Jul 24       Impact factor: 3.396

7.  Discrete interactions between phosphatidylethanolamine-N-methylation and phosphatidylinositolbisphosphate hydrolysis in rat myocardium.

Authors:  J T Meij; G Paolillo; K Bezstarosti; P D Verdouw; V Panagia; J M Lamers
Journal:  Mol Cell Biochem       Date:  1989-10-31       Impact factor: 3.396

Review 8.  On the mechanism of positive inotropic effects of alpha-adrenoceptor agonists.

Authors:  W Schmitz; C Kohl; J Neumann; H Scholz; J Scholz
Journal:  Basic Res Cardiol       Date:  1989       Impact factor: 17.165

9.  ATP and other adenine compounds increase mechanical activity and inositol trisphosphate production in rat heart.

Authors:  A Legssyer; J Poggioli; D Renard; G Vassort
Journal:  J Physiol       Date:  1988-07       Impact factor: 5.182

10.  Protein kinase C enhances myosin light-chain kinase effects on force development and ATPase activity in rat single skinned cardiac cells.

Authors:  O Clement; M Puceat; M P Walsh; G Vassort
Journal:  Biochem J       Date:  1992-07-01       Impact factor: 3.857
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