| Literature DB >> 2153573 |
J S Karliner1, T Kagiya, P C Simpson.
Abstract
In neonatal rat ventricular myocytes pretreatment with pertussis toxin did not affect 1 microM (-)-norepinephrine stimulation of inositol phosphates or myocardial cell hypertrophy as measured either by protein radiolabelling or by myocardial cell protein content. Thus guanine nucleotide protein(s) ADP-ribosylated by pertussis toxin do not play a role in two alpha 1-adrenoceptor-mediated processes, phosphatidylinositide turnover and induction of myocardial cell hypertrophy.Entities:
Mesh:
Substances:
Year: 1990 PMID: 2153573 DOI: 10.1007/bf01955423
Source DB: PubMed Journal: Experientia ISSN: 0014-4754