Literature DB >> 30184186

Expanding home-based management of malaria to all age groups in Rwanda: analysis of acceptability and facility-level time-series data.

Aline Uwimana1, Michael J Penkunas2, Marie Paul Nisingizwe2, Didier Uyizeye3, Dieudonne Hakizimana2, Clarisse Musanabaganwa4, Jean Pierre Musabyimana4, Alida Ngwije2, Innocent Turate5, Aimable Mbituyumuremyi1, Monique Murindahabi1, Jeanine Condo6.   

Abstract

Background: In response to a resurgence of malaria in Rwanda, home-based management (HBM) was expanded to enable community-health workers (CHWs) to provide malaria treatment to patients of all ages. We assessed the effect of the expanded HBM program on malaria case presentations at health facilities.
Methods: Services provided by CHWs and health facility presentations among individuals >5 y of age were considered. Presentations to CHWs were analyzed descriptively to assess acceptability and segmented regression modeling using facility-level data was employed to compare changes between the pre- and postintervention periods for intervention and control districts.
Results: Individuals >5 y of age readily accessed malaria diagnosis and treatment services from CHWs. Severe and uncomplicated malaria increased in the postintervention period for both the intervention and control districts. Presentations for uncomplicated malaria increased in the intervention and control districts to a similar degree. Severe cases increased to a greater degree in the intervention districts immediately after HBM was expanded compared with controls, but the monthly rate of increase was lower in the intervention districts. Conclusions: Services were shifted to CHWs, as demonstrated by the number of individuals treated through the expanded program. The rate of severe malaria increased immediately after implementation within intervention districts relative to controls, potentially because of enhanced case-finding. The rate of increase in severe cases was lower in the intervention districts comparatively, likely due to expedited treatment.

Entities:  

Mesh:

Substances:

Year:  2018        PMID: 30184186     DOI: 10.1093/trstmh/try093

Source DB:  PubMed          Journal:  Trans R Soc Trop Med Hyg        ISSN: 0035-9203            Impact factor:   2.184


  3 in total

1.  Changing Pattern of Plasmodium falciparum pfmdr1 Gene Polymorphisms in Southern Rwanda.

Authors:  Welmoed van Loon; Clara Bergmann; Felix Habarugira; Costanza Tacoli; Darius Savelsberg; Rafael Oliveira; Djibril Mbarushimana; Jules Ndoli; Augustin Sendegeya; Claude Bayingana; Frank P Mockenhaupt
Journal:  Antimicrob Agents Chemother       Date:  2021-08-17       Impact factor: 5.191

2.  Increase in Kelch 13 Polymorphisms in Plasmodium falciparum, Southern Rwanda.

Authors:  Clara Bergmann; Welmoed van Loon; Felix Habarugira; Costanza Tacoli; Julia C Jäger; Darius Savelsberg; Fabian Nshimiyimana; Elias Rwamugema; Djibril Mbarushimana; Jules Ndoli; Augustin Sendegeya; Claude Bayingana; Frank P Mockenhaupt
Journal:  Emerg Infect Dis       Date:  2021-01       Impact factor: 6.883

3.  How delayed and non-adherent treatment contribute to onward transmission of malaria: a modelling study.

Authors:  Joseph D Challenger; Bronner P Gonçalves; John Bradley; Katia Bruxvoort; Alfred B Tiono; Chris Drakeley; Teun Bousema; Azra C Ghani; Lucy C Okell
Journal:  BMJ Glob Health       Date:  2019-12-10
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.