Literature DB >> 30182863

Detection of East/Central/South African genotype Chikungunya virus during an outbreak in a southeastern state of Brazil.

C Lessa-Aquino1, K S Trinta1, C P Pestana1, M O Ribeiro1, M V F Sucupira1, M N Boia2, P A Baptista1, R V Cunha3, M A Medeiros1.   

Abstract

Chikungunya virus (CHIKV) is an arbovirus transmitted by Aedes mosquitoes that was first identified in Brazil in 2014. It causes a febrile illness characterised by severe arthralgia and rash. Our group investigated a suspected CHIKV outbreak in Governador Valadares, state of Minas Gerais, Brazil and from 25 acute-phase patients, 10 had qRT-PCR positive sera samples and had E1 partial sequence amplified and Sanger sequenced. Samples were identified as East/Central/South African (ECSA) genotype by phylogenetic analysis and clustered with CHIKV sequences isolated in the neighbour state of Bahia. Our findings confirm previous predictions that ECSA genotype would spread through northeast and southeast of Brazil.

Entities:  

Keywords:  Brazil; Chikungunya virus; genotype

Mesh：

Substances：

Year:  2018        PMID： 30182863      PMCID： PMC6453016          DOI： 10.1017/S0950268818002467

Source DB:  PubMed          Journal:  Epidemiol Infect        ISSN： 0950-2688            Impact factor:   4.434


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  4 in total

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