Literature DB >> 30171015

Targeting dihydroorotate dehydrogenase in acute myeloid leukemia.

Zhihong Zeng1, Marina Konopleva2,3.   

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Year:  2018        PMID： 30171015      PMCID： PMC6119147          DOI： 10.3324/haematol.2018.197806

Source DB:  PubMed          Journal:  Haematologica        ISSN： 0390-6078            Impact factor:   9.941


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  19 in total

1.  Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia.

Authors:  David B Sykes; Youmna S Kfoury; François E Mercier; Mathias J Wawer; Jason M Law; Mark K Haynes; Timothy A Lewis; Amir Schajnovitz; Esha Jain; Dongjun Lee; Hanna Meyer; Kerry A Pierce; Nicola J Tolliday; Anna Waller; Steven J Ferrara; Ashley L Eheim; Detlef Stoeckigt; Katrina L Maxcy; Julien M Cobert; Jacqueline Bachand; Brian A Szekely; Siddhartha Mukherjee; Larry A Sklar; Joanne D Kotz; Clary B Clish; Ruslan I Sadreyev; Paul A Clemons; Andreas Janzer; Stuart L Schreiber; David T Scadden
Journal:  Cell       Date:  2016-09-15       Impact factor: 41.582

Review 2.  MYC on the path to cancer.

Authors:  Chi V Dang
Journal:  Cell       Date:  2012-03-30       Impact factor: 41.582

3.  PTEN Regulates Glutamine Flux to Pyrimidine Synthesis and Sensitivity to Dihydroorotate Dehydrogenase Inhibition.

Authors:  Deepti Mathur; Elias Stratikopoulos; Sait Ozturk; Nicole Steinbach; Sarah Pegno; Sarah Schoenfeld; Raymund Yong; Vundavalli V Murty; John M Asara; Lewis C Cantley; Ramon Parsons
Journal:  Cancer Discov       Date:  2017-03-02       Impact factor: 39.397

Review 4.  Could BRAF mutations in melanocytic lesions arise from DNA damage induced by ultraviolet radiation?

Authors:  Nancy E Thomas; Marianne Berwick; Marila Cordeiro-Stone
Journal:  J Invest Dermatol       Date:  2006-08       Impact factor: 8.551

Review 5.  Management of acute promyelocytic leukemia: recommendations from an expert panel on behalf of the European LeukemiaNet.

Authors:  Miguel A Sanz; David Grimwade; Martin S Tallman; Bob Lowenberg; Pierre Fenaux; Elihu H Estey; Tomoki Naoe; Eva Lengfelder; Thomas Büchner; Hartmut Döhner; Alan K Burnett; Francesco Lo-Coco
Journal:  Blood       Date:  2008-09-23       Impact factor: 22.113

Review 6.  The biology of cancer: metabolic reprogramming fuels cell growth and proliferation.

Authors:  Ralph J DeBerardinis; Julian J Lum; Georgia Hatzivassiliou; Craig B Thompson
Journal:  Cell Metab       Date:  2008-01       Impact factor: 27.287

7.  Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML.

Authors:  Courtney D DiNardo; Eytan M Stein; Stéphane de Botton; Gail J Roboz; Jessica K Altman; Alice S Mims; Ronan Swords; Robert H Collins; Gabriel N Mannis; Daniel A Pollyea; Will Donnellan; Amir T Fathi; Arnaud Pigneux; Harry P Erba; Gabrielle T Prince; Anthony S Stein; Geoffrey L Uy; James M Foran; Elie Traer; Robert K Stuart; Martha L Arellano; James L Slack; Mikkael A Sekeres; Christophe Willekens; Sung Choe; Hongfang Wang; Vickie Zhang; Katharine E Yen; Stephanie M Kapsalis; Hua Yang; David Dai; Bin Fan; Meredith Goldwasser; Hua Liu; Sam Agresta; Bin Wu; Eyal C Attar; Martin S Tallman; Richard M Stone; Hagop M Kantarjian
Journal:  N Engl J Med       Date:  2018-06-02       Impact factor: 91.245

Review 8.  O-GlcNAcylation and Metabolic Reprograming in Cancer.

Authors:  Paweł Jóźwiak; Ewa Forma; Magdalena Bryś; Anna Krześlak
Journal:  Front Endocrinol (Lausanne)       Date:  2014-09-09       Impact factor: 5.555

Review 9.  Acute Myeloid Leukemia: A Concise Review.

Authors:  Jennifer N Saultz; Ramiro Garzon
Journal:  J Clin Med       Date:  2016-03-05       Impact factor: 4.241

10.  A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.

Authors:  Marcus J G W Ladds; Ingeborg M M van Leeuwen; Catherine J Drummond; Su Chu; Alan R Healy; Gergana Popova; Andrés Pastor Fernández; Tanzina Mollick; Suhas Darekar; Saikiran K Sedimbi; Marta Nekulova; Marijke C C Sachweh; Johanna Campbell; Maureen Higgins; Chloe Tuck; Mihaela Popa; Mireia Mayoral Safont; Pascal Gelebart; Zinayida Fandalyuk; Alastair M Thompson; Richard Svensson; Anna-Lena Gustavsson; Lars Johansson; Katarina Färnegårdh; Ulrika Yngve; Aljona Saleh; Martin Haraldsson; Agathe C A D'Hollander; Marcela Franco; Yan Zhao; Maria Håkansson; Björn Walse; Karin Larsson; Emma M Peat; Vicent Pelechano; John Lunec; Borivoj Vojtesek; Mar Carmena; William C Earnshaw; Anna R McCarthy; Nicholas J Westwood; Marie Arsenian-Henriksson; David P Lane; Ravi Bhatia; Emmet McCormack; Sonia Laín
Journal:  Nat Commun       Date:  2018-03-16       Impact factor: 14.919
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  1 in total

1.  A Combined Chemical, Computational, and In Vitro Approach Identifies SBL-105 as Novel DHODH Inhibitor in Acute Myeloid Leukemia Cells.

Authors:  Hossam Kamli; Gaffar S Zaman; Ahmad Shaikh; Abdullah A Mobarki; Prasanna Rajagopalan
Journal:  Oncol Res       Date:  2021-08-05       Impact factor: 5.574
  1 in total

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