Literature DB >> 30135615

Optical scanner for 3D radiotherapy polymer gel dosimetry.

Piotr Sobotka1, Marek Kozicki2, Piotr Maras3, Ł Boniecki1, K Kacperski4, A W Domański1.   

Abstract

Sophisticated techniques employed in radiotherapy for irradiation of tumours require comprehensive dosimetry allowing for precise, high resolution measurements of radiation dose distribution in three dimensions and verification of treatment planning systems. Polymer gel dosimetry has been shown to be a unique technique for three-dimensional high resolution measurements of absorbed radiation dose distributions. If exposed to ionizing radiation, radical polymerisation and crosslinking of monomeric components take place in a 3D polymer gel dosimeter, leading to the formation of large polymeric structures that scatter visible light. This feature allows for optical observation of the effects of the absorbed dose and its distribution. Presently, magnetic resonance imaging is employed the most often for analysis of 3D polymer gel dosimeters. However, much attention is also being given to the development of optical computed tomography since this technique is hoped to serve as a substitute for expensive and not easily available magnetic resonance imaging. The optical scanner presented in this work consists of a laser diode, a scanning system and a signal detector. A 3D polymer gel dosimeter is measured in an immersion liquid in order to reduce deflection of the light from the dosimeter phantom. The very first results were obtained with the newly constructed scanner for PABIGnx 3D polymer gel dosimeter, which was inhomogeneously irradiated with 192Ir brachytherapy source. The results have been contrasted with those for magnetic resonance imaging and are presented in this work together with the description of the optical scanner. Currently, optimization of the optical scanner is performed.

Entities:  

Year:  2012        PMID: 30135615      PMCID: PMC6101184          DOI: 10.12693/APhysPolA.122.969

Source DB:  PubMed          Journal:  Acta Phys Pol A        ISSN: 0587-4246            Impact factor:   0.577


  27 in total

1.  Wide dynamic dose range of VIPAR polymer gel dosimetry.

Authors:  P Kipouros; E Pappas; P Baras; D Hatzipanayoti; P Karaiskos; L Sakelliou; P Sandilos; I Seimenis
Journal:  Phys Med Biol       Date:  2001-08       Impact factor: 3.609

2.  Relative output factor measurements of a 5 mm diameter radiosurgical photon beam using polymer gel dosimetry.

Authors:  E Pappas; L Petrokokkinos; A Angelopoulos; T G Maris; M Kozicki; I Dalezios; V Kouloulias
Journal:  Med Phys       Date:  2005-06       Impact factor: 4.071

3.  Dose-response curves for Fricke-infused agarose gels as obtained by nuclear magnetic resonance.

Authors:  R J Schulz; A F deGuzman; D B Nguyen; J C Gore
Journal:  Phys Med Biol       Date:  1990-12       Impact factor: 3.609

4.  Radiation therapy dosimetry using magnetic resonance imaging of polymer gels.

Authors:  M J Maryanski; G S Ibbott; P Eastman; R J Schulz; J C Gore
Journal:  Med Phys       Date:  1996-05       Impact factor: 4.071

5.  Radiation dose distributions in three dimensions from tomographic optical density scanning of polymer gels: I. Development of an optical scanner.

Authors:  J C Gore; M Ranade; M J Maryañski; R J Schulz
Journal:  Phys Med Biol       Date:  1996-12       Impact factor: 3.609

6.  A new polymer gel for magnetic resonance imaging (MRI) radiation dosimetry.

Authors:  E Pappas; T Maris; A Angelopoulos; M Paparigopoulou; L Sakelliou; P Sandilos; S Voyiatzi; L Vlachos
Journal:  Phys Med Biol       Date:  1999-10       Impact factor: 3.609

7.  A spin-spin relaxation rate investigation of the gelatin ferrous sulphate NMR dosimeter.

Authors:  C Duzenli; R Sloboda; D Robinson
Journal:  Phys Med Biol       Date:  1994-10       Impact factor: 3.609

8.  Polymer gels for magnetic resonance imaging of radiation dose distributions at normal room atmosphere.

Authors:  P M Fong; D C Keil; M D Does; J C Gore
Journal:  Phys Med Biol       Date:  2001-12       Impact factor: 3.609

9.  Investigation of the tissue equivalence of gels used for NMR dosimetry.

Authors:  T Kron; P Metcalfe; J M Pope
Journal:  Phys Med Biol       Date:  1993-01       Impact factor: 3.609

10.  Dosimetric characterization of CyberKnife radiosurgical photon beams using polymer gels.

Authors:  E Pantelis; C Antypas; L Petrokokkinos; P Karaiskos; P Papagiannis; M Kozicki; E Georgiou; L Sakelliou; I Seimenis
Journal:  Med Phys       Date:  2008-06       Impact factor: 4.071

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