| Literature DB >> 11512616 |
P Kipouros1, E Pappas, P Baras, D Hatzipanayoti, P Karaiskos, L Sakelliou, P Sandilos, I Seimenis.
Abstract
In this work the extent of the linear dose response and the dynamic dose range of N-vinylpyrrolidone-argon based (VIPAR) polymer gels were investigated. VIPAR gels were irradiated using a 6 MV linear accelerator up to 60 Gy and a Nucletron microSelectron 192Ir HDR brachytherapy source to much higher doses to cover a dose range of two orders of magnitude. They were then MR scanned at 1.5 T to obtain T2-maps. VIPAR gel measurements obtained from the two irradiation regimes were calibrated against ion chamber measurements and dose calculations derived using the AAPM TG-43 protocol respectively. A satisfying agreement between the calibration results derived using the 6 MV x-rays and the 192Ir source was found for doses up to 60 Gy, implying that the response of the VIPAR gels is independent of photon energy and dose rate. A linear R2 dose response up to approximately 40 Gy and a dynamic dose range up to at least approximately 250 Gy were observed. VIPAR gel dose measurements derived using the monoexponentially fitted brachytherapy calibration data were found to be quite accurate.Entities:
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Year: 2001 PMID: 11512616 DOI: 10.1088/0031-9155/46/8/308
Source DB: PubMed Journal: Phys Med Biol ISSN: 0031-9155 Impact factor: 3.609