Literature DB >> 30132278

A cost minimisation analysis comparing iStent accompanying cataract surgery and selective laser trabeculoplasty versus topical glaucoma medications in a public healthcare setting in New Zealand.

Kelvin Ngan1,2, Ewan Fraser3, Sophie Buller4, Alex Buller3.   

Abstract

PURPOSE: To produce an economic comparison of the iStent ab interno trabecular microbypass implant accompanying cataract surgery and selective laser trabeculoplasty (SLT) as first-line treatment versus topical medications for open-angle glaucoma in New Zealand in 2016.
METHODS: The current annual costs of 19 available fully subsidised topical glaucoma medications by Pharmaceutical Management Agency (Pharmac) in 2016 were identified. Adjustments for pharmacist prescribing charges and previously described wastage levels were applied. The costs to perform iStent implantation and the cost to perform SLT were obtained from the local distributors, with the latter taking into account staff and consumable cost. Procedure costs divided by eye drops' cost produced a break-even level in equivalent years of eye drops use.
RESULTS: The range of annual eye drop cost was NZD$42.25 to NZD$485.11, with an average of NZD$144.81. Comparison of annual eye drop cost with iStent cost revealed 3 of 19 (15.8%) drops breaking even within 5 years, 9 of 19 (47.3%) within 10 years, and 12 of 19 (63.2%) within 15 years. The cost of bilateral SLT performed by a consultant was NZD$102.30 (breaking even in 0.71 years). The equivalent cost for a registrar was NZD$97.59 (breaking even in 0.67 years).
CONCLUSION: Economically, the iStent would appear to be a reasonably cost-effective treatment for glaucoma patients undergoing cataract surgery in a public healthcare setting in New Zealand, particularly for those using more expensive topical glaucoma medications, whilst SLT appears to be a worthwhile consideration as a first-line treatment for glaucoma in New Zealand.

Entities:  

Keywords:  Cost minimisation analysis; Glaucoma medication; New Zealand; Public healthcare; Selective laser trabeculoplasty; iStent

Mesh:

Substances:

Year:  2018        PMID: 30132278     DOI: 10.1007/s00417-018-4104-8

Source DB:  PubMed          Journal:  Graefes Arch Clin Exp Ophthalmol        ISSN: 0721-832X            Impact factor:   3.117


  44 in total

1.  Phacoemulsification versus phacoemulsification with micro-bypass stent implantation in primary open-angle glaucoma: randomized double-masked clinical trial.

Authors:  Antonio M Fea
Journal:  J Cataract Refract Surg       Date:  2010-03       Impact factor: 3.351

2.  Consolidated Health Economic Evaluation Reporting Standards (CHEERS)--explanation and elaboration: a report of the ISPOR Health Economic Evaluation Publication Guidelines Good Reporting Practices Task Force.

Authors:  Don Husereau; Michael Drummond; Stavros Petrou; Chris Carswell; David Moher; Dan Greenberg; Federico Augustovski; Andrew H Briggs; Josephine Mauskopf; Elizabeth Loder
Journal:  Value Health       Date:  2013 Mar-Apr       Impact factor: 5.725

3.  Projected cost comparison of Trabectome, iStent, and endoscopic cyclophotocoagulation versus glaucoma medication in the Ontario Health Insurance Plan.

Authors:  Yiannis Iordanous; Jerrod S Kent; Cindy M L Hutnik; Monali S Malvankar-Mehta
Journal:  J Glaucoma       Date:  2014-02       Impact factor: 2.503

4.  Compliance with topical timolol treatment.

Authors:  M A Kass; M Gordon; R E Morley; D W Meltzer; J J Goldberg
Journal:  Am J Ophthalmol       Date:  1987-02-15       Impact factor: 5.258

Review 5.  Compliance and persistency in glaucoma follow-up treatment.

Authors:  Gail F Schwartz
Journal:  Curr Opin Ophthalmol       Date:  2005-04       Impact factor: 3.761

6.  The number of people with glaucoma worldwide in 2010 and 2020.

Authors:  H A Quigley; A T Broman
Journal:  Br J Ophthalmol       Date:  2006-03       Impact factor: 4.638

7.  The Ahmed Versus Baerveldt Study: Five-Year Treatment Outcomes.

Authors:  Panos G Christakis; Jeffrey W Kalenak; James C Tsai; David Zurakowski; Jeffrey A Kammer; Paul J Harasymowycz; Juan J Mura; Louis B Cantor; Iqbal I K Ahmed
Journal:  Ophthalmology       Date:  2016-08-17       Impact factor: 12.079

8.  Repeatability of selective laser trabeculoplasty.

Authors:  Julia Polat; Lindsay Grantham; Kenneth Mitchell; Tony Realini
Journal:  Br J Ophthalmol       Date:  2016-02-01       Impact factor: 4.638

Review 9.  iStent® Trabecular Microbypass Stent: An Update.

Authors:  Arthur Fernandes Resende; Neal Sanjay Patel; Michael Waisbourd; L Jay Katz
Journal:  J Ophthalmol       Date:  2016-06-20       Impact factor: 1.909

10.  iStent as a Solo Procedure for Glaucoma Patients: A Systematic Review and Meta-Analysis.

Authors:  Monali S Malvankar-Mehta; Yufeng Nancy Chen; Yiannis Iordanous; Wan Wendy Wang; John Costella; Cindy M L Hutnik
Journal:  PLoS One       Date:  2015-05-27       Impact factor: 3.240

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  11 in total

1.  A multicenter prospective comparative study evaluating cataract surgery and endoscopic cyclophotocoagulation either with or without iStent inject implantation in Brazilian patients with glaucoma.

Authors:  Francisco E Lima; João C Geraissate; Marcos P Ávila
Journal:  Int Ophthalmol       Date:  2022-10-23       Impact factor: 2.029

2.  iStent Trabecular Micro-Bypass Stent Implantation with Cataract Surgery in a Japanese Glaucoma Population.

Authors:  Koji Nitta; Yutaro Yamada; Satomi Morokado; Kazuhisa Sugiyama
Journal:  Clin Ophthalmol       Date:  2020-10-15

3.  Impact of iStent Micro-Bypass Shunt on Medicare Part B Glaucoma Surgical Expenditure.

Authors:  Jun Hui Lee; Anthony K Ma; Joshua L Warren; Christopher C Teng
Journal:  Ophthalmol Glaucoma       Date:  2020-05-22

4.  Two-Year Comparative Outcomes of First- and Second-Generation Trabecular Micro-Bypass Stents with Cataract Surgery.

Authors:  Ricardo Augusto Paletta Guedes; Daniela Marcelo Gravina; Vanessa Maria Paletta Guedes; Alfredo Chaoubah
Journal:  Clin Ophthalmol       Date:  2021-05-05

5.  Outcomes of Combined iStent Trabecular Micro-Bypass and Cataract Surgery for the Treatment of Open-Angle Glaucoma in a Saudi Population.

Authors:  Ahmed Al Habash; Omar Khan
Journal:  Clin Ophthalmol       Date:  2020-06-11

6.  Intermediate Results of iStent or iStent inject Implantation Combined with Cataract Surgery in a Real-World Setting: A Longitudinal Retrospective Study.

Authors:  Ricardo Augusto Paletta Guedes; Daniela Marcelo Gravina; Jonathan Clive Lake; Vanessa Maria Paletta Guedes; Alfredo Chaoubah
Journal:  Ophthalmol Ther       Date:  2019-02-05

7.  Second-Generation Trabecular Micro-Bypass Stents as Standalone Treatment for Glaucoma: A 36-Month Prospective Study.

Authors:  Fritz H Hengerer; Gerd U Auffarth; Christoffer Riffel; Ina Conrad-Hengerer
Journal:  Adv Ther       Date:  2019-05-22       Impact factor: 3.845

8.  One-Year Comparative Evaluation of iStent or iStent inject Implantation Combined with Cataract Surgery in a Single Center.

Authors:  Ricardo Augusto Paletta Guedes; Daniela Marcelo Gravina; Jonathan Clive Lake; Vanessa Maria Paletta Guedes; Alfredo Chaoubah
Journal:  Adv Ther       Date:  2019-08-22       Impact factor: 3.845

9.  Real-world Case Series of iStent or iStent inject Trabecular Micro-Bypass Stents Combined with Cataract Surgery.

Authors:  David Manning
Journal:  Ophthalmol Ther       Date:  2019-08-17

10.  Toll-like receptor 3 gene regulates cataract-related mechanisms via the Jagged-1/Notch signaling pathway.

Authors:  Weiwei Xie; Qihua Yu; Layi Wang; Yongqing Shao; Qingyun Bo; Guohai Wu
Journal:  Bioengineered       Date:  2022-06       Impact factor: 6.832

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