Literature DB >> 3013087

Effect of ribavirin and tributylribavirin on argentine hemorrhagic fever (Junin virus) in guinea pigs.

R H Kenyon, P G Canonico, D E Green, C J Peters.   

Abstract

Subcutaneous injections of ribavirin into guinea pigs infected intraperitoneally or intracerebrally with Junin virus significantly increased the mean time to death but did not enhance survival of the animals. We found similar results with tributylribavirin. Virus replication was delayed, but not prevented, in ribavirin-treated infected guinea pigs. The animals usually died with high virus titers in their brains and frequently were paralyzed.

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Year:  1986        PMID： 3013087      PMCID： PMC180427          DOI： 10.1128/AAC.29.3.521

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  5 in total

1.  Measurement of antibodies to Machupo virus by the indirect fluorescent technique.

Authors:  C J Peters; P A Webb; K M Johnson
Journal:  Proc Soc Exp Biol Med       Date:  1973-02

2.  Effect of immunosuppression on experimental Argentine hemorrhagic fever in guinea pigs.

Authors:  R H Kenyon; D E Green; C J Peters
Journal:  J Virol       Date:  1985-01       Impact factor: 5.103

3.  Broad-spectrum antiviral activity of Virazole: 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide.

Authors:  R W Sidwell; J H Huffman; G P Khare; L B Allen; J T Witkowski; R K Robins
Journal:  Science       Date:  1972-08-25       Impact factor: 47.728

4.  Plasma disappearance, urine excretion, and tissue distribution of ribavirin in rats and rhesus monkeys.

Authors:  E A Ferrara; J S Oishi; R W Wannemacher; E L Stephen
Journal:  Antimicrob Agents Chemother       Date:  1981-06       Impact factor: 5.191

5.  Lassa virus infection of rhesus monkeys: pathogenesis and treatment with ribavirin.

Authors:  P B Jahrling; R A Hesse; G A Eddy; K M Johnson; R T Callis; E L Stephen
Journal:  J Infect Dis       Date:  1980-05       Impact factor: 5.226
  5 in total
  13 in total

Review 1.  Viral quasispecies evolution.

Authors:  Esteban Domingo; Julie Sheldon; Celia Perales
Journal:  Microbiol Mol Biol Rev       Date:  2012-06       Impact factor: 11.056

2.  Ribavirin can be mutagenic for arenaviruses.

Authors:  Héctor Moreno; Isabel Gallego; Noemí Sevilla; Juan Carlos de la Torre; Esteban Domingo; Verónica Martín
Journal:  J Virol       Date:  2011-05-11       Impact factor: 5.103

Review 3.  Drug discovery technologies and strategies for Machupo virus and other New World arenaviruses.

Authors:  Sheli R Radoshitzky; Jens H Kuhn; Fabian de Kok-Mercado; Peter B Jahrling; Sina Bavari
Journal:  Expert Opin Drug Discov       Date:  2012-05-19       Impact factor: 6.098

4.  Ribavirin prophylaxis and therapy for experimental argentine hemorrhagic fever.

Authors:  K T McKee; J W Huggins; C J Trahan; B G Mahlandt
Journal:  Antimicrob Agents Chemother       Date:  1988-09       Impact factor: 5.191

5.  Aerosol and intraperitoneal administration of ribavirin and ribavirin triacetate: pharmacokinetics and protection of mice against intracerebral infection with influenza A/WSN virus.

Authors:  B E Gilbert; P R Wyde; S Z Wilson; R K Robins
Journal:  Antimicrob Agents Chemother       Date:  1991-07       Impact factor: 5.191

6.  Glycoprotein-Specific Antibodies Produced by DNA Vaccination Protect Guinea Pigs from Lethal Argentine and Venezuelan Hemorrhagic Fever.

Authors:  Joseph W Golden; Piet Maes; Steven A Kwilas; John Ballantyne; Jay W Hooper
Journal:  J Virol       Date:  2016-01-20       Impact factor: 5.103

7.  Evaluation of Lassa antiviral compound ST-193 in a guinea pig model.

Authors:  Kathleen A Cashman; Mark A Smith; Nancy A Twenhafel; Ryan A Larson; Kevin F Jones; Robert D Allen; Dongcheng Dai; Jarasvech Chinsangaram; Tove' C Bolken; Dennis E Hruby; Sean M Amberg; Lisa E Hensley; Mary C Guttieri
Journal:  Antiviral Res       Date:  2011-03-01       Impact factor: 5.970

8.  Favipiravir (T-705) inhibits Junín virus infection and reduces mortality in a guinea pig model of Argentine hemorrhagic fever.

Authors:  Brian B Gowen; Terry L Juelich; Eric J Sefing; Trevor Brasel; Jennifer K Smith; Lihong Zhang; Bersabeh Tigabu; Terence E Hill; Tatyana Yun; Colette Pietzsch; Yousuke Furuta; Alexander N Freiberg
Journal:  PLoS Negl Trop Dis       Date:  2013-12-26

9.  An attenuated Machupo virus with a disrupted L-segment intergenic region protects guinea pigs against lethal Guanarito virus infection.

Authors:  Joseph W Golden; Brett Beitzel; Jason T Ladner; Eric M Mucker; Steven A Kwilas; Gustavo Palacios; Jay W Hooper
Journal:  Sci Rep       Date:  2017-07-05       Impact factor: 4.379

Review 10.  Junín virus pathogenesis and virus replication.

Authors:  Ashley Grant; Alexey Seregin; Cheng Huang; Olga Kolokoltsova; Allan Brasier; Clarence Peters; Slobodan Paessler
Journal:  Viruses       Date:  2012-10-19       Impact factor: 5.048
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